Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Brian G Jorgensen"'
Autor:
Se Eun Ha, Byungchang Jin, Brian G Jorgensen, Hannah Zogg, Lai Wei, Rajan Singh, Chanjae Park, Masaaki Kurahashi, Sei Kim, Gain Baek, Sandra M Poudrier, Moon Young Lee, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0261743 (2022)
Subepithelial platelet-derived growth factor receptor alpha (PDGFRα)+ cells found in the colonic mucosal tissue come in close contact with epithelial cells, immune cells, neurons, capillaries, and lymphatic networks. Mucosal subepithelial PDGFRα+ c
Externí odkaz:
https://doaj.org/article/ab681b055d20471e9309291e566be38b
Autor:
Moon Young Lee, Se Eun Ha, Chanjae Park, Paul J Park, Robert Fuchs, Lai Wei, Brian G Jorgensen, Doug Redelman, Sean M Ward, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176031 (2017)
Transcriptome-scale data can reveal essential clues into understanding the underlying molecular mechanisms behind specific cellular functions and biological processes. Transcriptomics is a continually growing field of research utilized in biomarker d
Externí odkaz:
https://doaj.org/article/0b530cba28cc429293fb73d1936fa8bb
Autor:
Se Eun Ha, Moon Young Lee, Masaaki Kurahashi, Lai Wei, Brian G Jorgensen, Chanjae Park, Paul J Park, Doug Redelman, Kent C Sasse, Laren S Becker, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182265 (2017)
Platelet-derived growth factor receptor alpha (PDGFRα)+ cells are distributed into distinct morphological groups within the serosal, muscular, and submucosal layers as well as the myenteric and deep muscular plexi. PDGFRα+ cells directly interact w
Externí odkaz:
https://doaj.org/article/50deaf005e3a4a19b5839b7d8a35b6d4
Autor:
Moon Young Lee, Chanjae Park, Se Eun Ha, Paul J Park, Robyn M Berent, Brian G Jorgensen, Robert D Corrigan, Nathan Grainger, Peter J Blair, Orazio J Slivano, Joseph M Miano, Sean M Ward, Terence K Smith, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171262 (2017)
Serum response factor (SRF) transcriptionally regulates expression of contractile genes in smooth muscle cells (SMC). Lack or decrease of SRF is directly linked to a phenotypic change of SMC, leading to hypomotility of smooth muscle in the gastrointe
Externí odkaz:
https://doaj.org/article/e61d17fcddeb42c798c6f15cef0042fa
Autor:
Se Eun, Ha, Brian G, Jorgensen, Lai, Wei, Byungchang, Jin, Min-Seob, Kim, Sandra M, Poudrier, Rajan, Singh, Allison, Bartlett, Hannah, Zogg, Sei, Kim, Gain, Baek, Masaaki, Kurahashi, Moon-Young, Lee, Yong-Sung, Kim, Suck-Chei, Choi, Kent C, Sasse, Samuel J S, Rubin, Andres, Gottfried-Blackmore, Laren, Becker, Aida, Habtezion, Kenton M, Sanders, Seungil, Ro
Publikováno v:
International journal of molecular sciences. 23(9)
Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in colonic mucosal PDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8595438da34ed0c056d68b0a647d5eee
https://pubmed.ncbi.nlm.nih.gov/35563399
https://pubmed.ncbi.nlm.nih.gov/35563399
Autor:
David Knupp, Brian G. Jorgensen, Hussam Z. Alshareef, Jaffar M. Bhat, Jeremy J. Grubbs, Pedro Miura, Alexander M. van der Linden
Publikováno v:
Aging Cell. 21
Accumulation of circular RNAs (circRNAs) during aging occurs on a genome-wide level for multiple organisms, but its significance is unknown. Generating circRNA loss-of-function mutants is difficult because the vast majority of these RNAs are comprise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a2526c1e3f8c78a76336a9798c11d4
https://doi.org/10.1111/acel.13560
https://doi.org/10.1111/acel.13560
Autor:
Brian G. Jorgensen, Seungil Ro
Publikováno v:
International journal of molecular sciences. 23(4)
The gastrointestinal (GI) tract in mammals is comprised of dozens of cell types with varied functions, structures, and histological locations that respond in a myriad of ways to epigenetic and genetic factors, environmental cues, diet, and microbiota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383cc033a89a765689bc39a825f23812
https://pubmed.ncbi.nlm.nih.gov/35216281
https://pubmed.ncbi.nlm.nih.gov/35216281
Publikováno v:
Journal of Personalized Medicine. 12:1762
Maturity-Onset Diabetes of the Young (MODY) is a rare form of diabetes which affects between 1% and 5% of diagnosed diabetes cases. Clinical characterizations of MODY include onset of diabetes at an early age (before the age of 30), autosomal dominan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca0073e8e0df87c5d6acfeb11bb59c3
https://doi.org/10.3390/jpm12111762
https://doi.org/10.3390/jpm12111762
Autor:
Seungil Ro, Brian G. Jorgensen
Publikováno v:
Journal of Neurogastroenterology and Motility
The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has revealed that various alterations to the DNA methylation apparatus wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9278d15f7c4820aac5fb2610b69b8a
https://doi.org/10.5056/jnm19077
https://doi.org/10.5056/jnm19077
Autor:
Sandra M. Poudrier, Seungil Ro, Hannah Zogg, Addison Morales, Kenton M. Sanders, Jong Kun Park, Andres Gottfried-Blackmore, Rajan Singh, Byungchang Jin, Lai Wei, Brian G. Jorgensen, Allison Bartlett, Se Eun Ha, Moon Young Lee, Yu Heon Chung, Sung Cho, Chanjae Park, Charles F. Ronkon, Linda Nguyen
Publikováno v:
Gastroenterology
Background & Aims Interstitial cells of Cajal (ICCs) and pancreatic β cells require receptor tyrosine kinase (KIT) to develop and function properly. Degeneration of ICCs is linked to diabetic gastroparesis. The mechanisms linking diabetes and gastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e222079c2d794f8a8942f25cdfdf7da4
https://europepmc.org/articles/PMC8532043/
https://europepmc.org/articles/PMC8532043/
