Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Brian L, Lee"'
Autor:
Tanvir Sajed, Zinat Sayeeda, Brian L. Lee, Mark Berjanskii, Fei Wang, Vasuk Gautam, David S. Wishart
Publikováno v:
Metabolites, Vol 14, Iss 5, p 290 (2024)
NMR is widely considered the gold standard for organic compound structure determination. As such, NMR is routinely used in organic compound identification, drug metabolite characterization, natural product discovery, and the deconvolution of metaboli
Externí odkaz:
https://doaj.org/article/033a58af5ec043b8bb041fbb5f5c35de
Autor:
Sara Seager, Janusz J. Petkowski, Maxwell D. Seager, John H. Grimes, Zachary Zinsli, Heidi R. Vollmer-Snarr, Mohamed K. Abd El-Rahman, David S. Wishart, Brian L. Lee, Vasuk Gautam, Lauren Herrington, William Bains, Charles Darrow
Publikováno v:
Life, Vol 14, Iss 5, p 538 (2024)
We show that the nucleic acid bases adenine, cytosine, guanine, thymine, and uracil, as well as 2,6-diaminopurine, and the “core” nucleic acid bases purine and pyrimidine, are stable for more than one year in concentrated sulfuric acid at room te
Externí odkaz:
https://doaj.org/article/a3260439f65f43399e9421d460304ffa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract The ubiquitin proteasome system (UPS) signals for degradation of proteins through attachment of K48-linked polyubiquitin chains, or alterations in protein-protein recognition through attachment of K63-linked chains. Target proteins are ubiqu
Externí odkaz:
https://doaj.org/article/847413dcf7314bdbbe3d72508e66203f
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 383-395 (2018)
Summary: Ring1-YY1-binding protein (RYBP) is a member of the non-canonical polycomb repressive complex 1 (PRC1), and like other PRC1 members, it is best described as a transcriptional regulator. However, several PRC1 members were recently shown to fu
Externí odkaz:
https://doaj.org/article/fb30547d2923417a8d14199a8aae6f6e
Autor:
David S. Wishart, Raynard Dizon, Mickel Hiebert-Giesbrecht, Eponine Oler, An Chi Guo, Andrew Maras, Mark V. Berjanskii, Manoj Kumar Rout, John R. Cort, Victoria Sullivan, Saurav J. Sarma, Zachary Budinski, Dorna Varshavi, Brian L. Lee, Jeffrey A. van Santen, Zinat Sayeeda, Claudia Torres-Calzada, Pegah Tavangar, Lloyd W. Sumner, Roger G. Linington, Ryan S. Renslow, Xuan Cao, Rajarshi Ghosh, Robert Mah, Harrison Peters, Ella F. Poynton, Vera Yang, Eleanor Knutson, Amy M Jystad, Vasuk Gautam, Dana Allen, Dorsa Varshavi
Publikováno v:
Nucleic Acids Research
The Natural Products Magnetic Resonance Database (NP-MRD) is a comprehensive, freely available electronic resource for the deposition, distribution, searching and retrieval of nuclear magnetic resonance (NMR) data on natural products, metabolites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528422e8859ef89cb9fc542a4d3a5104
https://doi.org/10.1093/nar/gkab1052
https://doi.org/10.1093/nar/gkab1052
Autor:
David S, Wishart, Manoj, Rout, Brian L, Lee, Mark, Berjanskii, Marcia, LeVatte, Matthias, Lipfert
Publikováno v:
Handbook of experimental pharmacology.
While NMR-based metabolomics is only about 20 years old, NMR has been a key part of metabolic and metabolism studies for40 years. Historically, metabolic researchers used NMR because of its high level of reproducibility, superb instrument stability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::033f3b7d0a1ccfc89630570d1b29fafe
https://pubmed.ncbi.nlm.nih.gov/36271165
https://pubmed.ncbi.nlm.nih.gov/36271165
Publikováno v:
The Journal of Physical Chemistry B. 124:2984-2993
Protein turnover in cells is regulated by the ATP dependent activity of the Hsp90 chaperone. In concert with accessory proteins, ATP hydrolysis drives the obligate Hsp90 dimer through a cycle betwe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf91d7943b34979e832a96c8a0e7494
https://doi.org/10.1021/acs.jpcb.0c00626
https://doi.org/10.1021/acs.jpcb.0c00626
Autor:
David S. Wishart, Manoj Rout, Brian L. Lee, Mark Berjanskii, Marcia LeVatte, Matthias Lipfert
Publikováno v:
Metabolomics and Its Impact on Health and Diseases ISBN: 9783031268588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a8b7db7f2a9ee55bb3f25ff6b060c6
https://doi.org/10.1007/164_2022_613
https://doi.org/10.1007/164_2022_613
Autor:
David S Wishart, AnChi Guo, Eponine Oler, Fei Wang, Afia Anjum, Harrison Peters, Raynard Dizon, Zinat Sayeeda, Siyang Tian, Brian L Lee, Mark Berjanskii, Robert Mah, Mai Yamamoto, Juan Jovel, Claudia Torres-Calzada, Mickel Hiebert-Giesbrecht, Vicki W Lui, Dorna Varshavi, Dorsa Varshavi, Dana Allen, David Arndt, Nitya Khetarpal, Aadhavya Sivakumaran, Karxena Harford, Selena Sanford, Kristen Yee, Xuan Cao, Zachary Budinski, Jaanus Liigand, Lun Zhang, Jiamin Zheng, Rupasri Mandal, Naama Karu, Maija Dambrova, Helgi B Schiöth, Russell Greiner, Vasuk Gautam
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 50(D1), D622-D631
Nucleic Acids Research, 50(D1), D622-D631
The Human Metabolome Database or HMDB (https://hmdb.ca) has been providing comprehensive reference information about human metabolites and their associated biological, physiological and chemical properties since 2007. Over the past 15 years, the HMDB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fe74ccb13c2d2c47ecad7d0207b7d7
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-467455
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-467455
Publikováno v:
The Journal of Physical Chemistry B. 123:3665-3671
19F NMR spectroscopy is a powerful tool for the study of the structures, dynamics, and interactions of proteins bearing cysteine residues chemically modified with a trifluoroacetone group (CYF residue). 19F NMR relaxation rates for the fluoromethyl g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238c6ced5b8454638daf65149ef78db1
https://doi.org/10.1021/acs.jpcb.9b01741
https://doi.org/10.1021/acs.jpcb.9b01741