Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Brian L. Largent"'
Autor:
Lawrence W. Fitzgerald, Carol M. Krause, Anne P. Marshall, John P. Patterson, Deborah S. Conklin, Geeta Iyer, David P. Tran, Brian L. Largent, Paul R. Hartig, Walter A. Kostich
Publikováno v:
Journal of Neurochemistry. 72:2127-2134
Many modern models of receptor-G protein function assume that there is a direct relationship between high-affinity agonist binding and efficacy. The validity of this assumption has been recently questioned for the serotonin 5-HT2A receptor. We examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defe1bccc985bc020be71199c2f61751
https://doi.org/10.1046/j.1471-4159.1999.0722127.x
https://doi.org/10.1046/j.1471-4159.1999.0722127.x
Publikováno v:
The Journal of Comparative Neurology. 478:111-125
Corticotropin-releasing factor receptor type 1, CRF1, plays a prominent role in the hypothalamic-pituitary-adrenal (HPA) axis and is implicated in the autonomic and behavioral responses to stress. Dysregulation of the CRF system may underlie the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e873bad82cf578112dc941eafd73a82b
https://doi.org/10.1002/cne.20271
https://doi.org/10.1002/cne.20271
Autor:
Leah A. Breth, Alan K. Robbins, Emily S. Shen, Karen Sperle, Brian L. Largent, Christian C. Reid, Gary M. Cooke, Robert A. Horlick
Publikováno v:
Protein Expression and Purification. 9:301-308
Human HEK293 cells that stably express the Epstein Barr nuclear antigen 1 (EBNA1) support the episomal replication of plasmids containing the Epstein Barr virus origin of replication (EBV oriP). A 293EBNA (293E) cell line expressing the human cortico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b02f86a5ebf9e638b1752886c421461
https://doi.org/10.1006/prep.1996.0701
https://doi.org/10.1006/prep.1996.0701
Publikováno v:
Developmental Genetics. 20:208-223
Members of the Notch gene family are thought to be involved in the regulation of cell fate decisions in a variety of embryonic tissues, particularly in the developing central nervous system (CNS) in Drosophila and vertebrates. In goldfish the CNS con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27e1a135b9d103339ba34b2db80e2e9
https://doi.org/10.1002/(sici)1520-6408(1997)20:3<208::aid-dvg4>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1997)20:3<208::aid-dvg4>3.0.co
Publikováno v:
Neuron. 11:387-400
Tyrosine phosphorylation plays a central role in the control of neuronal cell development and function. Yet, few neuronal protein tyrosine phosphatases (PTPs) have been identified. We examined rat olfactory neuroepithelium for expression of novel PTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff128d20df46e2ba1360839478edc8eb
https://doi.org/10.1016/0896-6273(93)90193-u
https://doi.org/10.1016/0896-6273(93)90193-u
Publikováno v:
Monoaminergic Modulation of Cortical Excitability ISBN: 9780387722542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8de003874bfc2823311c80db1d7e1f96
https://doi.org/10.1007/978-0-387-72256-6_2
https://doi.org/10.1007/978-0-387-72256-6_2
Autor:
Cecilia L. Chi, Kenneth W. Rohrbach, Brian L. Largent, Songping Han, Eva O’Tanyi, Jinping Gan, Dong Cheng, Hongwei Zhang, Rebecca Taub
Publikováno v:
European journal of pharmacology. 511(1)
In order to explore the relationship between the anorectic effect of 3-carboxy-4-octyl-2-methylenebutyrolactone (C75) and its pharmacokinetic properties, studies of in vivo and in vitro pharmacological characterization of C75 were performed in Fische
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5cf965dd42c4527270c0b52a1a829a
https://pubmed.ncbi.nlm.nih.gov/15777777
https://pubmed.ncbi.nlm.nih.gov/15777777
Autor:
Albert J. Robichaud, Lee Taekyu, John F. McElroy, Yimin Lu, Larry W. Fitzgerald, Keith J. Miller, Kristopher E. Boyle, David W. Robertson, Brian L. Largent
Publikováno v:
ChemInform. 34
The discovery of N-substituted-pyridoindolines and their binding affinities at the 5-HT(2A), 5-HT(2C) and D(2) receptors, and in vivo efficacy as 5-HT(2A) antagonists is described. The structure-activity relationship of a series of core tetracyclic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a39140b59f99461fad8d99b9e97c714
https://doi.org/10.1002/chin.200324140
https://doi.org/10.1002/chin.200324140
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 12(8)
We report the discovery of a new CRF2 receptor splice isoform found in human brain, which we have termed the CRF2gamma receptor. The CRF2gamma cDNA encodes for a 397-amino acid receptor that has an amino terminus with no significant homology to the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb3a1d07c20942cbe0bb60c79e4ce37
https://pubmed.ncbi.nlm.nih.gov/9717834
https://pubmed.ncbi.nlm.nih.gov/9717834