Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brian Fiedler"'
Autor:
Raymond S. Norton, Brian Fiedler, Oga Buczek, Min Min Zhang, Baldomero M. Olivera, Doju Yoshikami, Grzegorz Bulaj, Layla Azam
Publikováno v:
Biochemical Pharmacology. 75:2334-2344
The excitotoxic conopeptide iota-RXIA induces repetitive action potentials in frog motor axons and seizures upon intracranial injection into mice. We recently discovered that iota-RXIA shifts the voltage-dependence of activation of voltage-gated sodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39bd37d5f1389dde9d5404b5ec1a63b
https://doi.org/10.1016/j.bcp.2008.03.019
https://doi.org/10.1016/j.bcp.2008.03.019
Autor:
Scott J. Low, Baldomero M. Olivera, Grzegorz Bulaj, Doju Yoshikami, T. Patrick Harty, Linda Chicoine, Richard T. Layer, Min Min Zhang, Brian Fiedler, Jacob S. Nielsen, Sue Wei, Heinrich Terlau, Brian D. Klein, John D. Wagstaff, Brad R. Green
Publikováno v:
Biochemistry. 45:7404-7414
μO-Conotoxin MrVIB is a blocker of voltage-gated sodium channels, including TTX-sensitive and -resistant subtypes. A comprehensive characterization of this peptide has been hampered by the lack of sufficient synthetic material. Here, we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2664503a9e290ae412e6bec1367cbab4
https://doi.org/10.1021/bi060159+
https://doi.org/10.1021/bi060159+
Autor:
Philip Catlin, Baldomero M. Olivera, Jeffrey R. McArthur, Layla Azam, Doju Yoshikami, Brian Fiedler, Heinrich Terlau, Raymond S. Norton, Grzegorz Bulaj, Brian J. Smith, Jean Rivier, Min Min Zhang, Ashley R. Chadwick, Robert J. French, Brad R. Green, Josef Gulyas
Publikováno v:
The Journal of biological chemistry. 282(42)
Peptide neurotoxins from cone snails continue to supply compounds with therapeutic potential. Although several analgesic conotoxins have already reached human clinical trials, a continuing need exists for the discovery and development of novel non-op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeb901256e30fe0b168d00e762a3d06
https://pubmed.ncbi.nlm.nih.gov/17724025
https://pubmed.ncbi.nlm.nih.gov/17724025
Autor:
Raymond S. Norton, Brian Fiedler, Grzegorz Bulaj, D. M. Wei, Jeffrey J. Babon, Olga Buczek, Xiaodong Yang, Doju Yoshikami, Baldomero M. Olivera, Ping Chen
Publikováno v:
Biochemistry. 46(35)
Conotoxin iota-RXIA, from the fish-hunting species Conus radiatus, is a member of the recently characterized I1-superfamily, which contains eight cysteine residues arranged in a -C-C-CC-CC-C-C- pattern. iota-RXIA (formerly designated r11a) is one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9956fe660defb7e59de54f8ad07928eb
https://pubmed.ncbi.nlm.nih.gov/17696362
https://pubmed.ncbi.nlm.nih.gov/17696362
Autor:
Doju Yoshikami, Grzegorz Bulaj, Brian Fiedler, Baldomero M. Olivera, Brad R. Green, Raymond S. Norton, Alex Morrison, Brian J. Smith, Philip Catlin, Min Min Zhang, Wendi Bayudan
Publikováno v:
Chemistrybiology. 14(4)
SummaryDisulfide-rich neurotoxins from venomous animals continue to provide compounds with therapeutic potential. Minimizing neurotoxins often results in removal of disulfide bridges or critical amino acids. To address this drug-design challenge, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df69e8cd2ebc1a031242029022448b9
https://pubmed.ncbi.nlm.nih.gov/17462575
https://pubmed.ncbi.nlm.nih.gov/17462575
Autor:
Grzegorz, Bulaj, Min-Min, Zhang, Brad R, Green, Brian, Fiedler, Richard T, Layer, Sue, Wei, Jacob S, Nielsen, Scott J, Low, Brian D, Klein, John D, Wagstaff, Linda, Chicoine, T Patrick, Harty, Heinrich, Terlau, Doju, Yoshikami, Baldomero M, Olivera
Publikováno v:
Biochemistry. 45(23)
MuO-conotoxin MrVIB is a blocker of voltage-gated sodium channels, including TTX-sensitive and -resistant subtypes. A comprehensive characterization of this peptide has been hampered by the lack of sufficient synthetic material. Here, we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d10d3d549fc48fdc1b4161ec648cd6c
https://pubmed.ncbi.nlm.nih.gov/16752929
https://pubmed.ncbi.nlm.nih.gov/16752929
Autor:
Brad R. Green, Phillip Catlin, Baldomero M. Olivera, Brian J. Smith, Min Min Zhang, Brian Fiedler, James E. Garrett, Doju Yoshikami, Maren Watkins, Grzegorz Bulaj
Publikováno v:
Biochemistry. 45(11)
mu-Conotoxins are peptides that block sodium channels. Molecular cloning was used to identify four novel mu-conotoxins: CnIIIA, CnIIIB, CIIIA, and MIIIA from Conus consors, C. catus and C. magus. A comparison of their sequences with those of previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d0c86f0b467a3945f6a32c64008440
https://pubmed.ncbi.nlm.nih.gov/16533055
https://pubmed.ncbi.nlm.nih.gov/16533055
Autor:
Brian Fiedler
Publikováno v:
Numerical Methods in Fluid Mechanics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89cbec239d9e02fa3b02d726c7f13f5
https://doi.org/10.1090/crmp/016/05
https://doi.org/10.1090/crmp/016/05
