Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Brian I Lord"'
Publikováno v:
European Journal of Haematology. 41:278-284
The cycling rate of haemopoietic stem cells (day 9 CFU-S) and granulocyte-macrophage colony forming cells (GM-CFC) in mouse femora was, in response to reduced numbers, elevated at all times of sampling between 3 weeks and 10 months after 4 repeated d
Publikováno v:
Radiation Research. 156:488-494
The conjecture that germline mutations induced by radiation exposure before conception may predispose subsequent offspring to cancer remains contentious. Previous experimental studies have shown that preconception paternal irradiation with (239)Pu in
Publikováno v:
International Journal of Radiation Biology. 76:77-85
To investigate the hypothesis that the developmental phase at which an individual encounters radiation damage affects its long-term sensitivity to a subsequent tumourigenic insult.Either the pregnant C57B16 mouse was exposed to 137Cs gamma-rays at 4
Publikováno v:
Radiation Protection Dosimetry. 79:391-394
Neutron-induced autoradiographs of femoral bone shafts taken from mice injected with 40 kBq.kg -1 239 Pu, 241 Am or 233 U, 1, 28 or 224 days previously. were analysed morphometrically in order to present a comparison of the changing radionuclide dist
Autor:
T. Michael Dexter, P. DeTakats, Michael George Hunter, Helena M. Earl, Mark Dougal, Mark Clemons, L. Michael Wood, Audrey Griffiths, Anthony Howell, Nydia G Testa, Julie Kiernan, Ken Watanabe, Andrew Millar, KE Towlson, Jan Dürig, Ernest Marshall, Lloyd George Czaplewski, Brian I Lord, David Miles
Publikováno v:
Blood. 92:1532-1540
BB-10010 is a variant of the human form of macrophage inflammatory protein-1 (MIP-1), which has been shown in mice to block the entry of hematopoietic stem cells into S-phase and to increase their self-renewal capacity during recovery from cyto
Publikováno v:
Chinese Science Bulletin. 42:155-159
Publikováno v:
British Journal of Cancer
Macrophage inflammatory protein-1 alpha (MIP-1 alpha) is an inhibitor of stem cell proliferation affording protection against damage from agents that express their cytotoxicity specifically in the DNA synthesis phase of the cell cycle. Its ability al
Autor:
Lloyd George Czaplewski, LB Woolford, Matthew John Mccourt, Michael George Hunter, Brian I Lord, L. M. Wood, Richard Mark Edwards
Publikováno v:
Blood. 85:3412-3415
BB-10010 is a genetically engineered variant of human macrophage inflammatory protein-1 alpha with improved solution properties. We show here that it mobilizes stem cells into the peripheral blood. We investigated the mobilizing effects of BB-10010 o
Autor:
Lorna B Woolford, Brian I Lord
Publikováno v:
STEM CELLS. 11:212-217
The practicalities of gene transfer therapy using retroviral vector systems require both that host cells be as primitive as possible and that those cells be proliferating. Here, the kinetics of hemopoietic stem cells with marrow repopulating ability
Autor:
Eric G. Wright, Brian I Lord
Publikováno v:
Baillière's Clinical Haematology. 5:499-507