Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brian J. Jurgielewicz"'
Autor:
Kelly M. Scheulin, Brian J. Jurgielewicz, Samantha E. Spellicy, Elizabeth S. Waters, Emily W. Baker, Holly A. Kinder, Gregory A. Simchick, Sydney E. Sneed, Janet A. Grimes, Qun Zhao, Steven L. Stice, Franklin D. West
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are associated with particular functions will likely increase the potential to predic
Externí odkaz:
https://doaj.org/article/6680f945ead74649a55304ae1530c1db
Publikováno v:
Nanoscale Research Letters, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Extracellular vesicles (EVs) are nanosized lipid bilayer-bound vesicles that are naturally secreted from most cell types as a communication mechanism to deliver proteins, lipids, and genetic material. Despite the therapeutic potential of EVs
Externí odkaz:
https://doaj.org/article/7e4cfcea39a54d70adb9570b0ecf7e4e
Autor:
Sydney E. Sneed, Kelly M. Scheulin, Erin E. Kaiser, Madison M. Fagan, Brian J. Jurgielewicz, Elizabeth S. Waters, Samantha E. Spellicy, Kylee J. Duberstein, Simon R. Platt, Emily W. Baker, Steven L. Stice, Holly A. Kinder, Franklin D. West
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and physiology to humans. The pig is an attractive model due to similarities in brain size, organiz
Externí odkaz:
https://doaj.org/article/33722d55cfbf4dc5af73b07d776604a2
Autor:
Samantha E. Spellicy, Kelly M. Scheulin, Emily W. Baker, Brian J. Jurgielewicz, Holly A. Kinder, Elizabeth S. Waters, Janet A. Grimes, Steven L. Stice, Franklin D. West
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Histopathological analysis of cellular changes in the stroked brain provides critical information pertaining to inflammation, cell death, glial scarring, and other dynamic injury and recovery responses. However, commonly used manual approaches are hi
Externí odkaz:
https://doaj.org/article/96037dfd79ff4c51b8411fdfa55c43ed
Autor:
Sydney E Sneed, Gregory Simchick, Emily W Baker, Brian J. Jurgielewicz, Qun Zhao, Kelly M. Scheulin, Elizabeth S. Waters, Janet A. Grimes, Samantha E. Spellicy, Holly A. Kinder, Steven L. Stice, Franklin D. West
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are associated with particular functions will likely increase the potential to predict functio
Autor:
Jeongyoun Ahn, Steven L. Stice, Nicole A. Lazar, J C Poythress, Brian J. Jurgielewicz, Cheolwoo Park, Franklin D. West, Kelly M. Scheulin, Erin E. Kaiser
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 5, Pp 842-850 (2021)
Neural Regeneration Research
Neural Regeneration Research
Magnetic resonance imaging (MRI) is a clinically relevant, real-time imaging modality that is frequently utilized to assess stroke type and severity. However, specific MRI biomarkers that can be used to predict long-term functional recovery are still
Autor:
Brian J. Jurgielewicz, Michael Bowler, Erin E. Kaiser, Franklin D. West, Robin L. Webb, Steven L. Stice, Samantha E. Spellicy
Publikováno v:
Translational Stroke Research
Magnetic resonance imaging (MRI) is a clinically relevant non-invasive imaging tool commonly utilized to assess stroke progression in real time. This study investigated the utility of MRI as a predictive measure of clinical and functional outcomes wh
Publikováno v:
Journal of Cancer Immunology. 3
Autor:
Franklin D. West, Emily W Baker, Brian J. Jurgielewicz, Kelly M. Scheulin, Monika Saini, Sydney E Sneed, Elizabeth S. Waters, Gregory Simchick, Qun Zhao, Samantha E. Spellicy, Holly A. Kinder, Steven L. Stice
Publikováno v:
Stroke. 52
Despite the devastating global impact of ischemic stroke, there are few Food and Drug Administration (FDA) approved treatments, none of which are capable of regenerating or replacing infarcted brain tissue. Recently, our group demonstrated that induc
Autor:
Robin L. Webb, Samantha E. Spellicy, Erin E. Kaiser, Franklin D. West, Steven L. Stice, Michael Bowler, Brian J. Jurgielewicz
Publikováno v:
Stroke. 51
In this study, we sought to identify acute MRI parameters which are predictive of long-term functional outcomes as well as assess the effects of a neural stem cell extracellular vesicle (NSC EV) therapeutic in a large animal model of ischemic stroke.