Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Brian J. Day"'
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103168- (2024)
Glutathione (GSH) is a major endogenous antioxidant, and its depletion has been observed in several brain diseases including epilepsy. Previous studies in our laboratory have shown that dimercaprol (DMP) can elevate GSH via post-translational activat
Externí odkaz:
https://doaj.org/article/ac26334e40894cd09de51be283779407
Autor:
Taylor Crue, Grace Yihua Lee, Joyce Yao-chun Peng, Niccolette Schaunaman, Hina Agraval, Brian J. Day, Kris Genelyn Dimasuay, Diana Cervantes, Hamid Nouri, Taylor Nichols, Paige Hartsoe, Mari Numata, Irina Petrache, Hong Wei Chu
Publikováno v:
Innate Immunity, Vol 29 (2023)
Vaping is an increasing health threat in the US and worldwide. The damaging impact of vaping on the human distal lung has been highlighted by the recent epidemic of electronic cigarette or vaping use-associated lung injury (EVALI). The pathogenesis o
Externí odkaz:
https://doaj.org/article/32325d546c74465ca09779b17b12324e
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionDeployment related asthma-like symptoms including distal airway obstruction have been described in U.S. military personnel who served in Iraq and Afghanistan. The mechanisms responsible for the development of distal airway obstruction in
Externí odkaz:
https://doaj.org/article/93ca73984a8c40ada2c0b1d066b9ad05
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 275-284 (2019)
Persistent inhibition of acetylcholinesterase resulting from exposure to nerve agents such as soman, is associated with prolonged seizure activity known as status epilepticus (SE). Without medical countermeasures, exposure to soman and resultant SE l
Externí odkaz:
https://doaj.org/article/c9de8c7f1bce405a8b22200c81180b2d
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1252 (2022)
The innate immune response to infection results in inflammation and oxidative damage, creating a paradox where most anti-inflammatory and antioxidant therapies can further suppress an already inadequate immune response. We have previously reported th
Externí odkaz:
https://doaj.org/article/70b1227299a04dffa1e56086bd4fd3ab
Autor:
Jennifer N. Pearson, Shane Rowley, Li-Ping Liang, Andrew M. White, Brian J. Day, Manisha Patel
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 289-297 (2015)
Cognitive dysfunction is an important comorbidity of temporal lobe epilepsy (TLE). However, no targeted therapies are available and the mechanisms underlying cognitive impairment, specifically deficits in learning and memory associated with TLE remai
Externí odkaz:
https://doaj.org/article/8aa29d3d42d347fd8c98ce88ce74a2e9
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 1068-1076 (2012)
Epileptic seizures are a common feature associated with inherited mitochondrial diseases. This study investigated the role of mitochondrial oxidative stress in epilepsy resulting from mitochondrial dysfunction using cross-bred mutant mice lacking mit
Externí odkaz:
https://doaj.org/article/7d2eb6fa6aa840f8a7cf687f363a3d1c
Autor:
Zheng Huang, Yih-Chih Hsu, Li-Bo Li, Luo-Wei Wang, Xiao-Dong Song, Christine M. N. Yow, Xia Lei, Ali I. Musani, Rong-Cheng Luo, Brian J. Day
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 8, Iss 1, Pp 1530002-1-1530002-13 (2015)
Photodynamic therapy (PDT) of cancer is a two-step drug-device combination modality, which involves the topical or systemic administration of a photosensitizer followed by light illumination of cancer site. In the presence of oxygen molecules, the li
Externí odkaz:
https://doaj.org/article/504b04620f6f453a8a185c0f1d478d96
Publikováno v:
Chemical Research in Toxicology. 34:2408-2423
Approximately 3 million United States military personnel and contractors were deployed to Southwest Asia and Afghanistan over the past two decades. After returning to the United States, many developed persistent respiratory symptoms, including those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ea8794580823498ffb0c29e46b7155
https://doi.org/10.1021/acs.chemrestox.1c00090
https://doi.org/10.1021/acs.chemrestox.1c00090
Autor:
Harry A Smith, Elysia Min, Kent Riemondy, Max A. Seibold, Brian J. Day, Katrina W. Kopf, Reena Berman, Jie Huang, Gregory P. Downey, Cecile S. Rose, Hong Wei Chu
Publikováno v:
Toxicol Sci
Upon returning from deployment to Afghanistan, a substantial number of U.S. military personnel report deployment-related lung disease (DRLD) symptoms, including those consistent with an asthma-like airways disease. DRLD is thought to be caused by pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1756dbebe0541f1956f08b65412d4772
https://doi.org/10.1093/toxsci/kfab065
https://doi.org/10.1093/toxsci/kfab065