SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients

Autor: Sierk Haenisch, Yi Zhao, Aparna Chhibber, Kitti Kaiboriboon, Lynn V. Do, Silke Vogelgesang, Nicholas M. Barbaro, Brian K. Alldredge, Daniel H. Lowenstein, Ingolf Cascorbi, Deanna L. Kroetz

Publikováno v: Neurobiology of Disease, Vol 77, Iss , Pp 127-140 (2015)

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally control the expression of their target genes via RNA interference. There is increasing evidence that expression of miRNAs is dysregulated in neuronal disorders, including epilep

Externí odkaz: https://doaj.org/article/a5bb73dac40644289e2604a39397ca06

Developing faculty leadership from ‘within’: a 12-year reflection from an internal faculty leadership development program of an academic health sciences center

Autor: Brian K. Alldredge, John W. Barr, Anda K. Kuo, Amin Azzam, Irené Merry, Janice Y. Tsoh, Laney Whitcanack

Publikováno v: Medical Education
Medical education online, vol 24, iss 1
Medical Education Online, Vol 24, Iss 1 (2019)
Tsoh, Janice Y; Kuo, Anda K; Barr, John W; Whitcanack, Laney; Merry, Irené; Alldredge, Brian K; et al.(2019). Developing faculty leadership from 'within': a 12-year reflection from an internal faculty leadership development program of an academic health sciences center.. Medical education online, 24(1), 1567239. doi: 10.1080/10872981.2019.1567239. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/6719z94z

Most academic health sciences centers offer faculty leadership development programs (LDPs); however, the outcomes of LDPs are largely unknown. This article describes perspectives from our 12-year experience cultivating a formal faculty LDP within an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcbd66ef5e9b7305f07a6667fd9cf5d
http://europepmc.org/articles/PMC6366438

De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies

Autor: Silke Appenzeller, Rudi Balling, Nina Barisic, Stéphanie Baulac, Hande Caglayan, Dana Craiu, Peter De Jonghe, Christel Depienne, Petia Dimova, Tania Djémié, Padhraig Gormley, Renzo Guerrini, Ingo Helbig, Helle Hjalgrim, Dorota Hoffman-Zacharska, Johanna Jähn, Karl Martin Klein, Bobby Koeleman, Vladimir Komarek, Roland Krause, Gregor Kuhlenbäumer, Eric Leguern, Anna-Elina Lehesjoki, Johannes R. Lemke, Holger Lerche, Tarja Linnankivi, Carla Marini, Patrick May, Rikke S. Møller, Hiltrud Muhle, Deb Pal, Aarno Palotie, Manuela Pendziwiat, Angela Robbiano, Filip Roelens, Felix Rosenow, Kaja Selmer, Jose M. Serratosa, Sanjay Sisodiya, Ulrich Stephani, Katalin Sterbova, Pasquale Striano, Arvid Suls, Tiina Talvik, Sarah von Spiczak, Yvonne Weber, Sarah Weckhuysen, Federico Zara, Bassel Abou-Khalil, Brian K. Alldredge, Eva Andermann, Frederick Andermann, Dina Amrom, Jocelyn F. Bautista, Samuel F. Berkovic, Judith Bluvstein, Alex Boro, Gregory Cascino, Damian Consalvo, Patricia Crumrine, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Miguel Fiol, Nathan B. Fountain, Jacqueline French, Daniel Friedman, Eric B. Geller, Tracy Glauser, Simon Glynn, Kevin Haas, Sheryl R. Haut, Jean Hayward, Sandra L. Helmers, Sucheta Joshi, Andres Kanner, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rachel Kuperman, Ruben Kuzniecky, Daniel H. Lowenstein, Shannon M. McGuire, Paul V. Motika, Edward J. Novotny, Ruth Ottman, Juliann M. Paolicchi, Jack Parent, Kristen Park, Annapurna Poduri, Lynette Sadleir, Ingrid E. Scheffer, Renée A. Shellhaas, Elliott Sherr, Jerry J. Shih, Rani Singh, Joseph Sirven, Michael C. Smith, Joe Sullivan, Liu Lin Thio, Anu Venkat, Eileen P.G. Vining, Gretchen K. Von Allmen, Judith L. Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer, Andrew S. Allen, Patrick Cossette, Norman Delanty, Evan E. Eichler, David B. Goldstein, Yujun Han, Erin L. Heinzen, Michael R. Johnson, Anthony G. Marson, Heather C. Mefford, Sahar Esmaeeli Nieh, Terence J. O’Brien, Stephen Petrou, Slavé Petrovski, Elizabeth K. Ruzzo

Publikováno v: The American journal of human genetics
Møller, R S, EuroEPINOMICS RES Consortium, Epilepsy Phenome/Genome Project & Epi4K Consortium 2014, ' De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies ', American Journal of Human Genetics, vol. 95, no. 4, pp. 360-370 . https://doi.org/10.1016/j.ajhg.2014.08.013

Emerging evidence indicates that epileptic encephalopathies are genetically highly heterogeneous, underscoring the need for large cohorts of well-characterized individuals to further define the genetic landscape. Through a collaboration between two c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5621084f9d64cf23e269c01040b9b090
https://pubmed.ncbi.nlm.nih.gov/25262651

Guidelines for the Evaluation and Management of Status Epilepticus

Autor: Michael R. Sperling, Rodney Bell, Brian K. Alldredge, Gretchen M. Brophy, David M. Treiman, Thomas P. Bleck, Lori Shutter, Jan Claassen, Tracy A. Glauser, Suzette M. LaRoche, James J. Riviello, Paul M. Vespa

Publikováno v: Acad Emerg Med

Status epilepticus (SE) treatment strategies vary substantially from one institution to another due to the lack of data to support one treatment over another. To provide guidance for the acute treatment of SE in critically ill patients, the Neurocrit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2340b89206a4dfaa76e313ff0988dfab
https://doi.org/10.1007/s12028-012-9695-z

Improving safety culture on adult medical units through multidisciplinary teamwork and communication interventions: the TOPS Project

Autor: Mary A. Blegen, Susan Gearhart, Andrew A. Auerbach, Niraj L. Sehgal, Brian K. Alldredge, Robert M. Wachter

Publikováno v: Quality and Safety in Health Care. 19:346-350

Aim The goal of this project was to improve unit-based safety culture through implementation of a multidisciplinary (pharmacy, nursing, medicine) teamwork and communication intervention. Method The Agency for Healthcare Research and Quality Hospital

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ff69f63f566bcd9007f29dee0acddf
https://doi.org/10.1136/qshc.2008.031252