Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brian M. Cartwright"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine-protein kinase of the PI3K family and is well known for its key role in regulating DNA damage responses in the nucleus. In addition to its nuclear functions, ATR also was foun
Externí odkaz:
https://doaj.org/article/b225aefc7c594ab7b563f079292e2f77
Autor:
Xiaochun Yu, Yue Zou, Yetunde Makinwa, Hui Wang-Heaton, Phillip R. Musich, Brian M. Cartwright, Nikolozi Shkriabai, Mamuka Kvaratskhelia, Zhengke Li, Benjamin Hilton, Qian Chen, Shengheng Guan
Publikováno v:
The FASEB Journal
Hyperactivation of PARP1 is known to be a major cause of necrotic cell death by depleting NAD+/ATP pools during Ca2+ overload which is associated with many ischemic diseases. However, little is known about how PARP1 hyperactivity is regulated during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d2d313e542109c5f6c17fd92cec8ab
http://europepmc.org/articles/PMC8252533
http://europepmc.org/articles/PMC8252533
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine-protein kinase of the PI3K family and is well known for its key role in regulating DNA damage responses in the nucleus. In addition to its nuclear functions, ATR also was foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ed2fb11ccc807899442138dcedd123
https://www.frontiersin.org/article/10.3389/fcell.2020.00813/full
https://www.frontiersin.org/article/10.3389/fcell.2020.00813/full
Autor:
Michael H. Stone, Mark A. South, Mary E. A. Howell, M. Lee, Michael W. Ramsey, Brian M. Cartwright, Charles A. Stuart
Publikováno v:
Journal of Strength and Conditioning Research. 31:798-808
Stuart, CA, Lee, ML, South, MA, Howell, MEA, Cartwright, BM, Ramsey, MW, and Stone, MH. Pre-training muscle characteristics of subjects who are obese determine how well exercise training will improve their insulin responsiveness. J Strength Cond Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64c19b5f9f70668ccd352b69c584bed
https://doi.org/10.1519/jsc.0000000000001530
https://doi.org/10.1519/jsc.0000000000001530
Autor:
Tahmina Hossain Ahmed, Thomas C. Jones, Mahbubur Rahman, Rebecca J. Wilson, Brian M. Cartwright
Publikováno v:
General and Comparative Endocrinology. 299:113580
Monoamine oxidase (MAO) is a mitochondrial membrane-bound enzyme that catalyzes the oxidative deamination of monoamines in a wide array of organisms. While the enzyme monoamine oxidase has been studied extensively in its role in moderating behavior i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08527fa58ef0f1862919211913883863
https://doi.org/10.1016/j.ygcen.2020.113580
https://doi.org/10.1016/j.ygcen.2020.113580
Publikováno v:
Current Human Cell Research and Applications ISBN: 9789811072956
The maintenance of genomic stability in the face of endogenous and exogenous sources of DNA damage requires a robust and comprehensive cellular response. This response, appropriately deemed the DNA damage response (DDR), facilitates changes in the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d89b52859a110c6a66941abaf1aff37
https://doi.org/10.1007/978-981-10-7296-3_6
https://doi.org/10.1007/978-981-10-7296-3_6
Autor:
Brian M. Cartwright, Hui Tang, Ji Liu, Antonio E. Rusiñol, Benjamin Hilton, Phillip R. Musich, Youjie Wang, Rowdy Jones, Yiyong Liu, Yue Zou, Maya Breitman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(9)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that is caused by a point mutation in the LMNA gene, resulting in production of a truncated farnesylated-prelamin A protein (progerin). We previously reported that XPA mislocalize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f50ef43ac8be29172620989d19cf0e
https://pubmed.ncbi.nlm.nih.gov/28515154
https://pubmed.ncbi.nlm.nih.gov/28515154
Autor:
Xiao Zhen Zhou, Brian M. Cartwright, Kun Ping Lu, Hui Wang, Moises A. Serrano, Phillip R. Musich, Benjamin Hilton, Yue Zou, Zhengke Li
Publikováno v:
Molecular Cell. 61(3)
ATR, a PI3K-like protein kinase, plays a key role in regulating DNA damage responses. Its nuclear checkpoint kinase function is well documented, but little is known about its function outside the nucleus. Here we report that ATR has an antiapoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f65d29adbef4256ace0fb8dc67f3b1
Autor:
Steve M. Patrick, Mohan Dangeti, Phillip R. Musich, Moises A. Serrano, Brian M. Cartwright, Yue Zou, Marina Roginskaya, Zhengke Li
Publikováno v:
Oncogene
Homologous recombination (HR) and nonhomologous end joining (NHEJ) are two distinct DNA double-stranded break (DSB) repair pathways. Here, we report that DNA-dependent protein kinase (DNA-PK), the core component of NHEJ, partnering with DNA-damage ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a3d9752f658b5fc9bdf712101c0e6a
https://doi.org/10.1038/onc.2012.257
https://doi.org/10.1038/onc.2012.257
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68297 (2013)
PLoS ONE
PLoS ONE
Xeroderma pigmentosum Group A (XPA) is a crucial factor in mammalian nucleotide excision repair (NER) and nuclear import of XPA from the cytoplasm for NER is regulated in cellular DNA damage responses in S-phase. In this study, experiments were carri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5efdc9454b405f54082d393b620956c
http://europepmc.org/articles/PMC3704644?pdf=render
http://europepmc.org/articles/PMC3704644?pdf=render