Zobrazeno 1 - 10
of 332
pro vyhledávání: '"Brian J. Czerniecki"'
Autor:
Brandon Mistretta, Sakuni Rankothgedera, Micah Castillo, Mitchell Rao, Kimberly Holloway, Anjana Bhardwaj, Maha El Noafal, Constance Albarracin, Randa El-Zein, Hengameh Rezaei, Xiaoping Su, Rehan Akbani, Xiaoshan M. Shao, Brian J. Czerniecki, Rachel Karchin, Isabelle Bedrosian, Preethi H. Gunaratne
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe present here a strategy to identify immunogenic neoantigen candidates from unique amino acid sequences at the junctions of fusion proteins which can serve as targets in the development of tumor vaccines for the treatment of breastcance
Externí odkaz:
https://doaj.org/article/4ec9e2ca15084d978b27a5af1c2c1793
Autor:
James Sun, Xiaojun Zhong, Junjie Ma, Weihong Sun, Hyo S. Han, Hatem H. Soliman, Loretta S. Loftus, Ricardo L. B. Costa, Avan J. Armaghani, Aixa E. Soyano‐Muller, Brian J. Czerniecki, M. Catherine Lee, John V. Kiluk, Nazanin Khakpour, Susan J. Hoover, Christine Laronga, Hung T. Khong
Publikováno v:
Cancer Medicine, Vol 10, Iss 21, Pp 7665-7672 (2021)
Abstract Background Combination CDK4/6 inhibitor and endocrine therapy has been shown to significantly improve progression‐free survival (PFS) in patients with hormone receptor (HR)‐positive, HER2‐negative metastatic breast cancer (mBC). The ai
Externí odkaz:
https://doaj.org/article/a7be7c72b7844f4fa797e6ef99b9269b
Autor:
Matthew N. Mills, Afrin Naz, Chetna Thawani, Chelsea Walker, Nicholas B. Figura, Sergiy Kushchayev, Daniel E. Oliver, Arnold B. Etame, Hsiang-Hsuan Michael Yu, Timothy J. Robinson, James K. C. Liu, Michael A. Vogelbaum, Peter A. Forsyth, Brian J. Czerniecki, Hatem H. Soliman, Hyo S. Han, Kamran A. Ahmed
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Little is known about the safety and efficacy of concurrent capecitabine and stereotactic radiotherapy in the setting of breast cancer brain metastases (BCBM). Methods Twenty-three patients with BCBM underwent 31 stereotactic sess
Externí odkaz:
https://doaj.org/article/433dd3e76f2d4b08babfea9bf2da801c
Autor:
Matthew N. Mills, Chelsea Walker, Chetna Thawani, Afrin Naz, Nicholas B. Figura, Sergiy Kushchayev, Arnold Etame, Hsiang-Hsuan Michael Yu, Timothy J. Robinson, James Liu, Michael A. Vogelbaum, Peter A. Forsyth, Brian J. Czerniecki, Hatem H. Soliman, Hyo S. Han, Kamran A. Ahmed
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Due to recent concerns about the toxicity of trastuzumab emtansine (T-DM1) with stereotactic radiation, we assessed our institutional outcomes treating HER2-positive breast cancer brain metastases (BCBM) with T-DM1 and stereotacti
Externí odkaz:
https://doaj.org/article/562f020bb63d4b6b8b13382bb13bdcdb
Autor:
Yael Artzy-Randrup, Tamir Epstein, Joel S. Brown, Ricardo L. B. Costa, Brian J. Czerniecki, Robert A. Gatenby
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Disseminated cancer cells (DCCs) are detected in the circulation and bone marrow of up to 40% of breast cancer (BC) patients with clinically localized disease. The formation of metastases is governed by eco-evolutionary interactions of DCCs
Externí odkaz:
https://doaj.org/article/f49023cafb534e68bae333b8a306dcc9
Autor:
Kamran A. Ahmed, Casey L. Liveringhouse, Matthew N. Mills, Nicholas B. Figura, G. Daniel Grass, Iman R. Washington, Eleanor E. Harris, Brian J. Czerniecki, Peter W. Blumencranz, Steven A. Eschrich, Jacob G. Scott, Roberto Diaz, Javier F. Torres-Roca
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 163-169 (2019)
Background: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recur
Externí odkaz:
https://doaj.org/article/71ccf9dd842a45c3b2f9769c510aa567
Autor:
Nadia Nocera Zachariah, Amrita Basu, Namrata Gautam, Ganesan Ramamoorthi, Krithika N. Kodumudi, Nagi B. Kumar, Loretta Loftus, Brian J. Czerniecki
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Breast cancer (BC) prevention remains the ultimate cost-effective method to reduce the global burden of invasive breast cancer (IBC). To date, surgery and chemoprevention remain the main risk-reducing modalities for those with hereditary cancer syndr
Externí odkaz:
https://doaj.org/article/ec880474820f49c39ed7097d18ed36b6
Autor:
Kamran A. Ahmed, MD, Youngchul Kim, PhD, John A. Arrington, MD, Sungjune Kim, MD, PhD, Michelle DeJesus, BS, Aixa E. Soyano, MD, Avan J. Armaghani, MD, Ricardo L.B. Costa, MD, Hung T. Khong, MD, Loretta S. Loftus, MD, Marilin Rosa, MD, Jimmy J. Caudell, MD, PhD, Roberto Diaz, MD, PhD, Timothy J. Robinson, MD, PhD, Arnold B. Etame, MD, PhD, Nam D. Tran, MD, PhD, Solmaz Sahebjam, MD, Hatem H. Soliman, MD, Brian J. Czerniecki, MD, PhD, Peter A. Forsyth, MD, H. Michael Yu, MD, Hyo S. Han, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 6, Pp 100798- (2021)
Purpose: We hypothesize treatment with nivolumab and stereotactic radiosurgery (SRS) will be feasible and well tolerated, and may improve intracranial tumor control rates compared with SRS alone. Methods and Materials: The study was designed as a pro
Externí odkaz:
https://doaj.org/article/d3a069d067ee48fd8facf6e4317a3b58
Autor:
Corey Gallen, Christopher W. Dukes, Amy Aldrich, Lauren Macaisa, Qianxing Mo, Christopher L. Cubitt, Shari Pilon-Thomas, Anna R. Giuliano, Brian J. Czerniecki, Ricardo L. B. Costa
Publikováno v:
Vaccines, Vol 10, Iss 11, p 1931 (2022)
We conducted a prospective study to evaluate immune responses to SARS-CoV-2 in oncology workers in which we collected blood and clinical data every 6 months. Spike-specific CD4+ T-cells and immunoglobulin G responses were measured using interferon-ga
Externí odkaz:
https://doaj.org/article/27670b1d4b5f4bdf92fba4684012f681
Autor:
Amrita Basu, Ganesan Ramamoorthi, Gabriella Albert, Corey Gallen, Amber Beyer, Colin Snyder, Gary Koski, Mary L. Disis, Brian J. Czerniecki, Krithika Kodumudi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells in the tumor which are critical for activation of anti-tumor response either directly by themselves or by stimulating cytotoxic T cell activity. However, presen
Externí odkaz:
https://doaj.org/article/b0b91eb05a9543e286852852ed9356e3