Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brian J. O'Grady"'
Autor:
Andrew Kjar, Mia R. Haschert, José C. Zepeda, A. Joey Simmons, Alexis Yates, Daniel Chavarria, Melanie Fernandez, Gabriella Robertson, Adam M. Abdulrahman, Hyosung Kim, Nicole T. Marguerite, Rachel K. Moen, Lauren E. Drake, Corinne W. Curry, Brian J. O’Grady, Vivian Gama, Ken S. Lau, Brad Grueter, Jonathan M. Brunger, Ethan S. Lippmann
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114874- (2024)
Summary: Human neural organoid models have become an important tool for studying neurobiology. However, improving the representativeness of neural cell populations in such organoids remains a major effort. In this work, we compared Matrigel, a commer
Externí odkaz:
https://doaj.org/article/bad739db9cd140a9bad2592c28d9945f
Autor:
Alejandra I. Romero-Morales, Brian J. O'Grady, Kylie M. Balotin, Leon M. Bellan, Ethan S. Lippmann, Vivian Gama
Publikováno v:
HardwareX, Vol 6, Iss , Pp - (2019)
Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), have become a powerful system to study early development events and to
Externí odkaz:
https://doaj.org/article/dbf7cd62060a44ae948d60843dc07166
Autor:
Corinne W. Curry, Sarah M. Sturgeon, Brian J. O’Grady, Alexis K. Yates, Andrew Kjar, Hayden A. Paige, Lucas S. Mowery, Ketaki A. Katdare, Riya V. Patel, Kate Mlouk, Madison R. Stiefbold, Sidney Vafaie-Partin, Atsuyuki Kawabata, Rachel M. McKee, Stephanie Moore- Lotridge, Adrienne Hawkes, Jiro Kusunose, Katherine N. Gibson-Corley, Jeffrey Schmeckpeper, Jonathan G. Schoenecker, Charles F. Caskey, Ethan S. Lippmann
Publikováno v:
bioRxiv
Critical limb ischemia (CLI) occurs when blood flow is restricted through the arteries, resulting in ulcers, necrosis, and chronic wounds in the downstream extremities. The development of collateral arterioles (i.e. arteriogenesis), either by remodel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1f97f898e573fafccb848fc3b1bff6
https://europepmc.org/articles/PMC10245920/
https://europepmc.org/articles/PMC10245920/
Autor:
Kristin P. O’Grady, Brian J. O’Grady, Ethan S. Lippmann, Isabella Richter, Allison M. Bosworth, Lynn Lee, Hyosung Kim
Publikováno v:
Cell Mol Bioeng
IntroductionVascular endothelial cells respond to a variety of biophysical cues such as shear stress and substrate stiffness. In peripheral vasculature, extracellular matrix (ECM) stiffening alters barrier function, leading to increased vascular perm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f0077abe5c3523446b2f7977721ce
https://doi.org/10.1007/s12195-021-00706-8
https://doi.org/10.1007/s12195-021-00706-8
Autor:
Brian J. O’Grady, Ethan S. Lippmann
Publikováno v:
Curr Tissue Microenviron Rep
PURPOSE OF REVIEW: Stem cells are exquisitely sensitive to biophysical and biochemical cues within the native microenvironment. This review focuses on emerging strategies to manipulate neural cell behavior using these influences in three-dimensional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f9e1fe4c1c7e43e308d6984847e331
https://doi.org/10.1007/s43152-020-00003-y
https://doi.org/10.1007/s43152-020-00003-y
Autor:
Michael D. Geuy, Everett R. Allchin, Colin M. Fricker, John P. Wikswo, Hyosung Kim, Scott A. Guelcher, Leon M. Bellan, Neelansh N. Bute, Kylie M. Balotin, Brian J. O’Grady, Ethan S. Lippmann, Taylor E. Scott, Gregory B. Lowen, Matthew L Fitzgerald, David C. Florian
Publikováno v:
Lab Chip
Fabrication of microfluidic devices by photolithography generally requires specialized training and access to a cleanroom. As an alternative, 3D printing enables cost-effective fabrication of microdevices with complex features that would be suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d59c525c2f1141302f9a70cdbd49185
https://europepmc.org/articles/PMC8717820/
https://europepmc.org/articles/PMC8717820/
Autor:
David C. Florian, Colin M. Fricker, John P. Wikswo, Scott A. Guelcher, Ethan S. Lippmann, Leon M. Bellan, Brian J. O’Grady, Taylor E. Scott, Hyosung Kim, Gregory B. Lowen, Kylie M. Balotin, Everett R. Allchin, Neelansh N. Bute, Michael D. Geuy
Fabrication of microfluidic devices by photolithography generally requires specialized training and access to a cleanroom. As an alternative, 3D printing enables cost-effective fabrication of microdevices with complex features that would be suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f2778db82a46422a3a3bc5fe881cdf
https://doi.org/10.1101/2021.08.02.454773
https://doi.org/10.1101/2021.08.02.454773
Autor:
Ramnarayan Ramachandran, Dungeng Peng, Jens Meiler, Brian J. O’Grady, Dongxue Yang, Aparna Shekar, Eric Gouaux, Jenny I. Aguilar, Greta Galli, Nicholas G. Campbell, Harald H. Sitte, Vikas Navratna, Aurelio Galli, James S. Sutcliffe, Heinrich J.G. Matthies, Amanda M. Duran, Thomas Stockner, Hassane S. Mchaourab, Kevin Erreger, Leon M. Bellan, Alexander N. Morley
Publikováno v:
Proceedings of the National Academy of Sciences. 116:3853-3862
The human dopamine (DA) transporter (hDAT) mediates clearance of DA. Genetic variants in hDAT have been associated with DA dysfunction, a complication associated with several brain disorders, including autism spectrum disorder (ASD). Here, we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::642ea249f0b9bb71e8dbee01bd090674
https://doi.org/10.1073/pnas.1816247116
https://doi.org/10.1073/pnas.1816247116
Autor:
Jason X. Wang, Shannon Faley, Brian J. O’Grady, Ethan S. Lippmann, Leon M. Bellan, Daniel A. Balikov
Publikováno v:
SLAS Technology. 23:592-598
The fabrication of engineered vascularized tissues and organs requiring sustained, controlled perfusion has been facilitated by the development of several pump systems. Currently, researchers in the field of tissue engineering require the use of pump
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7046cc3469c23563017d4ece61b5d291
https://doi.org/10.1177/2472630318775059
https://doi.org/10.1177/2472630318775059
Autor:
Kylie M. Balotin, P. Mason McClatchey, Ethan S. Lippmann, Leon M. Bellan, Mukesh Kumar Gupta, Robert M. Weinstein, Kara S. Poole, Brian J. O’Grady, Allison M. Bosworth
Publikováno v:
ACS Biomater Sci Eng
In vitro models of the human central nervous system (CNS), particularly those derived from induced pluripotent stem cells (iPSCs), are becoming increasingly recognized as useful complements to animal models for studying neurological diseases and deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c70b77733baf5ccda57a20a0768f0a
https://europepmc.org/articles/PMC7791574/
https://europepmc.org/articles/PMC7791574/