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pro vyhledávání: '"Brian Hugh Ridgway"'
Autor:
Matthew Sangyup Lee, Robin Tammie Noguchi, John M. Nuss, Peiwen Zu, Jeff Chen, Brian Kane, Naing Aay, Jia Li, Xian Shi, Brian Hugh Ridgway, Craig Stacy Takeuchi, Elena S. Koltun, Lisa E. Meyr, Henry Johnson, Timothy Patrick Forsyth, Sergey Epshteyn, Brown S David, Byung Gyu Kim, Stefan Engst, Adam A. Galan, Arlyn Arcalas, Gary L. Lewis, Jean-Francois Martini, Vicky Chan, Thomas J. Stout, Robert Kassees, Shwu-Hwa Lin, James W. Leahy, Wentao Zhang, Grace Mann, Philip Tong, Ron Aoyama, Patrick Kearney, Michael Pack, Peiwen Yu, Steven Brian Gendreau, Tai P. Huynh, John Woolfrey, Hongwang Du, Mohamed Abdulkader Ibrahim
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(24)
We report the discovery of a series of 4-aryl-2-aminoalkylpyrimidine derivatives as potent and selective JAK2 inhibitors. High throughput screening of our in-house compound library led to the identification of hit 1, from which optimization resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fee7a24cc4076c5e7fbdacc64bdc9f
https://pubmed.ncbi.nlm.nih.gov/23127890
https://pubmed.ncbi.nlm.nih.gov/23127890
