Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brian G. Topp"'
Publikováno v:
Journal of Diabetes Science and Technology. 3:68-82
Background: We used a mathematical model to estimate the contribution of urinary glucose excretion (UGE) to reported changes in body weight (BW) following oral antihyperglycemic agent (AHA) therapy. This modeling approach was used to gain novel insig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cdc28b9477f4ef7157ee81bf111be2
https://doi.org/10.1177/193229680900300108
https://doi.org/10.1177/193229680900300108
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 293:E1730-E1735
Both male Zucker Fatty (mZF) and lower-fat-fed female Zucker diabetic fatty (LF-fZDF) rats are obese but remain normoglycemic. Male ZDF (mZDF) and high-fat-fed female ZDF rats (HF-fZDF) are also obese but develop diabetes between 7 and 10 wk of age.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a06f278557e32efd2e2bfd4fb2edb4
https://doi.org/10.1152/ajpendo.00572.2007
https://doi.org/10.1152/ajpendo.00572.2007
Publikováno v:
Diabetologia. 47:1602-1610
Several studies have employed the chronic glucose infusion protocol to quantify the metabolic adaptations associated with a prolonged glucose challenge. However, the limited number of indices and time points reported by these studies has generated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ec9862cf49afcd244701373ac44ee6
https://doi.org/10.1007/s00125-004-1493-5
https://doi.org/10.1007/s00125-004-1493-5
Autor:
Brian G. Topp, Diane T. Finegood
Publikováno v:
Diabetes, Obesity and Metabolism. 3:20-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a7a8791de3442cb527ad6ac34422b2
https://doi.org/10.1046/j.1463-1326.2001.00030.x
https://doi.org/10.1046/j.1463-1326.2001.00030.x
Autor:
David Kojwang, Brian G. Topp, Marion J. Thomas, Thomas Leonard, M. Dawn McArthur, Robin E. Buckingham, Diane T. Finegood
Publikováno v:
Diabetes. 50:1021-1029
The evolution of diabetes in the male leptin receptor-deficient (fa/fa) Zucker diabetic fatty (ZDF) rat is associated with disruption of normal islet architecture, beta-cell degranulation, and increased beta-cell death. It is unknown whether these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44557ec26bcdc1b38a84a4373a335002
https://doi.org/10.2337/diabetes.50.5.1021
https://doi.org/10.2337/diabetes.50.5.1021
Autor:
Horatiu V. VinerianH.V. Vinerian, Laura L. AtkinsonL.L. Atkinson, Brian G. Topp, Narinder DhattN. Dhatt, Jenny AuJ. Au, Diane T. Finegood
Publikováno v:
Canadian journal of physiology and pharmacology. 87(8)
β-cell mass dynamics play an important role in the adaptation to obesity, as well as in the pathogenesis of type 2 diabetes. Here we used a 24-hour modified hyperglycemic clamp protocol to investigate the effect of increasing glucose concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af9549447dc80cf95c16a28f1aefc33
https://pubmed.ncbi.nlm.nih.gov/19767884
https://pubmed.ncbi.nlm.nih.gov/19767884
Autor:
Diane T., Finegood, Brian G., Topp
Publikováno v:
Diabetes, obesitymetabolism. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::541f2c521012adaa5ec0452246e3a2c0
https://pubmed.ncbi.nlm.nih.gov/11683855
https://pubmed.ncbi.nlm.nih.gov/11683855