Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brian M Debo"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158687 (2016)
In this study, we characterized the glycome of cervical-vaginal fluid, collected with a Catamenial cup. We quantified: glycosidase levels; sialic acid and high mannose specific lectin binding; mucins, MUC1, MUC4, MUC5AC, MUC7; and albumin in the samp
Externí odkaz:
https://doaj.org/article/70414cede4944fc38a1864130eddb59d
Autor:
Bernard J Moncla, Catherine A Chappell, Lara K Mahal, Brian M Debo, Leslie A Meyn, Sharon L Hillier
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127091 (2015)
The objective of this study was to evaluate the impact of hormonal status and bacterial vaginosis (BV) on the glycosidases present and glycosylation changes as assessed by lectin binding to cervicovaginal lavage constituents. Frozen cervicovaginal la
Externí odkaz:
https://doaj.org/article/3b915f33aae840de9c5fdfd5a98dc10f
Publikováno v:
Genome Research. 33:427-434
Low-level DNAN6-methyldeoxyadenosine (DNA-m6A) has recently been reported across various eukaryotes. Although anti-m6A antibody–based approaches are commonly used to measure DNA-m6A levels, this approach is known to be confounded by DNA secondary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::850c5b040ee8b448957c61550f0280e8
https://doi.org/10.1101/gr.276696.122
https://doi.org/10.1101/gr.276696.122
The detection of low-abundance DNA N6-methyladenine (DNA-m6A) remains challenging, limiting our understanding of this novel base in eukaryotes. To address this, we introduce an approach for systematically validating the selectivity and sensitivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24666ee5125228963cfd63adb3645a1e
https://doi.org/10.1101/2022.03.02.482749
https://doi.org/10.1101/2022.03.02.482749
Autor:
Connor J. Kenny, Ellen M DeGennaro, Andrew B. Stergachis, Lariza M. Rento, Marc Beaudin, M. Aurel Nagy, Peter P. Wang, Kelly M. Girskis, Taehwan Shin, Michael E. Greenberg, Elizabeth A. Pollina, Peter V. Kharchenko, Ryan N. Doan, Julia L. Scotellaro, Xuyu Qian, Nenad Sestan, Jean Fan, Brian M. Debo, Janet H.T. Song, Dilenny M. Gonzalez, André M. M. Sousa, Rebecca C. Yeh, Christopher A. Walsh, Matthew B. Johnson, Gabrielle M. Sejourne
Publikováno v:
Neuron. 109(20)
Summary Human accelerated regions (HARs) are the fastest-evolving regions of the human genome, and many are hypothesized to function as regulatory elements that drive human-specific gene regulatory programs. We interrogate the in vitro enhancer activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec719659af0fbbd154432819136f29cc
https://pubmed.ncbi.nlm.nih.gov/34672980
https://pubmed.ncbi.nlm.nih.gov/34672980
Autor:
Brian M. Debo, John A. Stamatoyannopoulos, Andrew B. Stergachis, L. Stirling Churchman, Eric Haugen
Publikováno v:
Science (New York, N.Y.). 368(6498)
Primary architecture of chromatin fibers The organization of chromosomal DNA, including the positioning of nucleosomes and nucleosome-free regions harboring regulatory proteins along single chromatin fibers, is fundamental to genome function. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf9a5441b46c5aef402e63ca0bfdb53
https://pubmed.ncbi.nlm.nih.gov/32587015
https://pubmed.ncbi.nlm.nih.gov/32587015
Autor:
Maya Capelson, Kyoung J. Won, Jessica A. Talamas, Yemin Lan, Brian M. Debo, Jennifer R. Aleman, Pau Pascual-Garcia, Nha Nguyen
Publikováno v:
Molecular Cell. 66:63-76.e6
Nuclear pore complex components (Nups) have been implicated in transcriptional regulation, yet what regulatory steps are controlled by metazoan Nups remains unclear. We identified the presence of multiple Nups at promoters, enhancers, and insulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f38f25ea4f64245ad3da519f280479
https://doi.org/10.1016/j.molcel.2017.02.020
https://doi.org/10.1016/j.molcel.2017.02.020