Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Brian J Liddicoat"'
Autor:
Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184732 (2017)
TNF is a pro-inflammatory cytokine produced by both lymphoid and non-lymphoid cells. As a consequence of the widespread expression of its receptors (TNFR1 and 2), TNF plays a role in many important biological processes. In the context of influenza A
Externí odkaz:
https://doaj.org/article/260e87aec1f54e8a977e6b7d40d0d4ff
Publikováno v:
Experimental Hematology. 90:1-11
Whilst DNA cytosine methylation is the oldest and most well-studied epigenetic modification, basking in its glory days, it may be soon overshadowed by the new kid on the block: RNA adenosine methylation. This juxtaposition is indeed superficial, and
Autor:
Tanya Svinkina, James A. Kennedy, Emma C. Fink, D. R. Mani, Benjamin L. Ebert, Dylan N. Adams, Steven A. Carr, Saurav D. Haldar, Michelle C. Chen, Andrew A Guirguis, Namrata D. Udeshi, Brian J. Liddicoat, Marie McConkey, Andrew T. Nguyen
Publikováno v:
Blood. 132:1535-1544
Thalidomide and its derivatives, lenalidomide and pomalidomide, are clinically effective treatments for multiple myeloma and myelodysplastic syndrome with del(5q). These molecules lack activity in murine models, limiting investigation of their therap
Autor:
Mikolaj Slabicki, Eric Kuhn, Quinlan L. Sievers, Namrata D. Udeshi, Jessica A. Gasser, Adam S. Sperling, Rob S. Sellar, Hasmik Keshishian, Michael Burgess, Elyse A. Olesinski, Benjamin L. Ebert, Steven A. Carr, Rohan Sharma, Anthony Letai, Peter Miller, Shruti Bhatt, Max Jan, Brian J. Liddicoat, Mariateresa Fulciniti, Emma C. Fink, Dylan N. Adams, Nikhil C. Munshi
Publikováno v:
Blood. 134(2)
Pharmacologic agents that modulate ubiquitin ligase activity to induce protein degradation are a major new class of therapeutic agents, active in a number of hematologic malignancies. However, we currently have a limited understanding of the determin
Publikováno v:
WIREs RNA. 7:157-172
The conversion of genomically encoded adenosine to inosine in dsRNA is termed as A‐to‐I RNA editing. This process is catalyzed by two of the three mammalian ADAR proteins (ADAR1 and ADAR2) both of which have essential functions for normal organis
Autor:
Brian J. Liddicoat, Nicolas H. Thomä, Mikolaj Slabicki, Tarjei S. Mikkelsen, Quinlan L. Sievers, Aline Renneville, Richard D. Bunker, Georg Petzold, Benjamin L. Ebert, Wassim Abdulrahman
Publikováno v:
Science
Thalidomide-targeted degradation Thalidomide and its analogs improve the survival of patients with multiple myeloma and other blood cancers. Previous work showed that the drugs bind to the E3 ubiquitin ligase Cereblon, which then targets for degradat
Autor:
Katherine A. Watson, Nicole L. La Gruta, Brian J. Liddicoat, Alice E. Denton, Hayley A McQuilten, David C. Jackson, Weisan Chen, Natasha G. Swan, Jasmine Li, Katherine Kedzierska, Peter C. Doherty, Kylie M. Quinn, Wan-Ting Kan, Lukasz Kedzierski, Lorena E. Brown, Patrick C. Reading, Stephen J. Turner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0184732 (2017)
PLoS ONE, Vol 12, Iss 9, p e0184732 (2017)
TNF is a pro-inflammatory cytokine produced by both lymphoid and non-lymphoid cells. As a consequence of the widespread expression of its receptors (TNFR1 and 2), TNF plays a role in many important biological processes. In the context of influenza A
Autor:
Jin Billy Li, Joshua White, Ankita Gupte, Qin Li, Brian J. Liddicoat, Carl R. Walkley, Lokman Pang, Scott Taylor, Alistair M. Chalk, Sandra Linder, Jacki E. Heraud-Farlow
Publikováno v:
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-18 (2017)
Genome Biology, Vol 18, Iss 1, Pp 1-18 (2017)
Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thousands of A-to-I editing events are defined in the mouse, yet the functional impact of most is unknown. Editing causing protein recodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4503e044f36ae4c7d6a03e1c2dec38
https://acuresearchbank.acu.edu.au/item/8635w/protein-recoding-by-adar1-mediated-rna-editing-is-not-essential-for-normal-development-and-homeostasis
https://acuresearchbank.acu.edu.au/item/8635w/protein-recoding-by-adar1-mediated-rna-editing-is-not-essential-for-normal-development-and-homeostasis
Autor:
Alistair M. Chalk, Brian J. Liddicoat, Jennifer L. Moody, Carl R. Walkley, Megan R. Russell, Meaghan Wall, Göran Karlsson, Sofie Singbrant, Stefan Karlsson
Publikováno v:
Haematologica; 99(4), pp 647-655 (2014)
The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesi
Publikováno v:
Genomics Data
Genomics Data, Vol 2, Iss C, Pp 189-191 (2014)
Genomics Data, Vol 2, Iss C, Pp 189-191 (2014)
The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesi