Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brian Glenn, St Hilaire"'
Autor:
Gordana Wutz, Rene Ladurner, Brian Glenn St Hilaire, Roman R Stocsits, Kota Nagasaka, Benoit Pignard, Adrian Sanborn, Wen Tang, Csilla Várnai, Miroslav P Ivanov, Stefan Schoenfelder, Petra van der Lelij, Xingfan Huang, Gerhard Dürnberger, Elisabeth Roitinger, Karl Mechtler, Iain Finley Davidson, Peter Fraser, Erez Lieberman-Aiden, Jan-Michael Peters
Publikováno v:
eLife, Vol 9 (2020)
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://doaj.org/article/50f9b518193c4de2ba8e04afd984547d
Autor:
Judy St. Leger, Bram van den Broek, Ahmed M.O. Elbatsh, Leonid L. Moroz, Evin Hildebrandt, Namita Mitra, Parwinder Kaur, Roger D. Kornberg, Federica Di Palma, Nils Stein, Weijie Yao, Theresa L.U. Burnham, Christopher J. Knight, Suhas S.P. Rao, Kazuhiro Maeshima, Asha S. Multani, Veronica F. Hinman, Aditya N. Mhaskar, José N. Onuchic, David Weisz, Sen Pathak, René H. Medema, Kevin A. Hovel, Arina D. Omer, Alexandria Mena, Andrea B. Kohn, Andrew J. Beel, Liesl Nel-Themaat, Benjamin D. Rowland, José Luis Gómez-Skarmeta, Bas van Steensel, Maria Cristina Gambetta, Claire Hoencamp, Christopher Lui, Roy G.H.P. van Heesbeen, Emma K. Farley, Olga Dudchenko, Michele Di Pierro, Neil D. Young, Meng C. Wang, Kerstin Lindblad-Toh, Pierre Jean Mattei, Tom van Schaik, Melanie Pham, Ruqayya Khan, Fabian Lim, Wesley C. Warren, Vinícius G. Contessoto, Richard R. Behringer, Hans H. Cheng, Alexander Haddad, Gregory A. Cary, Daniel Chauss, Zane Colaric, Hans Teunissen, Ayse Sena Mutlu, Zhenzhen Yang, Ángela Sedeño Cacciatore, Elzo de Wit, Sumitabha Brahmachari, Erez Lieberman Aiden, Karen Holcroft, Jonne A. Raaijmakers, Brian Glenn St Hilaire
Publikováno v:
Science
Science (New York, N.Y.), vol 372, iss 6545
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Science (New York, N.Y.), vol 372, iss 6545
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
We investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional(3D) genome architectures at the chromosome scale. Each type appears and disappears repeatedlyduring eukaryotic evolution. The type of genome arc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7def7f95c1bea4f8af665cc0bb48a7cb
Autor:
Saul Godinez Pulido, Suhas S.P. Rao, Andreas Gnirke, Zane Colaric, Joshua W. M. Theisen, Alyssa Blackburn, Erez Lieberman Aiden, Parwinder Kaur, David Weisz, Aviva Presser Aiden, Brian Glenn St Hilaire, Neva C. Durand, Namita Mitra, Ragini Mahajan, Olga Dudchenko
Early detection of infection with SARS-CoV-2 is key to managing the current global pandemic, as evidence shows the virus is most contagious on or before symptom onset. Here, we introduce a low-cost, high-throughput method for diagnosing and studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0426d1ef28bf944344525d23fc279a
https://doi.org/10.1101/2020.04.25.061499
https://doi.org/10.1101/2020.04.25.061499
Autor:
Brian Glenn St Hilaire
Here, we introduce a low-cost, high-throughput method for diagnosis of SARS-CoV-2 infection, dubbed Pathogen- Oriented Low-Cost Assembly & Re-Sequencing (POLAR), that enhances sensitivity by aiming to amplify the entire SARS-CoV-2 genome rather than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6e43fb63dca229327b4eed0b615144
https://doi.org/10.17504/protocols.io.bearjad6
https://doi.org/10.17504/protocols.io.bearjad6
Autor:
