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pro vyhledávání: '"Brian O'Conner"'
Autor:
Qianqian Zhang, Gongyi Zhang, Philippa Marrack, Zhongzhou Chen, Tengyao Song, Srinivas Ramachandran, Thomas Danhorn, Haolin Liu, John W. Kappler, Carrie Happoldt, Xinjian Liu, Tzu L. Phang, Ting-Hui Tu, Nova Fong, Ralf Janknecht, Sangphil Oh, Pirooz V. Parsa, Laura Harmacek, Qian Zhang, Brian O’Conner, Schuyler Lee, Chuan-Yuan Li, Sonia M. Leach
Publikováno v:
Proc Natl Acad Sci U S A
More than 30% of genes in higher eukaryotes are regulated by RNA polymerase II (Pol II) promoter proximal pausing. Pausing is released by the positive transcription elongation factor complex (P-TEFb). However, the exact mechanism by which this occurs