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pro vyhledávání: '"Brian M Reid"'
Autor:
Richard Wynn, Swamy Yeleswaram, Eddy W. Yue, Gregory Hollis, Nancy Taylor, Padmaja Polam, Paul J. Ala, Zelda Wasserman, Andrew P. Combs, Dawn Ellis, Richard B. Sparks, Wenyu Zhu, Amy Takvorian, Michael J. Bower, Brian M Reid, Phillip Liu, Lucie Gonneville, Timothy Burn, Min Wei, Erin McLaughlin, Mark Rupar, Thomas Emm, Brian Metcalf, Matthew L. Crawley, Dilip P. Modi, Yanlong Li, Brian M. Glass
Publikováno v:
Journal of medicinal chemistry. 49(13)
Potent nonpeptidic benzimidazole sulfonamide inhibitors of protein tyrosine phosphatase 1B (PTP1B) were derived from the optimization of a tripeptide containing the novel (S)-isothiazolidinone ((S)-IZD) phosphotyrosine (pTyr) mimetic. An X-ray cocrys