Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brian J. Kempf"'
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (31), pp.10624-10637. ⟨10.1074/jbc.RA120.013906⟩
Journal of Biological Chemistry, 2020, 295 (31), pp.10624-10637. ⟨10.1074/jbc.RA120.013906⟩
J Biol Chem
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (31), pp.10624-10637. ⟨10.1074/jbc.RA120.013906⟩
Journal of Biological Chemistry, 2020, 295 (31), pp.10624-10637. ⟨10.1074/jbc.RA120.013906⟩
J Biol Chem
International audience; Picornaviral RNA-dependent RNA polymerases (RdRPs) have low replication fidelity that is essential for viral fitness and evolution. Their global fold consists of the classical "cupped right hand" structure with palm, fingers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3fad718547c0ef67fb1fe4dcfc91b0
https://hal-pasteur.archives-ouvertes.fr/pasteur-03216660
https://hal-pasteur.archives-ouvertes.fr/pasteur-03216660
Publikováno v:
J Virol
Picornaviruses have both asexual and sexual RNA replication mechanisms. Asexual RNA replication mechanisms involve one parental template whereas sexual RNA replication mechanisms involve two or more parental templates. Because sexual RNA replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb43b7c7e23f3ab98e678a931d3c555
https://doi.org/10.1101/2019.12.13.876292
https://doi.org/10.1101/2019.12.13.876292
Publikováno v:
Journal of virology. 93(14)
Template-dependent RNA replication mechanisms render picornaviruses susceptible to error catastrophe, an overwhelming accumulation of mutations incompatible with viability. Viral RNA recombination, in theory, provides a mechanism for viruses to count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923d0c2dd024cdd7a4bffd9b09bde3df
https://pubmed.ncbi.nlm.nih.gov/31068422
https://pubmed.ncbi.nlm.nih.gov/31068422
Autor:
Brian J. Kempf, David J. Barton
Publikováno v:
Virus Research
Poly(A) tails are functionally important features of all picornavirus RNA genomes. Some viruses have genomes with relatively short poly(A) tails (encephalomyocarditis virus) whereas others have genomes with longer poly(A) tails (polioviruses and rhin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc7ae697f758aa68576903638eb8584
https://doi.org/10.1016/j.virusres.2014.12.030
https://doi.org/10.1016/j.virusres.2014.12.030
RNA recombination is important in the formation of picornavirus species groups and the ongoing evolution of viruses within species groups. In this study, we examined the structure and function of poliovirus polymerase, 3D pol , as it relates to RNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b615ba695f03fbcb2dd8a268c63f10ac
https://europepmc.org/articles/PMC5021434/
https://europepmc.org/articles/PMC5021434/
Publikováno v:
Journal of Virology. 84:2843-2858
A 3′ poly(A) tail is a common feature of picornavirus RNA genomes and the RNA genomes of many other positive-strand RNA viruses. We examined the manner in which the homopolymeric poly(A) and poly(U) portions of poliovirus (PV) positive- and negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfeb7a482a09e62879ec2207ef403c39
https://doi.org/10.1128/jvi.02620-08
https://doi.org/10.1128/jvi.02620-08
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 74:224-232
La Crosse (LAC) virus (family Bunyaviridae, genus Orthobunyavirus) small (S) segment negative-sense RNA genome (vRNA), positive-sense full-length RNA complement (vcRNA), and subgenomic mRNA were assayed in infected cell cultures and female Aedes (Och
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6d35531fada9cd0068227643285bcb3
https://doi.org/10.4269/ajtmh.2006.74.224
https://doi.org/10.4269/ajtmh.2006.74.224
Publikováno v:
Journal of General Virology. 82:2919-2926
The genetic consequences of passing three different strains of La Crosse (LAC) virus orally and transovarially in Aedes triseriatus mosquitoes were examined. Two of the LAC strains (WT LAC and LAC ORI) had been passaged numerous times in cell culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f9178a7d4582824716ba53e57b7a16
https://doi.org/10.1099/0022-1317-82-12-2919
https://doi.org/10.1099/0022-1317-82-12-2919
Publikováno v:
Journal of virology. 87(10)
Picornaviruses have 3′ polyadenylated RNA genomes, but the mechanisms by which these genomes are polyadenylated during viral replication remain obscure. Based on prior studies, we proposed a model wherein the poliovirus RNA-dependent RNA polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1fc59d329ea3111dc005f849eda86b
https://pubmed.ncbi.nlm.nih.gov/23468507
https://pubmed.ncbi.nlm.nih.gov/23468507
Autor:
Rohit K. Jangra, Tetsuro Shimakami, Daisuke Yamane, Carolyn Spaniel, Brian J. Kempf, Stanley M. Lemon, David J. Barton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(3)
MicroRNAs (miRNAs) are small noncoding RNAs that regulate eukaryotic gene expression by binding to regions of imperfect complementarity in mRNAs, typically in the 3′ UTR, recruiting an Argonaute (Ago) protein complex that usually results in transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd780af624c9e5bce30f31c9fb87775
https://pubmed.ncbi.nlm.nih.gov/22215596
https://pubmed.ncbi.nlm.nih.gov/22215596