Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Brian G. Rowan"'
Autor:
Katie M. Hamel, Trivia P. Frazier, Christopher Williams, Tamika Duplessis, Brian G. Rowan, Jeffrey M. Gimble, Cecilia G. Sanchez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2728 (2024)
Female breast cancer accounts for 15.2% of all new cancer cases in the United States, with a continuing increase in incidence despite efforts to discover new targeted therapies. With an approximate failure rate of 85% for therapies in the early phase
Externí odkaz:
https://doaj.org/article/60e48deb1f134cd2b67fdea5a43a681c
Autor:
Sen Liu, Bing Zhang, Brian G. Rowan, S. Michal Jazwinski, Asim B. Abdel-Mageed, Chad Steele, Alun R. Wang, Oliver Sartor, Tianhua Niu, Qiuyang Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Prostate cancer (PCa) is associated with advanced age, but how age contributes to prostate carcinogenesis remains unknown. The prostate-specific Pten conditional knockout mouse model closely imitates human PCa initiation and progression. To better un
Externí odkaz:
https://doaj.org/article/b11b9e0bbba44b3087d85c4021b548eb
Autor:
Van T. Hoang, Margarite D. Matossian, Deniz A. Ucar, Steven Elliott, Jacqueline La, Maryl K. Wright, Hope E. Burks, Aaron Perles, Fokhrul Hossain, Connor T. King, Valentino E. Browning, Jacob Bursavich, Fang Fang, Luis Del Valle, Akshita B. Bhatt, Jane E. Cavanaugh, Patrick T. Flaherty, Muralidharan Anbalagan, Brian G. Rowan, Melyssa R. Bratton, Kenneth P. Nephew, Lucio Miele, Bridgette M. Collins-Burow, Elizabeth C. Martin, Matthew E. Burow
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Conventional mitogen-activated protein kinase (MAPK) family members regulate diverse cellular processes involved in tumor initiation and progression, yet the role of ERK5 in cancer biology is not fully understood. Triple-negative breast cancer (TNBC)
Externí odkaz:
https://doaj.org/article/200b22265dbe421ba0329786d0153f68
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 26, Iss 1, Pp 37-41 (2014)
Our previous published data detected higher expression of total and active mitogen activated protein kinase (MAPK) in the epithelial vs. stromal cells of the endometrium. In the present work we compared the expression of ERK1/2 MAPK and estrogen rece
Externí odkaz:
https://doaj.org/article/00dea72466d5463bb69742f4cc510df4
Autor:
Adrienne K. Conger, Elizabeth C. Martin, Thomas J. Yan, Lyndsay V. Rhodes, Van T. Hoang, Jacqueline La, Muralidharan Anbalagan, Hope E. Burks, Brian G. Rowan, Kenneth P. Nephew, Bridgette M. Collins-Burow, Matthew E. Burow
Publikováno v:
Non-Coding RNA, Vol 2, Iss 3, p 8 (2016)
Estrogen receptor alpha (ERα) signaling pathways are frequently disrupted in breast cancer and contribute to disease progression. ERα signaling is multifaceted and many ERα regulators have been identified including transcription factors and growth
Externí odkaz:
https://doaj.org/article/d7c56c6cb5b74abaa121648b65023986
Autor:
Brian G. Rowan, David Hangauer, Yahao Bu, Latonya Carrier, Mei Sheng, Carolyn G. Marsden, Ryan K. Jones, Alaa Ali, Muralidharan Anbalagan
PDF file, 27K, Growth inhibitory effect of KX-01 in combination with paclitaxel/doxorubicin demonstrated by combinational index in ER/PR/HER2- negative breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115e74142331cd0c559f2a553f784fea
https://doi.org/10.1158/1535-7163.22498197.v1
https://doi.org/10.1158/1535-7163.22498197.v1
Autor:
Brian G. Rowan, David Hangauer, Yahao Bu, Latonya Carrier, Mei Sheng, Carolyn G. Marsden, Ryan K. Jones, Alaa Ali, Muralidharan Anbalagan
PDF file, 388K, The body weights of mice were measured either once in a week or 10 days after treatment with vehicle, KX-01, PAX and KX-01 + PAX. Tumors obtained from tumor xenograft studies were fixed, paraffin embedded and sectioned. The slides wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d521c94ab059288a6a9512a15db6468
https://doi.org/10.1158/1535-7163.22498212
https://doi.org/10.1158/1535-7163.22498212
Autor:
Brian G. Rowan, David Hangauer, Yahao Bu, Latonya Carrier, Mei Sheng, Carolyn G. Marsden, Ryan K. Jones, Alaa Ali, Muralidharan Anbalagan
PDF file, 43K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d558ff289961c1770f04299ae9bba3f
https://doi.org/10.1158/1535-7163.22498203
https://doi.org/10.1158/1535-7163.22498203
Autor:
Brian G. Rowan, David Hangauer, Bridgette M. Collins-Burow, Matthew E. Burow, Hope E. Burks, Margarite Matossian, Van Hoang, Yuanjun Gao, Yifang Zhang, Brian Fleischer, Mei Sheng, Muralidharan Anbalagan
Legends for all supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e8eb64a510dfb87f2460bb23dc4c92
https://doi.org/10.1158/1541-7786.22510765
https://doi.org/10.1158/1541-7786.22510765
Autor:
Brian G. Rowan, David Hangauer, Bridgette M. Collins-Burow, Matthew E. Burow, Hope E. Burks, Margarite Matossian, Van Hoang, Yuanjun Gao, Yifang Zhang, Brian Fleischer, Mei Sheng, Muralidharan Anbalagan
Supplementary Figure S1. KX-01 at low dose inhibited phosphorylation of Src in MDA-MB-231 xenografts. Supplementary Figure S2. Effect of KX-01 on ERα mRNA expression in Patient Derived Xenograft (PDX) tumors. Supplementary Figure S3. Effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f0114c725430090106d365c25727e7
https://doi.org/10.1158/1541-7786.22510768
https://doi.org/10.1158/1541-7786.22510768