Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Brian J, Curtis"'
Autor:
Woonkee S. Jo, Brian J. Curtis, Mohammad Rehan, Maria L. Adrover-Castellano, David H. Sherman, Alan R. Healy
Publikováno v:
JACS Au, Vol 4, Iss 5, Pp 2058-2066 (2024)
Externí odkaz:
https://doaj.org/article/6da09e24480f446fa84294b10d76cfbf
Autor:
Bennett W. Fox, Maximilian J. Helf, Russell N. Burkhardt, Alexander B. Artyukhin, Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder, Amaresh Chaturbedi, Arnaud Tauffenberger, Chester J. J. Wrobel, Ying K. Zhang, Siu Sylvia Lee, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression, b
Externí odkaz:
https://doaj.org/article/c560af47fb5e4536a8660e27f05de7c2
Autor:
Bennett W. Fox, Maximilian J. Helf, Russell N. Burkhardt, Alexander B. Artyukhin, Brian J. Curtis, Diana Fajardo Palomino, Allen F. Schroeder, Amaresh Chaturbedi, Arnaud Tauffenberger, Chester J. J. Wrobel, Ying K. Zhang, Siu Sylvia Lee, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4b532cc862454011b496301edad55304
Autor:
Russell N. Burkhardt, Alexander B. Artyukhin, Erin Z. Aprison, Brian J. Curtis, Bennett W. Fox, Andreas H. Ludewig, Diana Fajardo Palomino, Jintao Luo, Amaresh Chaturbedi, Oishika Panda, Chester J. J. Wrobel, Victor Baumann, Douglas S. Portman, Siu Sylvia Lee, Ilya Ruvinsky, Frank C. Schroeder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Biological sex affects all aspects of animal physiology. Using the model C. elegans, the authors show that metabolomes are highly sex-specific and include a vast space of yet unidentified metabolites that may control development and lifespan.
Externí odkaz:
https://doaj.org/article/ee59faf2849443c2ad2e5ad357aac4f5
Autor:
Brian J. Curtis, Tyler J. Schwertfeger, Russell N. Burkhardt, Bennett W. Fox, Jude Andrzejewski, Chester J. J. Wrobel, Jingfang Yu, Pedro R. Rodrigues, Arnaud Tauffenberger, Frank C. Schroeder
Publikováno v:
Journal of the American Chemical Society. 145:11611-11621
Autor:
Henry H Le, Chester JJ Wrobel, Sarah M Cohen, Jingfang Yu, Heenam Park, Maximilian J Helf, Brian J Curtis, Joseph C Kruempel, Pedro Reis Rodrigues, Patrick J Hu, Paul W Sternberg, Frank C Schroeder
Publikováno v:
eLife, Vol 9 (2020)
Signaling molecules derived from attachment of diverse metabolic building blocks to ascarosides play a central role in the life history of C. elegans and other nematodes; however, many aspects of their biogenesis remain unclear. Using comparative met
Externí odkaz:
https://doaj.org/article/ad5cace3227746cc9ccec0c24be6f529
Autor:
Jingfang Yu, Merly C. Vogt, Bennett W. Fox, Chester J. J. Wrobel, Diana Fajardo Palomino, Brian J. Curtis, Bingsen Zhang, Henry H. Le, Arnaud Tauffenberger, Oliver Hobert, Frank C. Schroeder
Publikováno v:
Nature Chemical Biology. 19:141-150
Autor:
Bennett W. Fox, Olga Ponomarova, Yong-Uk Lee, Gaotian Zhang, Gabrielle E. Giese, Melissa Walker, Nicole M. Roberto, Huimin Na, Pedro R. Rodrigues, Brian J. Curtis, Aiden R. Kolodziej, Timothy A. Crombie, Stefan Zdraljevic, L. Safak Yilmaz, Erik C. Andersen, Frank C. Schroeder, Albertha J. M. Walhout
Publikováno v:
Nature
Individuals can exhibit differences in metabolism caused by the interplay of genetic background, nutritional input, microbiota, and other environmental factors(1–4). It is difficult to connect differences in metabolism to genomic variation and deri
Publikováno v:
Health Psychology. 40:587-596
OBJECTIVE The adverse health effects of short sleep duration (i.e., six or fewer hours per night) are well established, including an increased risk of cardiovascular disease (CVD) and related mortality. However, there is heterogeneity in perceived sl
Autor:
Andreas H. Ludewig, Michael P. O'Donnell, Sarah M Cohen, Bennett W. Fox, Paul W. Sternberg, Pedro R Rodrigues, Brian J Curtis, Jingfang Yu, Chester J J Wrobel, Frank C. Schroeder
Publikováno v:
Journal of the American Chemical Society. 143:14676-14683
The recently discovered modular glucosides (MOGLs) form a large metabolite library derived from combinatorial assembly of moieties from amino acid, neurotransmitter, and lipid metabolism in the model organism C. elegans. Combining CRISPR-Cas9 genome