Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Brian J. Sheahan"'
Autor:
Arcangelo Gentile, Giancarlo Avallone, Luisa Vera Muscatello, Cinzia Benazzi, Joana Gp. Jacinto, Brian J. Sheahan, Marilena Bolcato
Publikováno v:
Journal of Comparative Pathology. 184:84-94
Congenital tumours and tumour-like lesions represent a group of rare disorders in both veterinary and human medicine that arise from tissue remnants and are detected during pregnancy or within the first 2-3 months of life. Different forms of congenit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65e736b05afc662cdf8801f19ed18be
https://doi.org/10.1016/j.jcpa.2021.02.003
https://doi.org/10.1016/j.jcpa.2021.02.003
Autor:
Brian J. Sheahan, Gregory J. Atkins
Publikováno v:
Journal of General Virology. 97:1283-1296
Alphaviruses are enveloped viruses with a positive-stranded RNA genome, of the family Togaviridae. In mammals and birds they are mosquito-transmitted and are of veterinary and medical importance. They cause primarily two types of disease: encephaliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a657f0be6e87b328e72ed6ca3e8fd4d
https://doi.org/10.1099/jgv.0.000467
https://doi.org/10.1099/jgv.0.000467
Publikováno v:
Neuropathology and Applied Neurobiology. 36:648-660
F. P. Roche, B. J. Sheahan, S. M. O'Mara and G. J. Atkins (2010) Neuropathology and Applied Neurobiology36, 648–660 Semliki Forest virus-mediated gene therapy of the RG2 rat glioma Aims: Glioblastoma multiforme is the most common and most malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::054703271393107cc72f72d762242b9b
https://doi.org/10.1111/j.1365-2990.2010.01110.x
https://doi.org/10.1111/j.1365-2990.2010.01110.x
Autor:
Ken E. Olson, Amber J. Singh, Christopher H. Logue, Dennis J. Pierro, Christopher F. Bosio, Aaron T. Phillips, Catharine M. Bosio, Thomas Welte, Ann M. Powers, Kimberley M. Keene, Jeremy P. Ledermann, Aaron C. Brault, Nicole L. Marlenee, Brian J. Sheahan
Publikováno v:
Journal of General Virology. 90:1848-1858
Little is known about viral determinants of virulence associated with western equine encephalitis virus (WEEV). Here, we have analysed six North American WEEV isolates in an outbred CD1 mouse model. Full genome sequence analyses showed ≤2.7 % diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d04f12aebfa5f99acc3662382aee58
https://doi.org/10.1099/vir.0.008656-0
https://doi.org/10.1099/vir.0.008656-0
Publikováno v:
Journal of General Virology. 87:937-947
Major virulence determinants ofSemliki Forest virus(SFV) lie within the non-structural genes that form the replicase complex proteins. Gene exchange between virulent and avirulent viruses has shown that the nsP3 gene, which has essential 5′ conserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2cdd928b3c07a9c15dfb6ecb226b9c
https://doi.org/10.1099/vir.0.81406-0
https://doi.org/10.1099/vir.0.81406-0
Publikováno v:
Scopus-Elsevier
A 3-year-old Wirehaired Fox Terrier was presented to the University Veterinary Hospital, University College Dublin, for evaluation of chronic cough of 8-months duration. Bronchoscopy showed a severely dilated collapsed left principal bronchus filled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c56ce5d107ca173c0ddf08f0dadb22
https://doi.org/10.1111/j.1939-165x.2004.tb00369.x
https://doi.org/10.1111/j.1939-165x.2004.tb00369.x
Publikováno v:
Molecular Therapy. 8:886-894
We have initiated studies to determine the feasibility of employing the Semliki Forest virus (SFV) expression system as a central nervous system (CNS) vector. We investigated the effects of infecting Balb/c mice intranasally (i.n.) with recombinant S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a108cb4b3a17faf4d57f6e7d429eb9
https://doi.org/10.1016/j.ymthe.2003.09.010
https://doi.org/10.1016/j.ymthe.2003.09.010
Publikováno v:
Neuropathology and Applied Neurobiology. 29:553-562
Semliki Forest virus (SFV) infection of mice provides a useful model for the analysis of viral neuropathogenesis. In this study, the roles of interferon (IFN)-gamma and nitric oxide (NO) in the pathogenesis of SFV infection were assessed using mice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133e7d47f1613f24d7e9681b6e4a1a2f
https://doi.org/10.1046/j.1365-2990.2003.00492.x
https://doi.org/10.1046/j.1365-2990.2003.00492.x
Publikováno v:
Veterinary Immunology and Immunopathology. 94:185-190
Semliki Forest virus (SFV) infection of mice is a useful model of viral neuropathogenesis in animals and avirulent strains such as SFV-A7 induce immune-mediated demyelination and death of neurones by necrosis and apoptosis. Matrix metalloproteinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aa3ba8fd9a1d0b8183fc3f995787ca
https://doi.org/10.1016/s0165-2427(03)00082-5
https://doi.org/10.1016/s0165-2427(03)00082-5
Autor:
Hugh W Reid, Gregory J. Atkins, Margaret M Morris-Downes, Brian J. Sheahan, Peter Liljeström, Marina N. Fleeton
Publikováno v:
Vaccine. 19:3877-3884
This study has examined the efficacy following intramuscular administration of a recombinant Semliki Forest virus (rSFV) vaccine, encoding the prME and NS1 proteins of louping ill virus (LIV), in sheep. Administration of rSFV-LIV vaccine resulted in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349cfd88cd4fa817a2c8e9b8a4d066fa
https://doi.org/10.1016/s0264-410x(01)00126-8
https://doi.org/10.1016/s0264-410x(01)00126-8