Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brian J Belmont"'
Inducible control of subcellular RNA localization using a synthetic protein-RNA aptamer interaction.
Autor:
Brian J Belmont, Jacquin C Niles
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46868 (2012)
Evidence is accumulating in support of the functional importance of subcellular RNA localization in diverse biological contexts. In different cell types, distinct RNA localization patterns are frequently observed, and the available data indicate that
Externí odkaz:
https://doaj.org/article/27acdf4305a34a809d7094c323c50b1b
Autor:
Steven H. Kleinstein, Dennis R. Burton, Francois Vigneault, Christopher Clouser, David Koppstein, Brian J. Belmont, Adrian W. Briggs, Manu Tamminen, Jason Vander Heiden, Devin Sok, Stephen J. Goldfless, George M. Church, Sonia Timberlake
Tumor-infiltrating lymphocytes (TILs) are critical to anti-cancer immune responses, but their diverse phenotypes and functions remain poorly understood and challenging to study. We therefore developed a single-cell barcoding technology for deep chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedda0e4beba09869917e279268fd927
Autor:
Ruth Salmon, Eric M. Chadwick, Bailey Donahue, Melissa Chin, G. Grant Welstead, Clay Patton, Blythe D. Sather, Stephen Michael Burleigh, Dean Y. Toy, Brian J. Belmont, David Jeffrey Huss, Alexandra Croft, Stephen J. Goldfless, Cameron S. Brandt
Publikováno v:
Cancer Immunology Research. 7:A027-A027
Background: Adoptive T-cell therapy with engineered T-cell receptors (eTCR) has demonstrated promising, yet modest clinical benefit to date. Key obstacles for this technology are 1) competition with the endogenous TCR for CD3 components that are requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c119b6b86fcccb5af7ff0ffe56dc0b
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a027
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a027
Autor:
Jeffrey W. Jacobs, Shannon O. Harris, W. Michael Flanagan, Joni W. Lam, Ute Hoch, Sean Ritchie, Raymond V. Fucini, Stig Hansen, Marc J. Evanchik, David E. Stockett, Brian J. Belmont, Jeffrey A. Silverman, Kristin M. Zimmerman, Hashash Ahmad, Pietro Taverna, Jennifer N. Hogan, Juli N. Teague, Jennifer P. Arbitrario, Anthony Howlett, Michael J. Romanowski
Publikováno v:
Cancer Chemotherapy and Pharmacology. 65:707-717
The Aurora family of serine/threonine kinases (Aurora-A, Aurora-B, and Aurora-C) plays a key role in cells orderly progression through mitosis. Elevated expression levels of Aurora kinases have been detected in a high percentage of melanoma, colon, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f55f64b155510603db6969a00c09da
https://doi.org/10.1007/s00280-009-1076-8
https://doi.org/10.1007/s00280-009-1076-8
Autor:
Adrian W. Briggs, Christopher Clouser, Francois Vigneault, Brian J. Belmont, Katherine L. Connor, Sonia Timberlake, Stephen J. Goldfless, David Koppstein
Publikováno v:
Cancer Research. 76:1442-1442
We present high resolution single cell profiling of tumor infiltrating lymphocytes (TILs) for immune research and cancer target discovery. TILs hold the key to understanding anti-cancer immune responses but remain challenging to study due to their va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::696b14866c70fae21980c8178000e9dd
https://doi.org/10.1158/1538-7445.am2016-1442
https://doi.org/10.1158/1538-7445.am2016-1442
Autor:
Jacquin C. Niles, Brian J. Belmont
Publikováno v:
PLoS ONE
PLoS
PLoS ONE, Vol 7, Iss 10, p e46868 (2012)
PLoS
PLoS ONE, Vol 7, Iss 10, p e46868 (2012)
Evidence is accumulating in support of the functional importance of subcellular RNA localization in diverse biological contexts. In different cell types, distinct RNA localization patterns are frequently observed, and the available data indicate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feffeaf8f421b7094295ca1f4134a173
http://europepmc.org/articles/PMC3466194
http://europepmc.org/articles/PMC3466194
Autor:
Brian J. Belmont, Jacquin C. Niles
Publikováno v:
Prof. Niles via Howard Silver
The importance and pervasiveness of naturally occurring regulation of RNA function in biology is increasingly being recognized. A common mechanism uses inducible protein−RNA interactions to shape diverse aspects of cellular RNA fate. Recapitulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076a933b2fc8e8146e779297f19aa8b6
http://hdl.handle.net/1721.1/69073
http://hdl.handle.net/1721.1/69073
Autor:
Adrian W. Briggs, Brian J. Belmont, Sonia Timberlake, Francois Vigneault, Teresa J. Broering, David Fabrizio, Stephen J. Goldfless
Publikováno v:
Cancer Research. 75:643-643
One of the major challenges in developing new therapies for pancreatic cancer is the lack of known specific and sensitive targets to the cancer cells. In this study, we present a powerful way to identify novel specific targets to pancreatic cancer by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0bc18a327d1618f1c25d296b944a68
https://doi.org/10.1158/1538-7445.am2015-643
https://doi.org/10.1158/1538-7445.am2015-643
Autor:
Jacquin C. Niles, Alexandra M. de Paz, Stephen J. Goldfless, Brian J. Belmont, Jessica F. Liu
Publikováno v:
Nucleic Acids Research
Sequence-specific RNA–protein interactions, though commonly used in biological systems to regulate translation, are challenging to selectively modulate. Here, we demonstrate the use of a chemically-inducible RNA–protein interaction to regulate eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24fb896e8a33f5d0b2159499b35e26c
http://europepmc.org/articles/PMC3351163
http://europepmc.org/articles/PMC3351163