Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Brian K. Lohman"'
Autor:
Zhesen Tan, Chi Ho Chan, Michael Maleska, Bryan Banuelos Jara, Brian K. Lohman, Nathan J. Ricks, Daniel R. Bond, Ming C. Hammond
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1183 (2022)
The Hypr cGAMP signaling pathway was discovered via the function of the riboswitch. In this study, we show the development of a method for affinity capture followed by sequencing to identify non-coding RNA regions that bind nucleotide signals such as
Externí odkaz:
https://doaj.org/article/1cff22fe4f024d8083608754276cfd04
Autor:
Jesse N. Weber, Natalie C. Steinel, Foen Peng, Kum Chuan Shim, Brian K. Lohman, Lauren E. Fuess, Swapna Subramanian, Stephen P. De Lisle, Daniel I. Bolnick
Publikováno v:
Science
Parasites impose fitness costs on their hosts. Biologists often assume that natural selection favors infection-resistant hosts. Yet, when the immune response itself is costly, theory suggests that selection may sometimes favor loss of resistance, whi
Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner
Autor:
Kate M. Warde, Lorenzo J. Smith, Lihua Liu, Chris J. Stubben, Brian K. Lohman, Parker W. Willett, Julia L. Ammer, Guadalupe Castaneda-Hernandez, Sikiru O. Imodoye, Chenge Zhang, Kara D. Jones, Kimber Converso-Baran, H. Atakan Ekiz, Marc Barry, Michael R. Clay, Katja Kiseljak-Vassiliades, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Publikováno v:
Nature Aging.
Autor:
Spyros Darmanis, Laurence S. Baskin, Brian K. Lohman, Robert L. Judson-Torres, Ursula E. Lang, Rachel L. Belote, Vicente Planells-Palop, Ashley Maynard, Daniel D. Le, Adriane Sinclair, Aaron D. Tward
Publikováno v:
Nature Cell Biology. 23:1035-1047
In humans, epidermal melanocytes are responsible for skin pigmentation, defence against ultraviolet radiation and the deadliest common skin cancer, melanoma. Although there is substantial overlap in melanocyte development pathways between different m
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Heritable population differences in immune gene expression following infection can reveal mechanisms of host immune evolution. We compared gene expression in infected and uninfected threespine stickleback (Gasterosteus aculeatus) from two natural pop
Externí odkaz:
https://doaj.org/article/b5d00885cd6a40d0b75585d8f351d5b4
A phospho-tyrosine-based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity
Autor:
Kazuki Tawaratsumida, Vanessa Redecke, Ruiqiong Wu, Jeeba Kuriakose, Jill J. Bouchard, Tanja Mittag, Brian K. Lohman, Ashutosh Mishra, Anthony A. High, Hans Häcker
Publikováno v:
Science advances. 8(27)
Toll-like receptors (TLRs) recognize pathogen- and host-derived factors and control immune responses via the adaptor protein MyD88 and members of the interferon regulatory transcription factor (IRF) family. IRFs orchestrate key effector functions, in
Senescence-Induced Immune Remodeling Facilitates Metastatic Adrenal Cancer in a Sex-Dimorphic Manner
Autor:
Kate M. Warde, Lihua Liu, Lorenzo J. Smith, Brian K. Lohman, Chris J. Stubben, H. Atakan Ekiz, Julia L. Ammer, Kimber Converso-Baran, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Aging is a carcinogen that markedly increases cancer risk, yet we have limited mechanistic understanding of cancer initiation in aged cells. Here, we demonstrate induction of the hallmark aging process cellular senescence, triggered by loss of Wnt in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cfadeccc109b321b91df3229686702
https://doi.org/10.1101/2022.04.29.488426
https://doi.org/10.1101/2022.04.29.488426
Autor:
Shannon R. McCurdy, Elizabeth D. Thompson, Djamilatou Adom, Brian K. Lohman, Jonathan D. Powell, Ante Vulic, Vedran Radojcic, Richard J. Jones, Ravi Varadhan, Kenneth R. Cooke, Leo Luznik, Sanja Ivčević, Hua-Ling Tsai, Christopher G. Kanakry, Sophie Paczesny, Heather J. Symons
Publikováno v:
Blood
The key immunologic signatures associated with clinical outcomes after posttransplant cyclophosphamide (PTCy)-based HLA-haploidentical (haplo) and HLA-matched bone marrow transplantation (BMT) are largely unknown. To address this gap in knowledge, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8709a44fdf761b87477c6e63c0527b9
https://europepmc.org/articles/PMC8796655/
https://europepmc.org/articles/PMC8796655/
Autor:
Zhesen, Tan, Chi Ho, Chan, Michael, Maleska, Bryan, Banuelos Jara, Brian K, Lohman, Nathan J, Ricks, Daniel R, Bond, Ming C, Hammond
Publikováno v:
International journal of molecular sciences. 23(3)
The Hypr cGAMP signaling pathway was discovered via the function of the riboswitch. In this study, we show the development of a method for affinity capture followed by sequencing to identify non-coding RNA regions that bind nucleotide signals such as
Autor:
Daniel I. Bolnick, S. De Lisle, Lauren E. Fuess, Foen Peng, Natalie C. Steinel, Jesse N. Weber, Kum Chuan Shim, Brian K. Lohman
Parasites impose fitness costs on their hosts. Biologists therefore tend to assume that natural selection favors infection-resistant hosts. Yet, when the immune response itself is costly, theory suggests selection may instead favor loss of resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab54ec33a1db03b16179dea2eb8aa13
https://doi.org/10.1101/2021.08.04.455160
https://doi.org/10.1101/2021.08.04.455160