Stefan Schoenfelder, Brian Glenn St Hilaire, Petra van der Lelij, Jan-Michael Peters, Wen Tang, Gordana Wutz, Karl Mechtler, Iain F. Davidson, Adrian L. Sanborn, Benoit Pignard, Miroslav P Ivanov, Roman R. Stocsits, Peter Fraser, Elisabeth Roitinger, Xingfan Huang, Erez Lieberman Aiden, Kota Nagasaka, Rene Ladurner, Gerhard Dürnberger, Csilla Várnai
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c4e248dc34f280439bceca79883c99
Autor:
Adrian L. Sanborn, Elisabeth Roitinger, Gordana Wutz, Miroslav P Ivanov, Rene Ladurner, Petra van der Lelij, Xingfan Huang, Kota Nagasaka, Stefan Schoenfelder, Gerhard Dürnberger, Csilla Várnai, Iain F. Davidson, Roman R. Stocsits, Peter Fraser, Brian Glenn St Hilaire, Benoit Pignard, Karl Mechtler, Erez Lieberman-Aiden, Jan-Michael Peters, Wen Tang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c98df71591813ef0c13098de15676d
https://doi.org/10.7554/elife.52091.sa2
https://doi.org/10.7554/elife.52091.sa2
Autor:
Gordana, Wutz, Rene, Ladurner, Brian Glenn, St Hilaire, Roman R, Stocsits, Kota, Nagasaka, Benoit, Pignard, Adrian, Sanborn, Wen, Tang, Csilla, Várnai, Miroslav P, Ivanov, Stefan, Schoenfelder, Petra, van der Lelij, Xingfan, Huang, Gerhard, Dürnberger, Elisabeth, Roitinger, Karl, Mechtler, Iain Finley, Davidson, Peter, Fraser, Erez, Lieberman-Aiden, Jan-Michael, Peters
Publikováno v:
eLife
Eukaryotic genomes are folded into loops. It is thought that these are formed by cohesin complexes via extrusion, either until loop expansion is arrested by CTCF or until cohesin is removed from DNA by WAPL. Although WAPL limits cohesin’s chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dc5688f89331d4bc7276cb4c3262925
https://pubmed.ncbi.nlm.nih.gov/32065581
https://pubmed.ncbi.nlm.nih.gov/32065581
Autor:
Nathaniel T. Musial, Sanjit S. Batra, Erez Lieberman Aiden, Ragib Mostofa, Olga Dudchenko, Kelcie Pletch, Muhammad S. Shamim, Melanie Pham, Neva C. Durand, Marie Hoeger, Ben J. Novak, Sarah K. Nyquist, Weijie Yao, Arina D. Omer, Cynthia Pérez Estrada, Valeriya Korchina, Ania Tomaszewicz, Brian Glenn St Hilaire, Denise McAloose, Elena Stamenova, Joseph P. Flanagan
Hi-C contact maps are valuable for genome assembly (Lieberman-Aiden, van Berkum et al. 2009; Burton et al. 2013; Dudchenko et al. 2017). Recently, we developed Juicebox, a system for the visual exploration of Hi-C data (Durand, Robinson et al. 2016),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f3ff6fc25a64b9a09893e3e491f625
Autor:
Gavin D. Bascom, Jesse M. Engreitz, Douglass Turner, Elizabeth M. Perez, James T. Robinson, Tamar Schlick, Muhammad S. Shamim, Jaeweon Shin, Arina D. Omer, Rafael Casellas, Kyong-Rim Kieffer-Kwon, Erez Lieberman Aiden, Sarah E. Johnstone, Bradley E. Bernstein, Eric S. Lander, Xingfan Huang, Ziyi Ye, Adrian L. Sanborn, Ivan D. Bochkov, Brian Glenn St Hilaire, Su Chen Huang, Suhas S.P. Rao
Publikováno v:
PMC
The human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci—almost always bound by CTCF and cohesin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d47bd839bf5e77bc950748cd4e6e6f
http://hdl.handle.net/1721.1/118942
http://hdl.handle.net/1721.1/118942
Autor:
Rafael Casellas, Ivan D. Bochkov, Sarah E. Johnstone, Muhammad S. Shamim, Arina D. Omer, Elizabeth M. Perez, Suhas S.P. Rao, Xingfan Huang, Adrian L. Sanborn, Brian Glenn St Hilaire, Su Chen Huang, Erez Lieberman Aiden, Kyong-Rim Kieffer-Kwon, Eric S. Lander, Jesse M. Engreitz, Bradley E. Bernstein
SUMMARYThe human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci - almost always bound by CTCF and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcf57f3b60f747c2196dc264356e475
https://doi.org/10.1101/139782
https://doi.org/10.1101/139782