Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brian K. Buckley"'
Publikováno v:
J Mol Cell Cardiol
Rationale Collateral vessels lessen myocardial ischemia when acute or chronic coronary obstruction occurs. It has long been assumed that although native (pre-existing) collaterals enlarge in obstructive disease, new collaterals do not form in the adu
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:3544-3555
Variation in extent of the brain’s collateral circulation is an important determinant of variation in the severity of stroke and efficacy of revascularization therapies. However, the number and diameter of pial collateral “arterioles” decrease
Autor:
Lin Xiao, Robert Sealock, Jennifer L. Lucitti, Brian K. Buckley, Hua Zhang, Andrew C. Dudley, James E. Faber
Publikováno v:
Stroke. 47:3022-3031
Background and Purpose— The extent (number and diameter) of collateral vessels varies widely and is a major determinant, along with arteriogenesis (collateral remodeling), of variation in severity of tissue injury after large artery occlusion. Diff
Publikováno v:
Stroke. 48
Variation in anatomic extent of the collateral circulation is an important determinant of variation in the severity of ischemic stroke and efficacy of revascularization therapies. Yet pial collateral number and lumen diameter decrease with age, at le
Autor:
Geneviève Laroche, Ejiofor A.D. Ezekwe, Jenny P.-Y. Ting, Justin E. Wilson, B. J. P. Gall, Joseph A. Duncan, Chahnaz Kebaier, Patrick M. Giguère, Brian K. Buckley, David P. Siderovski
Inflammasomes are multi-protein complexes that regulate maturation of the interleukin 1β-related cytokines IL-1β and IL-18 through activation of the cysteine proteinase caspase-1. NOD-like receptor family, pyrin domain containing 3 (NLRP3) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dcf7bbadb6ff9a29903b08c204f5a9
Autor:
Kunjie Hua, James E. Faber, Fernando Pardo-Manuel de Villena, Brian K. Buckley, Scott A. Kelly, Rachel C. McMullan, Daniel Pomp
Publikováno v:
Physiological Reports
Aging is associated with declining exercise and unhealthy changes in body composition. Exercise ameliorates certain adverse age‐related physiological changes and protects against many chronic diseases. Despite these benefits, willingness to exercis
Autor:
M.W. McGinnis, Oded Foreman, Brian K. Buckley, Patrick M. Giguère, Teresa K. Tarrant, Peng Liu, Denise Esserman, Roman G. Timoshchenko, David P. Siderovski, Matthew J. Billard, Geneviève Laroche
Publikováno v:
Molecular immunology. 54(2)
Polymorphism at the GPSM3 gene locus is inversely associated with four systemic autoimmune diseases, including rheumatoid arthritis and ankylosing spondylitis. G-protein signaling modulator-3 (GPSM3) expression is most pronounced in myeloid cells, in
Autor:
Harish Radhakrishna, Vadim Y. Arshavsky, Staci P. Cohen, Robert Tarran, Mickey Kosloff, Adam J. Kimple, David P. Siderovski, Francis S. Willard, Dustin E. Bosch, Michael D. Brown, Gang Cheng, Brian K. Buckley, Alaina L. Garland
The gustatory system detects tastants and transmits signals to the brain regarding ingested substances and nutrients. Although tastant receptors and taste signaling pathways have been identified, little is known about their regulation. Because bitter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbae97aff3ff6a3a14934a5762b3042
https://europepmc.org/articles/PMC3516720/
https://europepmc.org/articles/PMC3516720/
Autor:
Henrik Frydenlund Hansen, Maria A. Graziewicz, Jennifer Roberts, Ryszard Kole, Henrik Ørum, Peter Sazani, Brian K. Buckley, Le Shara M. Fulton, Teresa K. Tarrant
Publikováno v:
Molecular Therapy
Tumor necrosis factor-alpha (TNF-alpha) is a key mediator of inflammatory diseases, including rheumatoid arthritis (RA), and anti-TNF-alpha drugs such as etanercept are effective treatments. Splice-switching oligonucleotides (SSOs) are a new class of