Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Brian L. Strauss"'
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 1, Pp 7-14 (2008)
The JAK/STAT pathway is important for cellular metabolism. One component, STAT5a, is activated in the breast upon prolactin to prolactin receptor (PRLR) binding facilitating the transcription of genes involved in lobule development. STAT5a was previo
Externí odkaz:
https://doaj.org/article/ea60e0642bbf4388bbfdb7c49efbdac8
Publikováno v:
Human Pathology. 37:586-592
The 7 signal transducer and activator of transcription (STAT) molecules are responsible for the transcription of a variety of regulatory and differentiation proteins. STAT 5a is activated through a variety of mechanisms; in the breast, this is predom
Publikováno v:
Histopathology. 47:611-616
Aims : The nuclear detection of p63 in myoepithelial cells of the breast has been useful in identifying possibly invasive carcinomas. While examining myoepithelial cells for p63 a very strong cytoplasmic reaction product was noted in secretory cells.
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 12:266-270
The liquid-phase polymerase chain reaction (PCR) technique is the most commonly used method for the amplification of genetic materials, although it requires the lysis of cells for DNA or RNA extraction, making it impossible to visualize the distribut
Autor:
Kris M. Shekitka, Tuyethoa N. Vinh, Jeffrey S. Saenger, Lisa Tai, Gary L. Bratthauer, Yan Gao Man, Chang Y. Liang, Russell Vang, Darren T Wheeler, Brian L. Strauss, Ross Barner
Publikováno v:
Breast Cancer Research
Introduction Our previous studies detected focal disruptions in myoepithelial cell layers of several ducts with carcinoma in situ. The cell cluster overlying each of the myoepithelial disruptions showed a marked reduction in or a total loss of immuno
Autor:
Bernard Gonik, Abraham Hochberg, Ran Goshen, Jacob Rachmilewitz, Michael Elkin, Haim Giloh, Zvi Neaman, Brian L. Strauss, Nathan de Groot, D. Komitowsky
Publikováno v:
Gynecologic Oncology. 57:356-365
Previous experiments demonstrated that human cytotrophoblasts and cells of the choriocarcinoma cell line JAr interact in vitro. As a result of this interaction there is an increased synthesis of CG and hPL, probably as a result of the increased CG an
Publikováno v:
Journal of Biological Chemistry. 269:4968-4973
Transcriptional activation of the chorionic gonadotropin (CG) genes is linked to trophoblast differentiation. In a multistep process, cytotrophoblasts expressing only the alpha subunit differentiate into intermediates that coexpress the CG beta subun
Publikováno v:
Journal of Biological Chemistry. 266:8517-8522
The human placenta arises from the zygote through single cell intermediates called cytotrophoblasts that in turn give rise to a syncytium. In culture, mononucleated cytotrophoblasts exhibit little, if any, cell division but are converted to multinucl
Publikováno v:
Virchows Archiv : an international journal of pathology. 448(2)
The seven signal transducer and activator of transcription (STAT) molecules are effectors of hormonal or cytokine stimulation through receptors. STAT 5a, isolated from prolactin-stimulated mammary cells, contributes to normal proliferation and is ess
Autor:
Ting Shen, Yan Gao Man, Jordi Tauler, Brian L. Strauss, Yi Zhang, Xiao Zeng, James L. Mulshine
Publikováno v:
Breast cancer research and treatment. 89(2)
Background. Our previous studies revealed that a subset of mammary ductal carcinoma in situ (DCIS) contained focally disrupted myoepithelial (ME) cell layers that were predominantly overlain by estrogen receptor (ER) negative cells, which showed a su