Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brian M. Wendel"'
Autor:
Brian M. Wendel, Hualiang Pi, Larissa Krüger, Christina Herzberg, Jörg Stülke, John D. Helmann
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Osmotic stress is a significant physical challenge for free-living cells. Cells from all three domains of life maintain viability during osmotic stress by tightly regulating the major cellular osmolyte potassium (K+) and by import or synthes
Externí odkaz:
https://doaj.org/article/6d5720a93a0e4d72aa70917dced4bdf0
Publikováno v:
Microbiology. 169
In Bacillus subtilis, iron homeostasis is maintained by the ferric uptake regulator (Fur) and manganese homeostasis relies on the manganese transport regulator (MntR). Both Fur and MntR function as bi-functional metalloregulators that repress import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3f6d2912ef7460c4cd4fe2233dc379f
https://doi.org/10.1099/mic.0.001289
https://doi.org/10.1099/mic.0.001289
Publikováno v:
DNA
Volume 1
Issue 1
Pages 3-25
Volume 1
Issue 1
Pages 3-25
In Escherichia coli, several enzymes have been identified that participate in completing replication on the chromosome, including RecG, SbcCD, ExoI, and RecBCD. However, other enzymes are likely to be involved and the precise enzymatic mechanism by w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5206b4cd631d247da7fd5eab02488914
https://doi.org/10.3390/dna1010003
https://doi.org/10.3390/dna1010003
Publikováno v:
Genes to Cells. 26:94-108
Replication initiation, elongation and completion are tightly coordinated to ensure that all sequences replicate precisely once each generation. UV-induced DNA damage disrupts replication and delays elongation, which may compromise this coordination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da4cbc4b7d90c89c91f7dff2f57685b
https://doi.org/10.1111/gtc.12826
https://doi.org/10.1111/gtc.12826
Publikováno v:
Nucleic Acids Research
Microorganisms use zinc-sensing regulators to alter gene expression in response to changes in the availability of zinc, an essential micronutrient. Under zinc-replete conditions, the Fur-family metalloregulator Zur binds to DNA tightly in its metalla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d0dcf4affb8cda187f7eb11d2c92a7
https://doi.org/10.1093/nar/gkaa056
https://doi.org/10.1093/nar/gkaa056
Autor:
Nicklas A. Hamilton, Avery E. Jehru, William N. Samples, Brian M. Wendel, Parisa D. Mokhtari, Charmain T. Courcelle, Justin Courcelle
Publikováno v:
Journal of Biological Chemistry. 299:103013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::982400f58076abfe61403177b27a176d
https://doi.org/10.1016/j.jbc.2023.103013
https://doi.org/10.1016/j.jbc.2023.103013
Autor:
John D. Helmann, Brian M. Wendel, Nishanth Makthal, Hackwon Do, Randall J. Olsen, James M. Musser, Muthiah Kumaraswami
Publikováno v:
Infect Immun
Colonization by pathogenic bacteria depends on their ability to overcome host nutritional defenses and acquire nutrients. The human pathogen group A streptococcus (GAS) encounters the host defense factor calprotectin (CP) during infection. CP inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da675ff8df624aac452b4e0e0adcef7
https://doi.org/10.1128/iai.00097-20
https://doi.org/10.1128/iai.00097-20
Publikováno v:
J Bacteriol
Transition metals are essential for life but are toxic when in excess. Metal ion intoxication may result from the mismetallation of essential metal-dependent enzymes with a noncognate metal. To begin to identify enzymes and processes that are suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a2779f14c856b9d3612ce722f206fd
https://doi.org/10.1128/jb.00711-19
https://doi.org/10.1128/jb.00711-19
Publikováno v:
Mol Microbiol
The accurate completion of DNA replication on the chromosome requires RecBCD and structure specific SbcCD ExoI nucleases. However, the substrates and mechanism by which this reaction occurs remains unknown. Here we show that these completion enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad9183afaedf81e984f397c8bfc18e1
https://pubmed.ncbi.nlm.nih.gov/30883946
https://pubmed.ncbi.nlm.nih.gov/30883946
SbcC-SbcD are the bacterial orthologs of Mre11-Rad50, a nuclease complex essential for genome stability, normal development, and viability in mammals. In vitro, these enzymes degrade long DNA palindromic structures. When inactivated along with ExoI i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5bcc660cba83a2bb273d360fe80273
https://europepmc.org/articles/PMC5777064/
https://europepmc.org/articles/PMC5777064/
