Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Brian M. Zeglis"'
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT VlsE (variable major protein-like sequence, expressed) is an outer surface protein of the Lyme disease pathogen (Borreliella species) responsible for its within-host antigenic variation and a key diagnostic biomarker of Lyme disease. However
Externí odkaz:
https://doaj.org/article/07a522b29b3e48bc95c8324d5aaf7428
Autor:
Outi Keinänen, Eric J. Dayts, Cindy Rodriguez, Samantha M. Sarrett, James M. Brennan, Mirkka Sarparanta, Brian M. Zeglis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The proliferation of plastics in the environment continues at an alarming rate. Plastic particles have been found to be persistent and ubiquitous pollutants in a variety of environments, including sea water, fresh water, soil, and air. In li
Externí odkaz:
https://doaj.org/article/1dc3c5928bad4f8db06b2d7fd448c29b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Poly(ADP-ribose)polymerase-1 (PARP1) is a DNA repair enzyme highly expressed in the nuclei of mammalian cells, with a structure and function that have attracted interest since its discovery. PARP inhibitors, moreover, can be used to induce synthetic
Externí odkaz:
https://doaj.org/article/cc5af923006348f2a7dc040330feceab
Autor:
Outi Keinänen, Kimberly Fung, Jacob Pourat, Vilma Jallinoja, Delphine Vivier, NagaVara Kishore Pillarsetty, Anu J. Airaksinen, Jason S. Lewis, Brian M. Zeglis, Mirkka Sarparanta
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Background Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pret
Externí odkaz:
https://doaj.org/article/0fcf170bc14143cab53aa92849dad3cf
Autor:
Kimberly Fung, Delphine Vivier, Outi Keinänen, Elaheh Khozeimeh Sarbisheh, Eric W. Price, Brian M. Zeglis
Publikováno v:
Molecules, Vol 25, Iss 10, p 2315 (2020)
High expression levels of the tumor-associated antigen MUC1 have been correlated with tumor aggressiveness, poor response to therapy, and poor survival in several tumor types, including breast, pancreatic, and epithelial ovarian cancer. Herein, we re
Externí odkaz:
https://doaj.org/article/7954de6aef7d49319329ba50d13b4848
Autor:
Douglas S. MacPherson, Dobeen Hwang, Samantha M. Sarrett, Outi Keinänen, Cindy Rodriguez, Christoph Rader, Brian M. Zeglis
Publikováno v:
Mol Pharm
Site-specifically modified radioimmunoconjugates exhibit superior in vitro and in vivo behavior compared to analogues synthesized via traditional stochastic methods. However, the development of approaches to site-specific bioconjugation that combine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44eaaf5f34f272baab167425e39bbe17
https://doi.org/10.1021/acs.molpharmaceut.2c00700
https://doi.org/10.1021/acs.molpharmaceut.2c00700
Autor:
Brian M, Zeglis, Jason S, Lewis
Publikováno v:
New England Journal of Medicine. 387:2291-2293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb2bae5c21d76db7f7560d22890bf7
https://doi.org/10.1056/nejmcibr2213596
https://doi.org/10.1056/nejmcibr2213596
Autor:
Outi Keinänen, Samantha M. Sarrett, Samantha Delaney, Cindy Rodriguez, Eric J. Dayts, Emily Capone, Frederic Sauniere, Rodolfo Ippoliti, Gianluca Sala, Stefano Iacobelli, Brian M. Zeglis
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e75158fa1c62fb90c8b3f7fd377a05
https://doi.org/10.1021/acs.molpharmaceut.3c00241
https://doi.org/10.1021/acs.molpharmaceut.3c00241
Publikováno v:
Nature Protocols.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b6646d05fe3723ad0e344b51ca4036
https://doi.org/10.1038/s41596-023-00825-8
https://doi.org/10.1038/s41596-023-00825-8
Publikováno v:
Molecular Imaging and Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a7f764bdf78a45577f0f5e5d2fd4af
https://doi.org/10.1007/s11307-023-01818-5
https://doi.org/10.1007/s11307-023-01818-5