Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brian Hicke"'
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Autor:
Larry Rea, Barry N. Kreiswirth, Robert D. Jenison, Evelyn Woodruff, Wanyuan Ao, Brian Hicke, Stephen Aldous
Publikováno v:
Journal of Clinical Microbiology. 50:2433-2440
Multidrug-resistant Mycobacterium tuberculosis strains are widespread and present a challenge to effective treatment of this infection. The need for a low-cost and rapid detection method for clinically relevant mutations in Mycobacterium tuberculosis
Autor:
John S. Dunn, Diane Weed, Christopher Pasko, Evelyn Woodruff, Robert D. Jenison, Xiaotian Zheng, Brian Hicke, Dan Nieuwlandt, Heidi Jaeckel
Publikováno v:
Journal of Clinical Microbiology. 50:810-817
Rapid diagnosis of staphylococcal bacteremia directs appropriate antimicrobial therapy, leading to improved patient outcome. We describe herein a rapid test (Staphylococcus to the species level as well as the presence or absence of the methicillin re
Autor:
Y F Chang, I Albinana, M C Willis, Brian Hicke, S Ringquist, L Moon-McDermott, C K Lynott, Tim Fitzwater, Susan Jennings, H L Han, David Parma, Andrea Koenig, Ajit Varki, R F Bargatze, S R Watson, Nissi Varki
Publikováno v:
Journal of Clinical Investigation. 98:2688-2692
Selectins participate in the initial events leading to leukocyte extravasation from the blood into tissues. Thus the selectins have generated much interest as targets for antiinflammatory agents. Therapeutic molecules based on the monomeric carbohydr
Autor:
Benjamin Groves, Georges C Frech, Charles Owen, Edward Ager, Christopher Pasko, Larry Rea, Maylene Corpuz, Brian Hicke, Nathan A. Ledeboer, Gerald A. Denys, Wendy Smith, Wes Lindsey, Robert D. Jenison, Ashley Warcup, Denton Munns
Clostridium difficile can carry a genetically variable pathogenicity locus (PaLoc), which encodes clostridial toxins A and B. In hospitals and in the community at large, this organism is increasingly identified as a pathogen. To develop a diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96173438acf6d2ec6e048177a168e309
https://europepmc.org/articles/PMC3421499/
https://europepmc.org/articles/PMC3421499/
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 430 (2012)
BMC Research Notes
BMC Research Notes
Background The bacterium Staphylococcus aureus constitutes one of the most important causes of nosocomial infections. One out of every three individuals naturally carries S. aureus in their anterior nares, and nasal carriage is associated with a sign
Autor:
John C. Rohloff, Susan Jennings, Stephan Kraemer, Edward N. Brody, Mike Mehan, Evaldas Katilius, Jeffrey J. Walker, Ashley Bock, Shashi Kumar Gupta, Robert Mehler, Jeffrey D. Carter, Sally K. Nelson, Michele Nelson, Cate Fowler, Mike Watrobka, Bruce E. Eaton, Nebojsa Janjic, Thale C. Jarvis, Daniel Schneider, Suzanne Stratford, Ngan Le, Dennis Halladay, Deborah Ayers, Bridget Lollo, Sheri K. Wilcox, Glenn Sanders, Christopher Bock, Daniel I. Resnicow, Allison Weiss, Trudi Foreman, Sheela Waugh, Virginia Cunningham, Matt Otis, Tim Fitzwater, Martin Stanton, Tracy R. Keeney, Joe Heilig, Tad H. Koch, Gregory M. Husar, Larry Gold, Alex Stewart, Urs A. Ochsner, Nancy Kim, Britta Singer, Jennifer Bertino, Wes Mayfield, Daniel M. Levine, Mike Vrkljan, Meredith Goss, Malti Nikrad, Ashley Forbes, Jonathan D. Vaught, Thomas S. Parker, Luke Kroiss, Sarah Sattin, Dom Zichi, Alana Sterkel, Wes Lindsey, Alexey D. Wolfson, Steve Pietrasiewicz, Steve Wolk, Andrew B. Dalby, Brian Hicke, Rachel Ostroff, Jim Heil, Dylan Flather, Terese Kaske, Dan Nieuwlandt, Bharat Gawande, Chi Zhang, Magda Gunn
Publikováno v:
Nature Precedings
Interrogation of the human proteome in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology. We present a new aptamer-based proteomic technology for biomarker discovery capable of simultaneously measuring thousa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edba1f85bc2044e505d070fd97874ae7
http://hdl.handle.net/10101/npre.2010.4538.1
http://hdl.handle.net/10101/npre.2010.4538.1
Autor:
Glenn Foulds, Daniel J. Schneider, Brian Collins, Michele Nelson Hurst, Helen H. Petach, Larry Gold, Sheri K. Wilcox, Jim Heil, Sheela Waugh, Brian Hicke, Allison Weiss, Joseph S Heilig, Jody Davis, Chad Greef, Dominic Zichi, Michael Patrick Coleman, Barry Vant-Hull, Chris Bock, Gregory M. Husar, Rachel Ostroff, Darcey Miller
Publikováno v:
Proteomics. 4(3)
Multiplexed photoaptamer-based arrays that allow for the simultaneous measurement of multiple proteins of interest in serum samples are described. Since photoaptamers covalently bind to their target analytes before fluorescent signal detection, the a
The targeting of molecular repertoires to complex systems rather than biochemically pure entities is an accessible approach that can identify proteins of biological interest. We have probed antigens presented by a monolayer of tumor cells for their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a8a8ad5b39c8bf9676c356401a6212
https://europepmc.org/articles/PMC307582/
https://europepmc.org/articles/PMC307582/
Autor:
Yun Lin, Haolun Jin, James Tario, Hyung-Jung Pyun, Louis S. Green, Judy Ruckman, Brian Hicke, Choung U. Kim, Maria Fardis
Publikováno v:
Bioorganicmedicinal chemistry. 11(23)
A series of fumagillin analogues targeted at understanding tolerability of MetAP2 toward substitution at C4 and C6 were synthesized. Initially, the C6 side chain was maintained as cinnamoyl ester and C4 was modified. It was concluded that replacing t