Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Brian Fulp"'
Autor:
Mary G. Sorci-Thomas, John S. Owen, Brian Fulp, Shaila Bhat, Xuewei Zhu, John S. Parks, Dharika Shah, W. Gray Jerome, Mark Gerelus, Manal Zabalawi, Michael J. Thomas
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1890-1909 (2012)
This report details the lipid composition of nascent HDL (nHDL) particles formed by the action of the ATP binding cassette transporter A1 (ABCA1) on apolipoprotein A-I (apoA-I). nHDL particles of different size (average diameters of ∼12, 10, 7.5, a
Externí odkaz:
https://doaj.org/article/4b77553386ea41c191081ca166d4443b
Publikováno v:
Biochemistry. 52:9470-9481
Apolipoprotein AI (apoA-I) is the principal acceptor of lipids from ATP-binding cassette transporter A1, a process that yields nascent high density lipoproteins. Analysis of lipidated apoA-I conformation yields a belt or twisted belt in which two str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b81ca473cd201eb95bfc4f53083835
https://doi.org/10.1021/bi401080k
https://doi.org/10.1021/bi401080k
Autor:
Brian Fulp, Mary G. Sorci-Thomas, Daniel Kreisel, Alan R. Tall, Melody A. Swartz, Marit Westerterp, Gwendalyn J. Randolph, Shu Hsia Chen, Emmanuel L. Gautier, Catherine Martel, Michael J. Thomas, Andrew M. Platt, Wenjun Li, Robert Bittman
Publikováno v:
Journal of clinical investigation, 123(4), 1571-1579. The American Society for Clinical Investigation
Reverse cholesterol transport (RCT) refers to the mobilization of cholesterol on HDL particles (HDL-C) from extravascular tissues to plasma, ultimately for fecal excretion. Little is known about how HDL-C leaves peripheral tissues to reach plasma. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d62869446240e24b706534f04d48649
https://doi.org/10.1172/jci63685
https://doi.org/10.1172/jci63685
Autor:
Michael J. Thomas, Rachel Kallinger, Mary G. Sorci-Thomas, Hao Xu, Brian Fulp, Yi Sherry Zhang, Theresa Bluemn, Ranjuna Weerasekera, Roland James, Manal Zabalawi, Kristina L. Brzoza-Lewis, Sushma Kaul, Elisa Maruko, Mark Gerelus
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d00d826aae782476bf7a20d55ae1fe1
https://pubmed.ncbi.nlm.nih.gov/27821400
https://pubmed.ncbi.nlm.nih.gov/27821400
Autor:
Mark Gerelus, Shaila Bhat, John S. Parks, Brian Fulp, John Owen, Dharika Shah, W. Gray Jerome, Manal Zabalawi, Michael J. Thomas, Xuewei Zhu, Mary G. Sorci-Thomas
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1890-1909 (2012)
This report details the lipid composition of nascent HDL (nHDL) particles formed by the action of the ATP binding cassette transporter A1 (ABCA1) on apolipoprotein A-I (apoA-I). nHDL particles of different size (average diameters of ∼ 12, 10, 7.5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc7349f555500a31c29ea7646777ca4
http://www.sciencedirect.com/science/article/pii/S0022227520418322
http://www.sciencedirect.com/science/article/pii/S0022227520418322
Autor:
Ricquita D. Pollard, Mary G. Sorci-Thomas, Xiang-An Li, Mark Gerelus, Xuewei Zhu, Nebil Nuradin, Daisy Sahoo, Michael J. Thomas, Christopher N. Blesso, Brian Fulp, Manal Zabalawi, Omar L. Francone, Erica W. Lyons
Studies in human populations have shown a significant correlation between procollagen C-endopeptidase enhancer protein 2 (PCPE2) single nucleotide polymorphisms and plasma HDL cholesterol concentrations. PCPE2, a 52-kDa glycoprotein located in the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe20ea84615f93b657f171120988ef9f
https://europepmc.org/articles/PMC4505464/
https://europepmc.org/articles/PMC4505464/
Autor:
Ricquita D. Pollard, Brian Fulp, Omar L. Francone, Manal Zabalawi, Nebil Nuradin, Erica L. Lyons, Michael J. Thomas, Mark Gerelus, Daisy Sahoo, Christopher N. Blesso, Xiang-An Li, Xuewei Zhu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Epidemiological studies have shown an inverse correlation between plasma high density lipoprotein (HDL) concentrations and cardiovascular disease risk. At variance with these observations, clinical trials that significantly raised plasma HDL-C levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0c27bb90260f8035218b31d414f5b7
https://doi.org/10.1161/atvb.35.suppl_1.320
https://doi.org/10.1161/atvb.35.suppl_1.320
Autor:
Ricquita Pollard, Christopher N Blesso, Manal Zabalawi, Brian Fulp, Erica W Lyons, Omar L Francone, Michael J Thomas, Mary G Sorci-Thomas
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Recent studies suggest that assessment of high density lipoprotein (HDL) function provides a more reliable metric of athero-protection than plasma concentration alone. One important function attributed to apolipoprotein A-I (apoA-I), the major protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56785a94ef1cfcc1eeb7d16395eb47c
https://doi.org/10.1161/atvb.34.suppl_1.671
https://doi.org/10.1161/atvb.34.suppl_1.671
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Heart disease claims nearly 400,000 individuals in the US per year. Large population studies have repeatedly demonstrated an inverse relationship between HDL concentration and risk. Despite the strong correlation, pharmacological trials that raise pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06dae469bab1abd5c0f79e984f866bf6
https://doi.org/10.1161/atvb.34.suppl_1.224
https://doi.org/10.1161/atvb.34.suppl_1.224
Autor:
Ricquita D Pollard, Erica Weiser, Christopher Blesso, Manal Zabalawi, Brian Fulp, Michael J Thomas, Mary G Sorci-Thomas
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Recent attempts to reduce cardiovascular events by pharmacologically raising plasma HDL concentration have not proven efficacious. This has lead to investigations on how to increase functional versus dysfunctional plasma HDL. Our work shows that a fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9986d62c2f5cc5910461c044c02696b0
https://doi.org/10.1161/atvb.33.suppl_1.a430
https://doi.org/10.1161/atvb.33.suppl_1.a430