Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Brian J Nieman"'
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72039 (2013)
It is important to understand changes in cell distribution that occur as a part of disease progression. This is typically achieved using standard sectioning and immunostaining, however, many structures and cell distribution patterns are not readily a
Externí odkaz:
https://doaj.org/article/791c84804ff545ddaa4c51729f6357cc
Autor:
Jason P Lerch, Lisa eGazdzinski, Jurgen eGermann, John G Sled, R. Mark eHenkelman, Brian J Nieman
Publikováno v:
Frontiers in Neuroinformatics, Vol 6 (2012)
High resolution MRI of the mouse brain is gaining prominence in estimating changes in neuroanatomy over time to understand both normal developmental as well as disease processes and mechanisms. These types of experiments, where a change in time is to
Externí odkaz:
https://doaj.org/article/5ffbf06ee6e54c839c1fb17f6b8963c0
Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernández-Beltrán, Juan I. López-Carbonero, Pablo Bascuñana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñoz de Bustillo Alfaro, Maria J. Sánchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106437- (2024)
TDP-43 pathology is found in several neurodegenerative disorders, collectively referred to as “TDP-43 proteinopathies”. Aggregates of TDP-43 are present in the brains and spinal cords of >97% of amyotrophic lateral sclerosis (ALS), and in brains
Externí odkaz:
https://doaj.org/article/76599e797bbd49ac8a63e0a6d72160dc
Autor:
Zeinab Ali, Juan M. Godoy-Corchuelo, Aurea B. Martins-Bach, Irene Garcia-Toledo, Luis C. Fernández-Beltrán, Remya R. Nair, Shoshana Spring, Brian J. Nieman, Irene Jimenez-Coca, Rasneer S. Bains, Hamish Forrest, Jason P. Lerch, Karla L. Miller, Elizabeth M. C. Fisher, Thomas J. Cunningham, Silvia Corrochano
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/3f0a2c5de56a43eca3efee6113651e7a
Autor:
Harikrishna Rallapalli, N. Sumru Bayin, Hannah Goldman, Dragan Maric, Brian J. Nieman, Alan P. Koretsky, Alexandra L. Joyner, Daniel H. Turnbull
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120198- (2023)
Magnetic Resonance Imaging (MRI) resolution continues to improve, making it important to understand the cellular basis for different MRI contrast mechanisms. Manganese-enhanced MRI (MEMRI) produces layer-specific contrast throughout the brain enablin
Externí odkaz:
https://doaj.org/article/f5291e0394464c1ea3b1b8d620ae031f
Autor:
Darren J. Fernandes, Shoshana Spring, Anna R. Roy, Lily R. Qiu, Yohan Yee, Brian J. Nieman, Jason P. Lerch, Mark R. Palmert
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Maternal environmental exposures, such as high-fat diets, diabetes and obesity, can induce long-term effects in offspring. These effects include increased risk of neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD),
Externí odkaz:
https://doaj.org/article/d97b5868a8fe46028363b423214433bb
Autor:
Ellen van der Plas, T. Leigh Spencer Noakes, Darci T. Butcher, Rosanna Weksberg, Laura Galin-Corini, Elizabeth A. Wanstall, Patrick Te, Laura Hopf, Sharon Guger, Brenda J. Spiegler, Johann Hitzler, Russell J. Schachar, Shinya Ito, Brian J. Nieman
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102428- (2020)
Introduction: Cure rates for pediatric acute lymphoblastic leukemia (ALL) have reached an all-time high (>90%); however, neurocognitive difficulties continue to affect quality of life in at least a subset of survivors. There are relatively few quanti
Externí odkaz:
https://doaj.org/article/c35aaa3954814a38952ea53818eb85ba
Autor:
A. Elizabeth de Guzman, Mashal Ahmed, Stefanie Perrier, Christopher Hammill, Yu-Qing Li, C. Shun Wong, Brian J. Nieman
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 113:390-400
Cranial radiation therapy for the treatment of pediatric brain tumors results in changes to brain development that are detectable with magnetic resonance imaging. We have previously demonstrated similar structural changes in both humans and mice. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f4af6d788956362d6a014589309d05
https://doi.org/10.1016/j.ijrobp.2022.01.035
https://doi.org/10.1016/j.ijrobp.2022.01.035
Autor:
Rebekah Tillotson, Keqin Yan, Julie Ruston, Taylor de Young, Alex Córdova, Valérie Turcotte- Cardin, Yohan Yee, Christine Taylor, Shagana Visuvanathan, Christian Babbs, Evgueni A Ivakine, John G Sled, Brian J Nieman, David J Picketts, Monica J Justice
Publikováno v:
Human Molecular Genetics.
ATRX is a chromatin remodelling ATPase that is involved in transcriptional regulation, DNA damage repair and heterochromatin maintenance. It has been widely studied for its role in ALT-positive cancers, but its role in neurological function remains e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5deafe9293a06140aac6f5c50adfcedd
https://doi.org/10.1093/hmg/ddad075
https://doi.org/10.1093/hmg/ddad075
Autor:
Brian J. Nieman, Ellen van der Plas, Shinya Ito, Johann Hitzler, Russell J. Schachar, Brenda J. Spiegler, Sharon L. Guger, Rosanna Weksberg, Darci T. Butcher, Yu-Qing Zhou, Connor Nicholls, Amanda Forwell, Thomas S. Przybycien, T. Leigh Spencer Noakes
Additional figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a19d13a3ba5ab8cf42558c6a925f9b
https://doi.org/10.1158/1078-0432.22469361.v1
https://doi.org/10.1158/1078-0432.22469361.v1
