Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Brian Haines"'
Autor:
Antoine Simoneau, Hsin-Jung Wu, Madhavi Bandi, Katherine Lazarides, Sining Sun, Shangtao Liu, Samuel Meier, Ashley Choi, Hongxiang Zhang, Binzhang Shen, Douglas Whittington, Sirimas Sudsakorn, Wenhai Zhang, Yi Yu, Yong Liu, Colin Liang, Michael Palmieri, Yingnan Chen, Brian Haines, Alice Tsai, Minjie Zhang, Alan Huang, Jannik Andersen, Tianshu Feng, Scott Throner, John Maxwell
Publikováno v:
Cancer Research. 83:4968-4968
TNG348 is a selective and potent inhibitor of the deubiquitinating enzyme USP1 specifically designed to target BRCA1/2mut vulnerabilities in breast and ovarian tumors. Here we present the biochemical, mechanistic, and in vitro and in vivo characteriz
Autor:
Kimberly J. Briggs, Alice Tsai, Minjie Zhang, Matthew R. Tonini, Brian Haines, Alan Huang, Kevin M. Cottrell
Publikováno v:
Cancer Research. 83:4970-4970
MTAP deletions occur in 10-15% of all human cancers, which provides one of the largest precision oncology patient populations. MTA-cooperative PRMT5 inhibitors leverage the well-characterized synthetic lethal relationship between PRMT5 inhibition and
Autor:
Randall B. Randolph, Christopher E. Hamilton, V. Yu. Glebov, Mark Gunderson, Tana Cardenas, J. M. Smidt, Brian M. Patterson, R. E. Olson, Brian Haines, John A. Oertel, Chad Forrest, R. C. Shah, Yong Ho Kim, Derek Schmidt, Minseong Lee, M.R. Douglas, Thomas J. Murphy, Brian Albright, Kevin Henderson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
The injection and mixing of contaminant mass into the fuel in inertial confinement fusion (ICF) implosions is a primary factor preventing ignition. ICF experiments have recently achieved an alpha-heating regime, in which fusion self-heating is the do
Autor:
Brian Albright, Todd Ditmire, Evan Dodd, Juan Fernandez, Donald Gautier, Brian Haines, Chengkun Huang, John Kline, Ari Le, Scott Luedtke, Markus Roth, Sasikumar Palaniyappan, Alexander Seaton, Lin Yin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3597a8fdb3a478f18846aac3f036c8d1
https://doi.org/10.2172/1843149
https://doi.org/10.2172/1843149
Autor:
Eric Loomis, Michael Grosskopf, Wayne Scales, Nomita Vazirani, Paul A. Bradley, Brian Haines, Scott L. England, D. J. Stark
Publikováno v:
2021 IEEE International Conference on Plasma Science (ICOPS).
Advances in machine learning have the ability to cut down design costs and enhance the design process for high-energy-density experiments. Machine learning can use expensive simulation data to search the design space efficiently for an optimal design
Autor:
Irina Sagert, Lindsey Kuettner, T. E. Quintana, T. Morrow, Brian Haines, D. S. Montgomery, Brian M. Patterson, D. J. Stark, Lynne Goodwin, J. P. Sauppe, Steven H. Batha, Paul Keiter, Sasikumar Palaniyappan, Eric Loomis, R. F. Sacks
Publikováno v:
2021 IEEE International Conference on Plasma Science (ICOPS).
Double shell capsules are an attractive alternative in inertial confinement fusion experiments due to their potential for achieving a low-convergence, robust burn 1 . However, symmetry degradation and accompanying reduced fuel confinement plagues the
Autor:
Ryan Sacks, Eric Loomis, Paul Keiter, Elizabeth Merritt, David Montgomery, Joshua Sauppe, Brian Haines, David Stark, Irina Sagert, Harry Robey, III, Sasikumar Palaniyappan, Tana Morrow, Sean Finnegan, John Kline, Steven Batha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd187c3f7686dfe8ca220b9554dc574
https://doi.org/10.2172/1804324
https://doi.org/10.2172/1804324
Publikováno v:
Journal of Facility Management Education and Research. 3:18-26
The purpose of this paper is to discover the current methods that facility managers use to manage and track assets and identify a set of attributes for Building Information Modelling (BIM) that can improve the efficiency of the current facility manag
Autor:
James Cooley, R. C. Shah, Randall B. Randolph, Meng-Chang Lee, Thomas E. Murphy, John A. Oertel, Nicolas Denissen, Jeffrey R. Haack, Thomas Day, Christopher E. Hamilton, Robert Gore, Yongho Kim, J. M. Smidt, Carlos Di Stefano, Lin Yin, R. T. Olson, Brian Haines, Brian Albright, Mark Gunderson, Tana Cardenas, Melissa Douglas
In inertial confinement fusion (ICF), deuterium-tritium (DT) fuel is brought to densities and temperatures where fusion ignition occurs. Mix of ablator material into the fuel may prevent ignition by diluting and cooling the fuel. MARBLE experiments a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62291b11cbd620976e192589485f3e5
https://doi.org/10.21203/rs.3.rs-135269/v1
https://doi.org/10.21203/rs.3.rs-135269/v1