Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Brian M. Freed"'
Autor:
Cecilia C. Low Wang, Tae Chong, Garrett Moore, Benjamin Echalier, Nicola Haakonsen, James E. Carter, David Mathes, Judith Hsia, Toan Thang Phan, Ivor J. Lim, Brian M. Freed
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1375 (2024)
Background: Mesenchymal stromal/stem cells (MSCs) play a critical role in wound healing. Corlicyte® is an MSC product derived from allogeneic umbilical cord tissue donated under an institutional review board-approved protocol and processed in accord
Externí odkaz:
https://doaj.org/article/7112a3c06d824163a7c6522fb28549f1
Autor:
Xiyuan Bai, Deepshikha Verma, Cindy Garcia, Ariel Musheyev, Kevin Kim, Lorelenn Fornis, David E. Griffith, Li Li, Nicholas Whittel, Jacob Gadwa, Tamara Ohanjanyan, Matthew J. Eggleston, Manuel Galvan, Brian M. Freed, Diane Ordway, Edward D. Chan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionA strong epidemiologic link exists between cigarette smoke (CS) exposure and susceptibility to tuberculosis (TB). Macrophage and murine studies showed that CS and nicotine impair host-protective immune cells against Mycobacterium tubercul
Externí odkaz:
https://doaj.org/article/26d83c75c82943268a6d72ddd2c09bd9
Autor:
Xiyuan Bai, Ashley M. Buckle, Eszter K. Vladar, Edward N. Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B. Fornis, Abraham Majluf-Cruz, Randolph V. Fugit, Brian M. Freed, Soohyun Kim, Robert A. Sandhaus, Edward D. Chan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The cell surface serine protease Transmembrane Protease 2 (TMPRSS2) is required to cleave the spike protein of SARS-CoV-2 for viral entry into cells. We determined whether negatively-charged heparin enhanced TMPRSS2 inhibition by alpha-1-ant
Externí odkaz:
https://doaj.org/article/87deec5add75457e8d052d536d4a5f93
Autor:
Julie Lang, Alexis D. Leal, Juan A. Marín-Jiménez, Sarah J. Hartman, Jeremy Shulman, Natalie M. Navarro, Matthew S. Lewis, Anna Capasso, Stacey M. Bagby, Bethlehem W. Yacob, Morgan MacBeth, Brian M. Freed, S. Gail Eckhardt, Kimberly Jordan, Patrick J. Blatchford, Roberta Pelanda, Christopher H. Lieu, Wells A. Messersmith, Todd M. Pitts
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immune checkpoint inhibitors have been found to be effective in metastatic MSI-high colorectal cancers (CRC), however, have no efficacy in microsatellite stable (MSS) cancers, which comprise the majority of mCRC cases. Cabozantinib is a small molecul
Externí odkaz:
https://doaj.org/article/4e169c4be6074370bda2cb5901dfda6f
Autor:
Xiyuan Bai, Ashley M. Buckle, Eszter K. Vladar, Edward N. Janoff, Reeti Khare, Diane Ordway, David Beckham, Lorelenn B. Fornis, Abraham Majluf-Cruz, Randolph V. Fugit, Brian M. Freed, Soohyun Kim, Robert A. Sandhaus, Edward D. Chan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/00ca77f49f1541f1b75658582a402a13
Autor:
Juan A. Marín-Jiménez, Anna Capasso, Matthew S. Lewis, Stacey M. Bagby, Sarah J. Hartman, Jeremy Shulman, Natalie M. Navarro, Hui Yu, Chris J. Rivard, Xiaoguang Wang, Jessica C. Barkow, Degui Geng, Adwitiya Kar, Ashley Yingst, Dejene M. Tufa, James T. Dolan, Patrick J. Blatchford, Brian M. Freed, Raul M. Torres, Eduardo Davila, Jill E. Slansky, Roberta Pelanda, S. Gail Eckhardt, Wells A. Messersmith, Jennifer R. Diamond, Christopher H. Lieu, Michael R. Verneris, Jing H. Wang, Katja Kiseljak-Vassiliades, Todd M. Pitts, Julie Lang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Over the past decade, immunotherapies have revolutionized the treatment of cancer. Although the success of immunotherapy is remarkable, it is still limited to a subset of patients. More than 1500 clinical trials are currently ongoing with a goal of i
Externí odkaz:
https://doaj.org/article/6424fe4cd62341bb904d284bc361adfc
Autor:
Christina L, Roark, Bethany E, Ho, Michael T, Aubrey, Cheri, Anobile, Sapir, Israeli, Tzu L, Phang, Danielle, Braxton, Andrea P, Ho, Brian M, Freed
Publikováno v:
Human Immunology. 83:730-735
The "heterozygote advantage" hypothesis has been postulated regarding the role of human leukocyte antigen (HLA) in non-Hodgkin lymphoma (NHL), where homozygous loci are associated with an increased risk of disease. In this retrospective study, we ana
Autor:
Melhem Solh, Michael T Aubrey, Xu Zhang, Asad Bashey, Brian M Freed, Christina L Roark, Lizamarie Bachier-Rodriguez, Lawrence E. Morris, H. Kent Holland, Scott R. Solomon
Publikováno v:
Blood. 140:7738-7739
Autor:
Scott R. Solomon, Michael T. Aubrey, Xu Zhang, Katelin C. Jackson, Christina L. Roark, Brian M. Freed, Lawrence E. Morris, H. Kent Holland, Melhem M. Solh, Asad Bashey
Publikováno v:
Transplantation and Cellular Therapy. 28:601.e1-601.e8
The role of NK cell alloreactivity on outcomes after T cell-replete haploidentical donor transplantation (HIDT) remains uncertain. After transplantation, newly formed NK cells are licensed through interactions of donor inhibitory KIR (iKIR) and NKG2A
Autor:
Scott R. Solomon, Michael T Aubrey, Xu Zhang, Katelin Jackson, Christina L Roark, Brian M Freed, Melhem Solh, Lawrence E Morris, H. Kent Holland, Asad Bashey
Publikováno v:
Transplantation and Cellular Therapy. 28:S23-S24