Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Brian M. Adger"'
Publikováno v:
Tetrahedron Letters. 37:6399-6402
Enantiomerically pure (S)-Bupivacaine is synthesised from the chiral pool using cheap and readily available (S)-lysine. The key steps in this efficient synthesis include an oxidative de-amination and stereospecific ring closure to form the pipecolami
Autor:
Gideon Grogan, Ray McCague, Brian M. Adger, M. T. Bes, Sandrine Pedragosa-Moreau, Stanley M. Roberts, Peter W. H. Wan, Andrew Willetts, Raffaella Villa
Publikováno v:
ChemInform. 26
Publikováno v:
ChemInform. 27
Enantiomerically pure (S)-Bupivacaine is synthesised from the chiral pool using cheap and readily available (S)-lysine. The key steps in this efficient synthesis include an oxidative de-amination and stereospecific ring closure to form the pipecolami
Publikováno v:
ChemInform. 28
An efficient synthesis of racemic tert-leucine from trimethylpyruvic acid using a Leuckart type reaction is described. A facile resolution of an intermediate with α-methylbenzylamine allows entry into either (R)-or (S)-tert-leucine.
Publikováno v:
Tetrahedron Letters. 38:2153-2154
An efficient synthesis of racemic tert-leucine from trimethylpyruvic acid using a Leuckart type reaction is described. A facile resolution of an intermediate with α-methylbenzylamine allows entry into either (R)-or (S)-tert-leucine.
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :1553
Dimethyldioxirane reacts rapidly at room temperature in acetone with a variety of furans, furnishing in high yield products of oxidative ring opening and, with 2-furanmethanol, 2H-pyran-3(6H)-one via subsequent ring closure.
Autor:
Brian M. Adger, Richard Young
Publikováno v:
Tetrahedron Letters. 25:5219-5222
The selectivity in the catalytic reduction of nitroarylalkylnitriles with hydrazine and metal catalysts was studied.
Autor:
Brian M. Adger, John Surtees
Publikováno v:
Synthetic Communications. 17:223-227
Inpmmidine 1is a highly potent and selective agonist for histamine receptors.1 The synthesis of inpmnidine and structure activity considerations have recently been described. Inpmmidine also has potential valus for the tEatrnent of catecholamine-inse
Autor:
BRIAN M. ADGER, STEVEN BRADBURY, MARTIN KEATING, CHARLES W. REES, RICHARD C. STORR, MICHAEL T. WILLIAMS
Publikováno v:
Chemischer Informationsdienst. 6
Autor:
Brian M. Adger, John Surtees
Publikováno v:
ChemInform. 18
Inpmmidine 1is a highly potent and selective agonist for histamine receptors.1 The synthesis of inpmnidine and structure activity considerations have recently been described. Inpmmidine also has potential valus for the tEatrnent of catecholamine-inse