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pro vyhledávání: '"Brian G. Bonilla"'
Autor:
Lawrence T Wang, Lais S Pereira, Patience K Kiyuka, Arne Schön, Neville K Kisalu, Rachel Vistein, Marlon Dillon, Brian G Bonilla, Alvaro Molina-Cruz, Carolina Barillas-Mury, Joshua Tan, Azza H Idris, Joseph R Francica, Robert A Seder
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010133 (2021)
Combinations of monoclonal antibodies (mAbs) against different epitopes on the same antigen synergistically neutralize many viruses. However, there are limited studies assessing whether combining human mAbs against distinct regions of the Plasmodium
Externí odkaz:
https://doaj.org/article/d385b3ce72a7496ba9242f6f5b20828b
Autor:
Mateo Reveiz, Prabhanshu Tripathi, Lais Da Silva Pereira, Patience Kiyuka, Tracy Liu, Baoshan Zhang, Yongping Yang, Brian G. Bonilla, Marlon Dillon, Myungjin Lee, Chen-Hsiang Shen, Arne Schön, Sven Kratochvil, Facundo D. Batista, Azza H. Idris, Robert A. Seder, Peter D. Kwong, Reda Rawi
SUMMARYAntibody CIS43 binds Plasmodium falciparum circumsporozoite protein (PfCSP) and protects against malaria, as recently demonstrated clinically. To improve the efficacy of CIS43, we developed an in silico pipeline to optimize the interaction ene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c85dbac3ddfcc6042ff7373d650af4
https://doi.org/10.1101/2022.04.08.487687
https://doi.org/10.1101/2022.04.08.487687