Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Brian M. Westwood"'
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2026 (2022)
Muscadine grapes are abundant in dietary polyphenols, but their effect on hypertension-induced cardiac damage is limited. This study assessed whether a muscadine grape skin/seed extract supplement (MGES) prevents hypertension-induced cardiac damage a
Externí odkaz:
https://doaj.org/article/914aec2a001e40fead18db1a179d0d7a
Autor:
David C. Merrill, Liliya M. Yamaleyeva, Kai Chen, Cheryl Moorefield, JaNae Joyner, Courtney Givner, Brian M. Westwood, Liomar A. A. Neves, K. Bridget Brosnihan, Kristy Lanier
Publikováno v:
Endocrine. 69:410-419
To address whether differential regulation of the renin-angiotensin-aldosterone system occurs in pre-eclampsia, we performed an analysis of the time course of circulating and urinary profiles of the vasoconstrictor (Ang II) and the vasodilator [Ang-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b161190b9ae031d24021a6dab0b46c
https://doi.org/10.1007/s12020-020-02296-3
https://doi.org/10.1007/s12020-020-02296-3
Autor:
Brian M. Westwood, Maria T Xie, Victoria E Surratt, Adam S. Wilson, Ravi Singh, Lihong Shi, Bethany A. Kerr, Katherine L. Cook, Kendall L. Langsten, JoLyn Turner
Most women diagnosed with breast cancer (BC) have estrogen receptor alpha positive (ER+) disease. ER+ BC preferentially metastasizes to bone; at which time it is considered incurable. Treatments for bone metastasis have not advanced in decades, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a74cbe5ea234adc562a19d26eecf923
https://doi.org/10.1101/2021.09.16.460665
https://doi.org/10.1101/2021.09.16.460665
Autor:
Marianne Collard, Brian M. Westwood, E. Ann Tallant, Heather Brown-Harding, Nataleigh Austin, Patricia E. Gallagher
Background Triple negative breast cancer (TNBC) has a high propensity to metastasize and no treatments are available to slow or prevent metastatic progression. The goal of this study is to determine whether a proprietary high-polyphenol content musca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae92d97108275e90847935bfb856cd3
https://doi.org/10.21203/rs.3.rs-384168/v1
https://doi.org/10.21203/rs.3.rs-384168/v1
Angiotensinogen uptake and stimulation of oxidative stress in human pigment retinal epithelial cells
Publikováno v:
Peptides. 152:170770
We previously reported that isolated proximal tubules (PT) internalize the precursor protein angiotensinogen and that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0856bed2d0b2d5aa225dc11240fb97
https://doi.org/10.1016/j.peptides.2022.170770
https://doi.org/10.1016/j.peptides.2022.170770
Skeletal muscle extracellular matrix remodeling with worsening glycemic control in nonhuman primates
Autor:
Brian M. Westwood, Kylie Kavanagh, Chrissy Sherrill, Jeff W. Chou, Laura A. Cox, Tony E. Reeves, Alistaire Ruggiero, Gregory A. Hawkins, Ashley T. Davis, Nicholette D. Palmer
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Type 2 diabetes (T2D) development may be mediated by skeletal muscle (SkM) function, which is responsible for >80% of circulating glucose uptake. The goals of this study were to assess changes in global- and location-level gene expression, remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0d88bd2ca15808cb86eaa0a2088cf9
https://pubmed.ncbi.nlm.nih.gov/33206559
https://pubmed.ncbi.nlm.nih.gov/33206559
Autor:
Debra I. Diz, A’ja V. Duncan, Nildris Cruz Diaz, Liliya M. Yamaleyeva, E. Ann Tallant, Wayne Graham, Patricia E. Gallagher, Brian M. Westwood, Mark C. Chappell
Publikováno v:
Hypertension. 76
Physical performance and systolic blood pressure (SBP) during aging in normotensive female Sprague-Dawley (SD) and hypertensive (mRen2)27 transgenic rats were assessed following long-term treatment with a Muscadine Grape Extract (MGE, Piedmont Resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e9adc0599cd54687859787d6399417
https://doi.org/10.1161/hyp.76.suppl_1.p053
https://doi.org/10.1161/hyp.76.suppl_1.p053
Autor:
E. Ann Tallant, Patricia E. Gallagher, Jay Kirby, Brian M. Westwood, Omeed Rahimi, Jasmina Varagic
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 318(4)
Doxorubicin (Dox) is an effective chemotherapeutic for a variety of pediatric malignancies. Unfortunately, Dox administration often results in a cumulative dose-dependent cardiotoxicity that manifests with marked oxidative stress, leading to heart fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e47cac4e257a670bd9c5997aadc32b2
https://pubmed.ncbi.nlm.nih.gov/32083974
https://pubmed.ncbi.nlm.nih.gov/32083974
Autor:
Yismeilin R. Feliz-Mosquea, Brian M. Westwood, Jasmina Varagic, Rajarshi Guha, Craig J. Thomas, David D. Roberts, Lesley A. Mathews Griner, Qing-Rong Chen, Adam S. Wilson, Giselle C. Meléndez, David R. Soto-Pantoja, Marc Ferrer, Anthony L. Schwartz, Ashley A. Christensen, Katherine L. Cook, Maria J. Merino
Publikováno v:
Breast Cancer Research and Treatment. 172:69-82
BACKGROUND: A perennial challenge in systemic cytotoxic cancer therapy is to eradicate primary tumors and metastatic disease while sparing normal tissue from off-target effects of chemotherapy. Anthracyclines such as doxorubicin are effective chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580ac19929f095661dffd5c9c1ec3f0c
https://doi.org/10.1007/s10549-018-4884-x
https://doi.org/10.1007/s10549-018-4884-x
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15759 (2011)
Angiotensin-(1-12) [Ang-(1-12)] functions as an endogenous substrate for the productions of Ang II and Ang-(1-7) by a non-renin dependent mechanism. This study evaluated whether Ang-(1-12) is incorporated by neonatal cardiac myocytes and the enzymati
Externí odkaz:
https://doaj.org/article/0bbbb380de8f4fc0b447d5b0c421c22b