Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Brian Hsueh"'
Autor:
Eric M. Trautmann, Daniel J. O’Shea, Xulu Sun, James H. Marshel, Ailey Crow, Brian Hsueh, Sam Vesuna, Lucas Cofer, Gergő Bohner, Will Allen, Isaac Kauvar, Sean Quirin, Matthew MacDougall, Yuzhi Chen, Matthew P. Whitmire, Charu Ramakrishnan, Maneesh Sahani, Eyal Seidemann, Stephen I. Ryu, Karl Deisseroth, Krishna V. Shenoy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Surface two-photon imaging of the brain cannot access somatic calcium signals of neurons from deep layers of the macaque cortex. Here, the authors present an implant and imaging system for chronic motion-stabilized two-photon imaging of dendritic cal
Externí odkaz:
https://doaj.org/article/862821d7098a4f46ba50d01c4f46809e
Autor:
Maged Goubran, Christoph Leuze, Brian Hsueh, Markus Aswendt, Li Ye, Qiyuan Tian, Michelle Y. Cheng, Ailey Crow, Gary K. Steinberg, Jennifer A. McNab, Karl Deisseroth, Michael Zeineh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Many approaches exist to process data from individual imaging modalities, but integrating them is challenging. The authors develop an automated resource that enables co-registered network- and tract-level analysis of macroscopic in-vivo imaging and m
Externí odkaz:
https://doaj.org/article/f0971bd01cd840d797c0f0138c81f2fa
Autor:
Daniel J. O’Shea, Paul Kalanithi, Emily A. Ferenczi, Brian Hsueh, Chandramouli Chandrasekaran, Werapong Goo, Ilka Diester, Charu Ramakrishnan, Matthew T. Kaufman, Stephen I. Ryu, Kristen W. Yeom, Karl Deisseroth, Krishna V. Shenoy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-20 (2018)
Abstract Optogenetic tools have opened a rich experimental landscape for understanding neural function and disease. Here, we present the first validation of eight optogenetic constructs driven by recombinant adeno-associated virus (AAV) vectors and a
Externí odkaz:
https://doaj.org/article/06230dc486274d2584a529f403050899
Autor:
Brian Hsueh, Vanessa M. Burns, Philip Pauerstein, Katherine Holzem, Li Ye, Kristin Engberg, Ai-Chi Wang, Xueying Gu, Harini Chakravarthy, H. Efsun Arda, Gregory Charville, Hannes Vogel, Igor R. Efimov, Seung Kim, Karl Deisseroth
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods
Externí odkaz:
https://doaj.org/article/b005b26d2af84e9196f1657c71463209
Autor:
Brian Hsueh, Ritchie Chen, YoungJu Jo, Daniel Tang, Misha Raffiee, Yoon Seok Kim, Masatoshi Inoue, Sawyer Randles, Charu Ramakrishnan, Sneha Patel, Doo Kyung Kim, Tony X. Liu, Soo Hyun Kim, Longzhi Tan, Leili Mortazavi, Arjay Cordero, Jenny Shi, Mingming Zhao, Theodore T. Ho, Ailey Crow, Ai-Chi Wang Yoo, Cephra Raja, Kathryn Evans, Daniel Bernstein, Michael Zeineh, Maged Goubran, Karl Deisseroth
Publikováno v:
Nature, vol 615, iss 7951
Emotional states influence bodily physiology, as exemplified in the top-down process by which anxiety causes faster beating of the heart1–3. However, whether an increased heart rate might itself induce anxiety or fear responses is unclear3–8. Phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd16dc7e7e719aa2c5003927ea91cf41
https://escholarship.org/uc/item/2h52s061
https://escholarship.org/uc/item/2h52s061
Autor:
Joshua Franklin, Christopher M. Waters, Yann S. Dufour, Nicolas L. Fernandez, Nguyen Thi Quynh Nhu, Brian Hsueh
Publikováno v:
Proceedings of the National Academy of Sciences. 117:29046-29054
The cell morphology of rod-shaped bacteria is determined by the rigid net of peptidoglycan forming the cell wall. While V. cholerae grows into a curved shape under most conditions, straight rods have been observed. However, the signals and regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1e26b6ccbb60c4b0b4fa91f4779577
https://doi.org/10.1073/pnas.2010199117
https://doi.org/10.1073/pnas.2010199117
Autor:
Quynh-Anh Nguyen, Misha Raffiee, Ritchie Chen, Soo Hyun Kim, Charu Ramakrishnan, Brian Hsueh, Felicity Gore, Sneha Patel, Ivan Soltesz, Yoon Seok Kim, Karl Deisseroth, Esther Krook-Magnusson
Publikováno v:
Nature Biotechnology. 39:161-164
Achieving temporally precise, noninvasive control over specific neural cell types in the deep brain would advance the study of nervous system function. Here we use the potent channelrhodopsin ChRmine to achieve transcranial photoactivation of defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23c2e0f7ff7ac1058e27401c37412eb
https://doi.org/10.1038/s41587-020-0679-9
https://doi.org/10.1038/s41587-020-0679-9
Publikováno v:
J Bacteriol
Listeria monocytogenes produces both c-di-AMP and c-di-GMP to mediate many important cellular processes, but the levels of both nucleotides must be regulated. c-di-AMP accumulation attenuates virulence and diminishes stress response, and c-di-GMP acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7756fe938cdfd8c3b415d5dc3e2b93ae
https://europepmc.org/articles/PMC8765449/
https://europepmc.org/articles/PMC8765449/
Autor:
Markus Aswendt, Maged Goubran, Michael Zeineh, Christoph Leuze, Karl Deisseroth, Gary K. Steinberg, Li Ye, Brian Hsueh, Qiyuan Tian, Jennifer A. McNab, Michelle Y. Cheng, Ailey K. Crow
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
3D histology, slice-based connectivity atlases, and diffusion MRI are common techniques to map brain wiring. While there are many modality-specific tools to process these data, there is a lack of integration across modalities. We develop an automated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6546e9a92eef626947fc260103c413bf
http://link.springer.com/article/10.1038/s41467-019-13374-0
http://link.springer.com/article/10.1038/s41467-019-13374-0
Autor:
Lucas Cofer, Matthew P. Whitmire, Brian Hsueh, Matthew MacDougall, Krishna V. Shenoy, William E. Allen, Yuzhi Chen, Charu Ramakrishnan, Gergő Bohner, Stephen I. Ryu, Eyal Seidemann, Sean Quirin, Maneesh Sahani, James H. Marshel, Isaac Kauvar, Sam Vesuna, Karl Deisseroth, Daniel J. O’Shea, Ailey K. Crow, Eric M. Trautmann, Xulu Sun
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Calcium imaging is a powerful tool for recording from large populations of neurons in vivo. Imaging in rhesus macaque motor cortex can enable the discovery of fundamental principles of motor cortical function and can inform the design of next generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081866091d7a6378023ee1d410127b0a
https://doi.org/10.1038/s41467-021-23884-5
https://doi.org/10.1038/s41467-021-23884-5