Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Brian L Grills"'
Publikováno v:
Advances in Physiology Education. 45:281-289
Expert educators in science argue that science graduates are often lacking skills in effectively communicating scientific information to lay audiences. To address this, we designed a project, Communicating Disease, for final-year undergraduate human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba170b9c60ada381c1c81a7b237fbef
https://doi.org/10.1152/advan.00016.2020
https://doi.org/10.1152/advan.00016.2020
Autor:
Maddison R, Johnstone, Rhys D, Brady, Jarrod E, Church, David, Orr, Stuart J, McDonald, Brian L, Grills
Publikováno v:
Journal of Musculoskeletal & Neuronal Interactions
Objectives: To study the effects of the selective TrkB agonist, 7,8-dihydroxyflavone (7,8-DHF), on fracture healing in mice and on an osteoprogenitor cell line, Kusa4b10, in vitro. Methods: Mice received unilateral closed mid-shaft tibial fractures a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f05106eb8381ed7d9caafa73744e2391
https://pubmed.ncbi.nlm.nih.gov/34059571
https://pubmed.ncbi.nlm.nih.gov/34059571
Autor:
Mujun Sun, Stuart J. McDonald, Brian L Grills, Rhys D. Brady, Caroline J. Taylor, Maddison R Johnstone, Sandy R. Shultz, Jarrod E Church
Publikováno v:
Brain Injury. 32:257-268
Objectives There is evidence that treatment with nerve growth factor (NGF) may reduce neuroinflammation and apoptosis after a traumatic brain injury (TBI). NGF is thought to exert its effects via binding to either TrkA or p75 neurotrophin receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20e16122b7dbe85aef68713ec0b9c50
https://doi.org/10.1080/02699052.2017.1394492
https://doi.org/10.1080/02699052.2017.1394492
Publikováno v:
Journal of Cellular Physiology. 233:2133-2145
Neurotrophins and their receptors are key molecules that are known to be critical in regulating nervous system development and maintenance and have been recognized to be also involved in regulating tissue formation and healing in skeletal tissues. St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691a8f8b74a48fc7ae8f3fed875ce788
https://doi.org/10.1002/jcp.25936
https://doi.org/10.1002/jcp.25936
Autor:
Nishanthi, Mathiyalagan, Lee B, Miles, Peter J, Anderson, Tomasz, Wilanowski, Brian L, Grills, Stuart J, McDonald, M Cristina, Keightley, Agata, Charzynska, Michal, Dabrowski, Sebastian, Dworkin
Publikováno v:
Genes
The Drosophila grainyhead (grh) and vertebrate Grainyhead-like (Grhl) transcription factors are among the most critical genes for epithelial development, maintenance and homeostasis, and are remarkably well conserved from fungi to humans. Mutations a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ada45edcebd95030f264d28d403bca67
https://pubmed.ncbi.nlm.nih.gov/31683705
https://pubmed.ncbi.nlm.nih.gov/31683705
Autor:
John D. Wark, Stuart J. McDonald, Rhys D. Brady, Kristina Anevska, Jessica F. Briffa, Tania Romano, Dayana Mahizir, Brian L Grills, Andrew J. Jefferies, Mary E. Wlodek
Publikováno v:
Nutrients, Vol 11, Iss 6, p 1236 (2019)
Nutrients
Volume 11
Issue 6
Nutrients
Volume 11
Issue 6
Growth restriction programs adult bone deficits and increases the risk of obesity, which may be exacerbated during pregnancy. We aimed to determine if high-fat feeding could exacerbate the bone deficits in pregnant growth restricted dams, and whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2707b3e138b6360ff56082db86f36ece
https://www.mdpi.com/2072-6643/11/6/1236
https://www.mdpi.com/2072-6643/11/6/1236
Autor:
Maddison R, Johnstone, Rhys D, Brady, Johannes A, Schuijers, Jarrod E, Church, David, Orr, Julian M W, Quinn, Stuart J, McDonald, Brian L, Grills
Publikováno v:
Journal of Musculoskeletal & Neuronal Interactions
Objectives: To study effects of the selective TrkA agonist, gambogic amide (GA), on fracture healing in mice and on an osteoprogenitor cell line in vitro. Methods: Mice were given bilateral fibular fractures and treated for two weeks with vehicle or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48fa5c77321871d824f6a1cf5586df20
https://pubmed.ncbi.nlm.nih.gov/30839307
https://pubmed.ncbi.nlm.nih.gov/30839307
Autor:
Terence J. O'Brien, Peter Vee Sin Lee, Pablo M. Casilla-Espinosa, Mujun Sun, Richelle Mychasiuk, Dale L. Robinson, Stuart J. McDonald, Glenn R. Yamakawa, Michael Z. Zhao, Brian L Grills, Rhys D. Brady, Sandy R. Shultz, Ker R. Wong, Ryan C. Wortman, Denes V. Agoston
Publikováno v:
Bone. 133:115263
Neurological heterotopic ossification (NHO) is characterized by abnormal bone growth in soft tissue and joints in response to injury to the central nervous system. The ectopic bone frequently causes pain, restricts mobility, and decreases the quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23509102a8ec9ced42446193d0fa97b3
https://doi.org/10.1016/j.bone.2020.115263
https://doi.org/10.1016/j.bone.2020.115263
Autor:
Julian Michael Warner Quinn, Jason M. Hodge, Preetinder P. Singh, Matthew T. Gillespie, Damien Eeles, Johannes A. Schuijers, Damian E. Myers, Brian L Grills
Publikováno v:
Molecular and Cellular Endocrinology. 399:259-266
Osteoclasts are bone resorbing multinucleated cells (MNCs) derived from macrophage progenitors. IL-33 has been reported to drive osteoclastogenesis independently of receptor activator of NFκB ligand (RANKL) but this remains controversial as later st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62229516a453fb4dca1cb72414cc453
https://doi.org/10.1016/j.mce.2014.10.014
https://doi.org/10.1016/j.mce.2014.10.014
Autor:
Johannes A. Schuijers, Alex R. Ward, Brett A. Tonkin, Stuart J. McDonald, Nicole C. Walsh, Rhys D. Brady, Brian L Grills
Publikováno v:
Journal of Orthopaedic Research. 32:1277-1282
Thymosin β4 (Tβ4 ) is a regenerative peptide that we hypothesized would promote healing of fractured bone. Mice received a bilateral fibular osteotomy and were given i.p. injections of either Tβ4 (6 mg/kg) or saline. Calluses from saline- and Tβ4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca866aa57aa39c20553b505658950ac
https://doi.org/10.1002/jor.22686
https://doi.org/10.1002/jor.22686