Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Brian J. Kilbey"'
Publikováno v:
Experimental Parasitology. 91:126-132
Tosh, K., Cheesman, S., Horrocks, P., and Kilbey, B. 1999. Plasmodium falciparum: Stage-related expression of topoisomerase I. Experimental Parasitology 91, 126–132. The expression and activity of topoisomerase I (PfTopoI) has been examined during
Publikováno v:
Molecular and Biochemical Parasitology. 92:39-46
The stage-specific relationship between promoter activity, transcript production, protein expression and enzyme activity has been investigated for the gene encoding Plasmodium falciparum topoisomerase II (PfTopoII). Nuclear run-on experiments have sh
Autor:
Brian J. Kilbey
Publikováno v:
Journal of Pharmacy and Pharmacology. 49:71-76
Autor:
Brian J. Kilbey
Publikováno v:
Genetical Research. 69:75-78
Autor:
Paul Horrocks, Brian J. Kilbey
Publikováno v:
Molecular and Biochemical Parasitology. 82:207-215
RNase protection assays and primer extension analysis have been used to locate a major transcription start site 960 bp upstream from the translational start of the PfPCNA coding sequence. A second, minor, site is situated a further 40 bp upstream. In
Autor:
Brian J. Kilbey, Kerrie Tosh
Publikováno v:
Gene. 163:151-154
Part of the topoisomerase I (TopoI)-encoding gene from Plasmodium falciparum (Pf) was isolated by PCR from cDNA using oligodeoxyribonucleotides modelled on the highly conserved regions of sequence from other species. The entire TopoI gene was obtaine
Publikováno v:
Nucleic Acids Research. 21:239-243
The gene encoding the malarial homologue of proliferating cell nuclear antigen, PCNA, has been identified and characterised. It is located on chromosome 13. The coding sequence of 825 nucleotides predicts a protein of 30,586 Da. There are no introns
Autor:
Brian J. Kilbey
Publikováno v:
Ciba Foundation Symposium-Mutation as a Cellular Process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a0ed15f12e35b746d8a7bc896458125
https://doi.org/10.1002/9780470719718.ch5
https://doi.org/10.1002/9780470719718.ch5
Autor:
Kelly Lee Hamilton, Victoria H. Brophy, Brian J. Kilbey, Carol Hopkins Sibley, Sandie Cheesman, Jason M. Wooden, Eleanor G. Hankins
Publikováno v:
Methods (San Diego, Calif.). 13(2)
Biochemical and genetic analyses are required to identify potential drug targets in apicomplexan parasites, but these studies have proved difficult in most parasite systems. We have developed methods based on expression of parasite proteins in the bu