Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Brian K. Janes"'
Publikováno v:
PLoS ONE, Vol 5, Iss 8 (2010)
Externí odkaz:
https://doaj.org/article/ff2e61f8799c44e1bdb570d140ba8739
Publikováno v:
Molecular Microbiology. 84:370-382
Summary In Bacillus anthracis the siderophore petrobactin is vital for iron acquisition and virulence. The petrobactin-binding receptor FpuA is required for these processes. Here additional components of petrobactin reacquisition are described. To id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7eccbf7c3685ca701cd5efa0368093
https://doi.org/10.1111/j.1365-2958.2012.08028.x
https://doi.org/10.1111/j.1365-2958.2012.08028.x
Publikováno v:
Journal of Bacteriology. 192:4834-4846
The nitrogen assimilation control protein (NAC) from Klebsiella pneumoniae is a typical LysR-type transcriptional regulator (LTTR) in many ways. However, the lack of a physiologically relevant coeffector for NAC and the fact that NAC can carry out ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd479cfb7cb719014862c4a8539f125
https://doi.org/10.1128/jb.01114-09
https://doi.org/10.1128/jb.01114-09
Autor:
Philip C. Hanna, Shandee D. Dixon, Tyler D. Nusca, Sarra E. Keene, Erica C. Anderson, Katherine A. Carr, David H. Sherman, Paul E. Carlson, Brian K. Janes
Publikováno v:
Molecular Microbiology. 75:900-909
Iron acquisition mechanisms play an important role in the pathogenesis of many infectious microbes. In Bacillus anthracis, the siderophore petrobactin is required for both growth in iron-depleted conditions and for full virulence of the bacterium. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaed3ddaedc1059656d7fcf7cc32170
https://doi.org/10.1111/j.1365-2958.2009.07025.x
https://doi.org/10.1111/j.1365-2958.2009.07025.x
Autor:
Brian F. Pfleger, Erica C. Anderson, Jamie B. Scaglione, Tyler D. Nusca, Christopher M. Rath, David H. Sherman, Philip C. Hanna, Nicholas H. Bergman, Youngchang Kim, Natalia Maltseva, Andrzej Joachimiak, Jung Yeop Lee, Brian K. Janes
Publikováno v:
Proceedings of the National Academy of Sciences. 105:17133-17138
Petrobactin, a virulence-associated siderophore produced by Bacillus anthracis , chelates ferric iron through the rare 3,4-isomer of dihydroxybenzoic acid (3,4-DHBA). Most catechol siderophores, including bacillibactin and enterobactin, use 2,3-DHBA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97acc5c45f80011db8acc91b60232941
https://doi.org/10.1073/pnas.0808118105
https://doi.org/10.1073/pnas.0808118105
Autor:
Ravindranadh V. Somu, Courtney C. Aldrich, Philip C. Hanna, Brian K. Janes, Haichuan Liu, David H. Sherman, Brian F. Pfleger, Kristina Håkansson, Karla D. Passalacqua, Jung Yeop Lee, Nicholas H. Bergman, Stephen R. Cendrowski
Publikováno v:
Journal of Bacteriology. 189:1698-1710
The asbABCDEF gene cluster from Bacillus anthracis is responsible for biosynthesis of petrobactin, a catecholate siderophore that functions in both iron acquisition and virulence in a murine model of anthrax. We initiated studies to determine the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12bd0524573e5a5328859624df5b3f1
https://doi.org/10.1128/jb.01526-06
https://doi.org/10.1128/jb.01526-06
Autor:
Dominika Chalupska, Keith D. Green, Philip C. Hanna, Brian K. Janes, Sylvie Garneau-Tsodikova, Andrzej Joachimiak, Wei Chen, Ruiying Wu, Tapan Biswas, Oleg V. Tsodikov, Changsoo Chang, Piotr Gornicki
Publikováno v:
Biochemistry. 54(20)
Proteins from the enhanced intracellular survival (Eis) family are versatile acetyltransferases that acetylate amines at multiple positions of several aminoglycosides (AGs). Their upregulation confers drug resistance. Homologues of Eis are present in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eec32d7cd8da30d60e071e9cd42b94d
https://pubmed.ncbi.nlm.nih.gov/25928210
https://pubmed.ncbi.nlm.nih.gov/25928210
Publikováno v:
Journal of Bacteriology. 185:688-692
A negative control mutant of the nitrogen assimilation control protein, NAC, has been isolated. Mutants with the leucine at position 111 changed to a nonhydrophobic residue activate transcription from hut and ure promoters, but fail to repress gdhA e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4dabec4941509bb7a8a90394efc9990
https://doi.org/10.1128/jb.185.2.688-692.2003
https://doi.org/10.1128/jb.185.2.688-692.2003
Autor:
Thomas J. Goss, Pablo J. Pomposiello, David J. Najarian, Ana Perez-Matos, Brian K. Janes, Robert A. Bender
Publikováno v:
Journal of Bacteriology. 183:2709-2714
Two linked mutations affecting glutamate dehydrogenase (GDH) formation ( gdh-1 and rev-2 ) had been isolated at a locus near the trp cluster in Klebsiella aerogenes . The properties of these two mutations were consistent with those of a locus contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4909a3cd197a978610ec0b76d1b67cb
https://doi.org/10.1128/jb.183.8.2709-2714.2001
https://doi.org/10.1128/jb.183.8.2709-2714.2001
Autor:
Robert A. Bender, Brian K. Janes
Publikováno v:
Journal of Bacteriology. 180:563-570
Klebsiella aerogenes strains with reduced levels of d -amino acid dehydrogenase not only fail to use alanine as a growth substrate but also become sensitive to alanine in minimal media supplemented with glucose and ammonium. The inability of these mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9a5241df33ba09c6ff8cc72d13caa8
https://doi.org/10.1128/jb.180.3.563-570.1998
https://doi.org/10.1128/jb.180.3.563-570.1998