Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brian J, Polizzi"'
Autor:
William H. Miller, Catherine C.K. Yuan, Kalindi Vaidya, Brian J. Polizzi, Dennis T. Takata, Rebecca Claire Greenwood, Dirk A. Heerding, Mark A. Seefeld, Scott B. Winram, Valerie Berry, Martha S. Head, Walter J. Burgess, Andrew P. Fosberry, Nicola G. Wallis, David J. Payne, Stephen Rittenhouse, William F. Huffman, Paul M. Keller, Kevin L. Salyers, Manley Peter J, Kenneth A. Newlander, Deborah Dee Jaworski, Courtney Slater-Radosti, Cheryl A. Janson, Walter E. DeWolf, Irene N. Uzinskas, John Brosky, Stewart C. Pearson, Xiayang Qiu, Emile Chen, Terrance D. Moore, Martin G. Smyth
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3118-3124
Bacterial enoyl-acyl carrier protein (ACP) reductase (FabI) catalyzes the final step in each elongation cycle of bacterial fatty acid biosynthesis and is an attractive target for the development of new antibacterial agents. High-throughput screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997a68e3d46cb5b0dd9196003827969e
https://doi.org/10.1128/aac.46.10.3118-3124.2002
https://doi.org/10.1128/aac.46.10.3118-3124.2002
Autor:
William F. Huffman, Paul M. Keller, Valerie Berry, Walter E. DeWolf, William H. Miller, Catherine C.K. Yuan, Mark A. Seefeld, Stephen Rittenhouse, Brian J. Polizzi, Stewart C. Pearson, Cheryl A. Janson, Dirk A. Heerding, Walter J. Burgess, Martha S. Head, Terrance D. Moore, Kenneth A. Newlander, Xiayang Qiu, Irene N. Uzinskas, David J. Payne
Publikováno v:
Journal of Medicinal Chemistry. 45:3246-3256
Bacterial enoyl-ACP reductase (FabI) catalyzes the final step in each cycle of bacterial fatty acid biosynthesis and is an attractive target for the development of new antibacterial agents. Our eff...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac5be10717eef2aed6ee5bf83df2f1ef
https://doi.org/10.1021/jm020050+
https://doi.org/10.1021/jm020050+
Autor:
Chi Y. So, Hedia Marrakchi, Richard J. Heath, Walter E. DeWolf, David J. Payne, Joshua West, Shannon L. Reed, David J. Holmes, Brian J. Polizzi, Nicola G. Wallis, Chad Quinn, Charles O. Rock
The enoyl-(acyl-carrier protein) (ACP) reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. An extensively characterized NADH-dependent reductase, FabI, is widely distributed in bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4eb160da7d0c761fb73ec5f504761d
https://europepmc.org/articles/PMC1223239/
https://europepmc.org/articles/PMC1223239/
Autor:
William H, Miller, Mark A, Seefeld, Kenneth A, Newlander, Irene N, Uzinskas, Walter J, Burgess, Dirk A, Heerding, Catherine C K, Yuan, Martha S, Head, David J, Payne, Stephen F, Rittenhouse, Terrance D, Moore, Stewart C, Pearson, Valerie, Berry, Walter E, DeWolf, Paul M, Keller, Brian J, Polizzi, Xiayang, Qiu, Cheryl A, Janson, William F, Huffman
Publikováno v:
Journal of medicinal chemistry. 45(15)
Bacterial enoyl-ACP reductase (FabI) catalyzes the final step in each cycle of bacterial fatty acid biosynthesis and is an attractive target for the development of new antibacterial agents. Our efforts to identify potent, selective FabI inhibitors be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88457e027bb10a51dc01df9d68bcf47b
https://pubmed.ncbi.nlm.nih.gov/12109908
https://pubmed.ncbi.nlm.nih.gov/12109908