Výsledky vyhledávání - "Brian O'Mathúna"

Akademický článek

Clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'): the influence of gender and genetics (CYP2D6, COMT, 5-HTT).

Autor: Ricardo Pardo-Lozano, Magí Farré, Samanta Yubero-Lahoz, Brian O'Mathúna, Marta Torrens, Cristina Mustata, Clara Pérez-Mañá, Klaus Langohr, Elisabet Cuyàs, Marcel lí Carbó, Rafael de la Torre

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47599 (2012)

The synthetic psychostimulant MDMA (± 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). It has been suggested that

Externí odkaz: https://doaj.org/article/bace9d6b7b7444f5a3c29cf7e11c0bea

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The Consequences of 3,4-Methylenedioxymethamphetamine Induced CYP2D6 Inhibition in Humans

Autor: Ricardo Pardo, Amin Rostami-Hodjegan, Silvana Maluf, Jiansong Yang, Rafael de la Torre, Sergio Abanades, Marta Torrens, Geoffrey T. Tucker, Elisabet Cuyàs, Magí Farré, Brian O'Mathúna

Publikováno v: Journal of Clinical Psychopharmacology. 28:523-529

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a widely abused substituted amphetamine. MDMA is predominantly O-demethylenated in humans by cytochrome P450 isoforms 2D6 and 1A2 (CYP2D6 and CYP CYP1A2, respectively). MDMA is also a mechanism-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb2704789e709e06056711327f3f57f
https://doi.org/10.1097/jcp.0b013e318184ff6e

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Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): the influence of gender and genetics (CYP2D6, COMT, 5-HTT)

Autor: Brian O'Mathúna, Ricardo Pardo-Lozano, Rafael de la Torre, Elisabet Cuyàs, Clara Pérez-Mañá, Klaus Langohr, Samanta Yubero-Lahoz, Marta Torrens, Cristina Mustata, Marcel·li Carbó, Magí Farré

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e47599 (2012)

The synthetic psychostimulant MDMA (±3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). It has been suggested that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698a32e6c78956ab9f1964d1da952c13
https://hdl.handle.net/2117/17091

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