Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Brian N. Ling"'
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:83-88
1. Angiotensin II (AngII)-induced, activation of phospholipase C (PLC) and Ca2+-dependent Cl- channels is an important signal transduction pathway for the regulation of vascular smooth muscle cell (VSMC) and glomerular mesangial cell contraction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4421d98a8fdf8468671511bd3a2b41dc
https://doi.org/10.1111/j.1440-1681.1996.tb03067.x
https://doi.org/10.1111/j.1440-1681.1996.tb03067.x
Autor:
Brian N. Ling
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:89-94
1. In response to vasoactive peptides (e.g. angiotensin II (AngII), vasopressin, endothelin-1, platelet-activating factor), glomerular mesangial cell contraction is mediated through activation of a Ca2+-dependent Cl- conductance that, in turn, promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4e51c821021357e8d9992ba0c263f2
https://doi.org/10.1111/j.1440-1681.1996.tb03068.x
https://doi.org/10.1111/j.1440-1681.1996.tb03068.x
Publikováno v:
Kidney International. 53:1259-1268
Erythropoietin receptor-operated Ca 2+ channels: Activation by phospholipase C-γ1. Erythropoietin (EPO) increases Ca 2+ influx in vascular smooth muscle cells and acts both as a direct vasoconstrictor and vascular growth factor (that is, angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e86a001d20b25aaa71318413d504695
https://doi.org/10.1046/j.1523-1755.1998.00887.x
https://doi.org/10.1046/j.1523-1755.1998.00887.x
Publikováno v:
American Journal of Physiology-Cell Physiology. 272:C2019-C2030
The binding of vasoactive peptides to their respective G protein-coupled receptors has been implicated in the pathogenesis of vascular smooth muscle cell proliferation, leading to the development of hypertension, arteriosclerosis, and restenosis afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ff05394b98b52b38b1701bf2f2c7f8
https://doi.org/10.1152/ajpcell.1997.272.6.c2019
https://doi.org/10.1152/ajpcell.1997.272.6.c2019
Autor:
M. S. Gallego, Brian N. Ling
Publikováno v:
American Journal of Physiology-Renal Physiology. 271:F451-F460
We used patch-clamp methods to investigate the effects of basolateral endothelin-1 (ET-1) on the amiloride-sensitive Na+ channel in A6 distal nephron cells. One hundred picomolar ET-1 decreased channel activity via an increase in mean time closed (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb04c0df458f3f836dd81ad4b7779fe
https://doi.org/10.1152/ajprenal.1996.271.2.f451
https://doi.org/10.1152/ajprenal.1996.271.2.f451
Publikováno v:
Europe PubMed Central
Angiotensin II (ANG II)-induced, activation of phospholipase C (PLC) and Ca(2+)-dependent Cl-channels is an important signal transduction pathway for mesangial cell contraction and growth. Although ANG II receptors are traditionally though to be G pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5605d2a6bd9d4a2e832fb1f642144ad3
https://doi.org/10.1152/ajpcell.1996.270.6.c1834
https://doi.org/10.1152/ajpcell.1996.270.6.c1834
Autor:
He-Ping Ma, Brian N. Ling
Publikováno v:
American Journal of Physiology-Renal Physiology. 270:F798-F805
To investigate the effects of luminal adenosine on amiloride-sensitive Na+ channels, we applied the cell-attached patch-clamp technique to A6 distal nephron cells. Exposure to luminal 30 nM adenosine increased number of channels x open probability (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014e9461f6b8b68bd2189c81ba3b53f4
https://doi.org/10.1152/ajprenal.1996.270.5.f798
https://doi.org/10.1152/ajprenal.1996.270.5.f798
Publikováno v:
Cellular Signalling. 8:21-26
Angiotensin II is a potent vasoconstrictor that is important in the control of systemic blood pressure. All the hemodynamic effects of angiotensin II result from the AT1 receptor which has the structural features of a seven transmembrane receptor. Bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a154a370b6a3e06f845ede2a2aad471
https://doi.org/10.1016/0898-6568(95)02016-0
https://doi.org/10.1016/0898-6568(95)02016-0
Autor:
Asit Patnaik, Thomas R. Kleyman, Mitchell L. Halperin, Ching-Bun Chen, Mahboob Lessan-Pezeshki, Lynn E. Schlanger, Brian N. Ling, Martin Schreiber
Publikováno v:
Kidney International. 49(1):82-87
Antikaliuretic action of trimethoprim is minimized by raising urine pH. This study was designed to test the hypothesis that the antikaliuresis caused by trimethoprim could be diminished by alkalinizing the luminal fluid in the CCD, thereby converting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7617cb577197d51febeb093577bb91
Publikováno v:
Kidney International. 48:1158-1166
Glomerular mesangial cells are located between and within glomerular capillary loops, phenotypically resemble vascular smooth muscle cells, and play an essential role in regulating glomerular filtration and growth [1–6]. In response to locally-prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723386a81470046acbac5887516ab51e
https://doi.org/10.1038/ki.1995.399
https://doi.org/10.1038/ki.1995.399