Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brian J. Scaglione"'
Autor:
Elizabeth S. Raveche, Gerald Marti, Helen Fernandes, Alessia Baccarini, Brian D. Brown, Frederick D. Coffman, Brian J. Scaglione, Erica Salerno
Supplementary Data from Correcting miR-15a/16 genetic defect in New Zealand Black mouse model of CLL enhances drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a607ed038ecf9582943ab573a6110cbf
https://doi.org/10.1158/1535-7163.22484664.v1
https://doi.org/10.1158/1535-7163.22484664.v1
Autor:
Elizabeth S. Raveche, Gerald Marti, Helen Fernandes, Alessia Baccarini, Brian D. Brown, Frederick D. Coffman, Brian J. Scaglione, Erica Salerno
Alterations in the human 13q14 genomic region containing microRNAs mir-15a and mir-16-1 are present in most human chronic lymphocytic leukemia (CLL). We have previously found the development of CLL in the New Zealand Black murine model to be associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4eb7440a26131bd010c01dc11b00ac
https://doi.org/10.1158/1535-7163.c.6531519.v1
https://doi.org/10.1158/1535-7163.c.6531519.v1
Autor:
Maria Fernanda Laurindo, Erica Salerno, Sivasubramanian Baskar, Elizabeth Raveche, Fermina Mazzella, Alexander Jankovic, Yao Yuan, Christoph Rader, Gerald E. Marti, Brian J. Scaglione, Daryl Despres
Publikováno v:
Cytometry Part B: Clinical Cytometry. :S98-S109
Background: Similar to a subset of human patients who progress from monoclonal B lymphocytosis (MBL) to chronic lymphocytic leukemia (CLL), New Zealand Black (NZB) mice have an age-associated progression to CLL. The murine disease is linked to a gene
Autor:
Gerald E. Marti, Brian D. Brown, Erica Salerno, Frederick D. Coffman, Alessia Baccarini, Brian J. Scaglione, Helen Fernandes, Elizabeth Raveche
Publikováno v:
Molecular Cancer Therapeutics. 8:2684-2692
Alterations in the human 13q14 genomic region containing microRNAs mir-15a and mir-16-1 are present in most human chronic lymphocytic leukemia (CLL). We have previously found the development of CLL in the New Zealand Black murine model to be associat
Autor:
Steven R. Bauer, Brian J. Scaglione, Vincent K. Tsiagbe, Elizabeth Raveche, Kinisha Gala, Jerome A. Langer, Gerald E. Marti, Erica Salerno, Yu Li, Manjing Pan, Howard Mostowski
Publikováno v:
Journal of Autoimmunity. 32:14-23
Regulatory T cells (Tregs) play an important role in protection against autoimmune disease and are also known to be potent inhibitors of anti-tumor immune responses. The New Zealand Black (NZB) mouse is a murine model for both autoimmune diseases, si
Autor:
Gideon Schreiber, Manjing Pan, Brian J. Scaglione, Jerome A. Langer, Elizabeth Raveche, Eyal Kalie
Publikováno v:
Biochemistry. 47:12018-12027
Type I interferons (IFNs) are multifunctional cytokines that activate cellular responses by binding a common receptor consisting of two subunits, IFNAR-1 and IFNAR-2. Although the binding of IFNs to IFNAR-2 is well characterized, the binding to the l
Autor:
Elizabeth Raveche, Frederick D. Coffman, Erica Salerno, Fatima Abbasi, Pablo Landgraf, Brian J. Scaglione, Gerald E. Marti, Sergei V. Kotenko, Murugabaskar Balan
Publikováno v:
British Journal of Haematology. 139:645-657
Summary Mouse models are valuable tools in the study of human chronic lymphocytic leukaemia (CLL). The New Zealand Black (NZB) strain is a naturally occurring model of late-onset CLL characterized by B-cell hyperproliferation and autoimmunity early i
Autor:
Désirée Bonci, Brian D. Brown, Brian J. Scaglione, Erica Salerno, Yao Yuan, Elizabeth Raveche, Frederick D. Coffman
Publikováno v:
Cancer Research. 70:4045-4045
Alterations in the human 13q14 genomic region containing the microRNAS, mir-15a and mir-16-1 are present in a majority of human chronic lymphocytic leukemia (CLL). We have previously found the development of CLL in the New Zealand Black (NZB) murine