Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brian J Alps"'
Autor:
Douglas E. McBean, Victoria Winters, Craig B. Oswald, J. Michael Armstrong, Brian J. Alps, Alasdair D. Wilson
Publikováno v:
British Journal of Pharmacology. 116:3093-3098
1. A new, modified rat two vessel occlusion model (with hypotension) was established and the neuroprotective efficacy of the novel agent lifarizine (RS-87476) was examined. 2. The two vessel occlusion model used in the study was a modification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3613b2436336e4e7ad0fe35e473739bf
https://doi.org/10.1111/j.1476-5381.1995.tb15110.x
https://doi.org/10.1111/j.1476-5381.1995.tb15110.x
Publikováno v:
British Journal of Pharmacology. 115:1439-1446
1. The objective of this study was to evaluate the broad neurocytoprotective potential of the novel sodium-calcium ion channel modulator, lifarizine (RS-87476), in two rodent 72 h survival models of forebrain ischaemia. 2. Under fluothane anaesthesia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb933875383f2ef9bc3811402d3cb11
https://doi.org/10.1111/j.1476-5381.1995.tb16635.x
https://doi.org/10.1111/j.1476-5381.1995.tb16635.x
Publikováno v:
British Journal of Pharmacology. 109:175-177
1. Unilateral ligation of the right common carotid artery in the anaesthetized gerbil for 3 h caused a 62.7% decrease in ipsilateral dopamine in the corpus striatum from 1.40 (+/- 0.13, n = 27) micrograms g-1 in the non-ischaemic hemisphere to 0.47 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e9a1430e9f5a2bdf6f566b0d8e1c60
https://doi.org/10.1111/j.1476-5381.1993.tb13549.x
https://doi.org/10.1111/j.1476-5381.1993.tb13549.x
Publikováno v:
British Journal of Pharmacology. 93:877-883
1. Morphological changes characterizing delayed neuronal death (DND) of selectively vulnerable CA1 pyramidal cells in the hippocampus of the Mongolian gerbil brain occurred 72 h after transient (5 min) bilateral occlusion of the common carotid arteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee84a67c9e683846c398ce67994bed
https://doi.org/10.1111/j.1476-5381.1988.tb11475.x
https://doi.org/10.1111/j.1476-5381.1988.tb11475.x
Publikováno v:
Progress in neuro-psychopharmacology. 4(6)
1. 1. The neuro- and cardiovascular effects of RS-51324 (DL-4(5)-(2,6dichlorophenyl)-2-methoxycarbonyl-amino-4,5 dihydroimidazole) have been explored in animals. 2. 2. Antidepressant activities of RS-51324 were demonstrated by reserpine antagonism an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562358e26cfda3812d341c9c636e3789
https://pubmed.ncbi.nlm.nih.gov/7220671
https://pubmed.ncbi.nlm.nih.gov/7220671
Autor:
Maxine C. Allely, Brian J. Alps
1. A pentobarbitone-anaesthetized canine model of myocardial conduction was developed to evaluate drug effects on intra-atrial (I-A), intra-ventricular (I-V) and atrioventricular (A-V) conduction parameters, both at rest and during electrical pacing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fd194d12383fc69ffae7db587437ea
https://europepmc.org/articles/PMC1853802/
https://europepmc.org/articles/PMC1853802/
Publikováno v:
Biochemical Society Transactions. 15:1057-1058
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af622df2b6fb5efb55f1d8d2d04c339
https://doi.org/10.1042/bst0151057
https://doi.org/10.1042/bst0151057
Autor:
William K. Hass, Brian J. Alps
Publikováno v:
Neurology. 37:809-809
In a rat 3-day survival model of 10-minute four-vessel occlusion, halothane anesthesia was used to attenuate the ictal blood pressure elevation of the cerebral ischemic response and thereby maintain an isoelectric EEG. Selectively vulnerable regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18461d295013eb04d3cf754312a3364
https://doi.org/10.1212/wnl.37.5.809
https://doi.org/10.1212/wnl.37.5.809
Publikováno v:
Biochemical Society Transactions. 13:384-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e11eb563a9ae689cac7d089609ac91a
https://doi.org/10.1042/bst0130384
https://doi.org/10.1042/bst0130384