Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Brian H, Youseff"'
Autor:
Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu, R. Travis Taylor
Publikováno v:
iScience, Vol 15, Iss , Pp 489-501 (2019)
Summary: Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein
Externí odkaz:
https://doaj.org/article/2689687ad01c41adb8ca44fe7f6df55a
Autor:
Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3269-3283.e6 (2019)
Summary: Tripartite motif-containing protein 5α (TRIM5α) is a cellular antiviral restriction factor that prevents early events in retrovirus replication. The activity of TRIM5α is thought to be limited to retroviruses as a result of highly specifi
Externí odkaz:
https://doaj.org/article/680b7a0b93c5469cbbde7dcdbb3d4d2d
Autor:
Adaeze O Izuogu, Kristin L McNally, Stephen E Harris, Brian H Youseff, John B Presloid, Christopher Burlak, Jason Munshi-South, Sonja M Best, R Travis Taylor
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1-30%. Despite severe disease in humans, TBFV infection of natural ro
Externí odkaz:
https://doaj.org/article/5bf74743187f459c9d747618a6488809
Autor:
Thomas G. Brewer, Kirk J. Lubick, Adaeze O. Izuogu, Saurabh Chattopadhyay, Saad Alqahtani, Kristin L. McNally, John B. Presloid, Sonja M. Best, Xiche Hu, Brian H. Youseff, R. Travis Taylor
Publikováno v:
iScience, Vol 15, Iss, Pp 489-501 (2019)
iScience
iScience
Summary Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48409536fe03ef4bac110c4cdd361fc1
http://www.sciencedirect.com/science/article/pii/S2589004219301476
http://www.sciencedirect.com/science/article/pii/S2589004219301476
Autor:
Brian H. Youseff, Carl V. Tyler
Publikováno v:
Evidence-Based Practice. 25:17-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf468ccfd4619550cd8a9a5f056c961
https://doi.org/10.1097/ebp.0000000000001620
https://doi.org/10.1097/ebp.0000000000001620
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002713 (2012)
In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system. The fungal pathogen Histoplasma capsulatum infects both neutrophils and m
Externí odkaz:
https://doaj.org/article/a1331ed247d14f0fabf9c77aebeedad0
Autor:
R. Travis Taylor, Kirk J. Lubick, Vanessa M. Hirsch, Jeremy Luban, Vanessa R. Montoya, Abhilash I. Chiramel, Fadila Bouamr, Omayra Méndez-Solís, Vinod Nair, Nicholas R. Meyerson, Sara L. Sawyer, Gail L. Sturdevant, Brian H. Youseff, Sonja M. Best, Kyusik Kim, Shelly J. Robertson, Kristin L. McNally, Robin M. Ireland, Catharine M. Bosio, Rebecca M. Broeckel
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3269-3283.e6 (2019)
Cell reports
Cell reports
SUMMARY Tripartite motif-containing protein 5α (TRIM5α) is a cellular antiviral restriction factor that prevents early events in retrovirus replication. The activity of TRIM5α is thought to be limited to retroviruses as a result of highly specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9ae36b08db33f516538c5f610770b9
https://doi.org/10.1101/605345
https://doi.org/10.1101/605345
Autor:
John B. Presloid, Jason Munshi-South, Christopher Burlak, R. Travis Taylor, Kristin L. McNally, Stephen E. Harris, Adaeze O. Izuogu, Sonja M. Best, Brian H. Youseff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1-30%. Despite severe disease in humans, TBFV infection of natural ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37abebd0ed068b53226e069583e2099b
https://pubmed.ncbi.nlm.nih.gov/28650973
https://pubmed.ncbi.nlm.nih.gov/28650973
Publikováno v:
Infection and Immunity. 81:2334-2346
Histoplasma capsulatum is a respiratory pathogen that infects phagocytic cells. The mechanisms allowing Histoplasma to overcome toxic reactive oxygen molecules produced by the innate immune system are an integral part of Histoplasma 's ability to sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312827785d1f9a044e730482a2e5f798
https://doi.org/10.1128/iai.00173-13
https://doi.org/10.1128/iai.00173-13
Publikováno v:
Journal of Proteome Research
The dimorphic fungal pathogen Histoplasma capsulatum causes respiratory and systemic disease. Within the mammalian host, pathogenic Histoplasma yeast infect, replicate within, and ultimately kill host phagocytes. Surprisingly, few factors have been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109e37b642776d9d8f96d7840eb19632
https://doi.org/10.1021/pr1011697
https://doi.org/10.1021/pr1011697