Výsledky vyhledávání - "Brian F.C. Clark"

Autor: Frank Massino, Jan Barciszewski, Brian F.C. Clark

Publikováno v: International Journal of Biological Macromolecules. 40:182-192

Cytokinins are important adenine derivatives that serve as hormones to control many processes in plants. They were discovered as factors that promote cell division in tobacco tissue cultures and have been shown also to regulate several other developm

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https://doi.org/10.1016/j.ijbiomac.2006.06.024

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Deconstructing PTI-1: PT1-1 is a truncated, but not mutated, form of translation elongation factor 1A1, eEF1A1

Autor: Brian F.C. Clark, Charlotte R. Knudsen, Francisco Mansilla, Niels Ole Kjeldgaard, Helle Jakobsen, Lise Lotte Hansen

Publikováno v: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1727:116-124

The prostate tumor-inducing gene 1 (PTI-1) transcript is detected in various human carcinoma cells. PTI-1 is reported to consist of a 5′ untranslated region (5′ UTR) homologous to mycoplasma 23S rRNA and a coding region corresponding to a truncat

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https://doi.org/10.1016/j.bbaexp.2004.12.012

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Informed consent of very old patients and modern genomics

Autor: Erica Haimes, Brian F.C. Clark, Anne-Marie Duguet, Olivier Toussaint, Christian Swine, Eric Matthews

Publikováno v: Biogerontology. 6:81-84

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https://doi.org/10.1007/s10522-004-7388-5

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Qβ-Phage Resistance by Deletion of the Coiled-coil Motif in Elongation Factor Ts

Autor: Brian F.C. Clark, Sander G.J. Mathu, Charlotte R. Knudsen, Barend Kraal, Henrik Karring, Jan van Duin

Publikováno v: Journal of Biological Chemistry. 279:1878-1884

Elongation factor Ts (EF-Ts) is the guanine-nucleotide exchange factor of elongation factor Tu (EF-Tu), which promotes the binding of aminoacyl-tRNA to the mRNA-programmed ribosome in prokaryotes. The EF-Tu.EF-Ts complex, one of the EF-Tu complexes d

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https://doi.org/10.1074/jbc.m306605200

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Functional effects of deleting the coiled-coil motif inEscherichia colielongation factor Ts

Autor: Charlotte R. Knudsen, Henrik Karring, Asgeir Björnsson, Søren Thirup, Brian F.C. Clark

Publikováno v: European Journal of Biochemistry. 270:4294-4305

Elongation factor Ts (EF-Ts) is the guanine nucleotide-exchange factor for elongation factor Tu (EF-Tu) that is responsible for promoting the binding of aminoacyl-tRNA to the mRNA-programmed ribosome. The structure of the Escherichia coli EF-Tu-EF-Ts

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https://doi.org/10.1046/j.1432-1033.2003.03822.x

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'Action-at-a distance' of a new DNA oxidative damage product 6-furfuryl-adenine (kinetin) on template properties of modified DNA

Autor: Wojciech T. Markiewicz, Maria Markiewicz, Maciej Szymanski, Jan Barciszewski, Eliza Wyszko, Miroslawa Z. Barciszewska, Brian F.C. Clark

Publikováno v: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1625:239-245

N(6)-furfuryladenine (kinetin, K) was shown to have cytokinin activity and antiageing effects. It also appears to protect DNA against oxidative damage mediated by the Fenton reaction. Kinetin was identified as a natural component of DNA in plant extr

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https://doi.org/10.1016/s0167-4781(02)00622-x

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Mapping the human translation elongation factor eEF1H complex using the yeast two-hybrid system

Autor: Francisco Mansilla, Brian F.C. Clark, Mandana Jadidi, Irene Friis, Charlotte R. Knudsen, Karen Margrethe Nielsen

Publikováno v: Mansilla, F, Friis, I, Jadidi, M, Nielsen, K M, Clark, B F C & Knudsen, C R 2002, ' Mapping the human translation elongation factor eEF1H complex using the yeast two-hybrid system. ', Biochemical Journal, vol. 365, no. Pt 3, pp. 669-76 . https://doi.org/10.1042/BJ20011681

Udgivelsesdato: Aug 1 In eukaryotes, the eukaryotic translation elongation factor eEF1A responsible for transporting amino-acylated tRNA to the ribosome forms a higher-order complex, eEF1H, with its guanine-nucleotide-exchange factor eEF1B. In metazo

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https://doi.org/10.1042/bj20011681

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[Untitled]

Autor: Suresh I. S. Rattan, Brian F.C. Clark, Marianne Deries, Philippe Verbeke

Publikováno v: Biogerontology. 3:117-120

Repeated mild heat shock (RMHS) has anti-aging effects on growth and various other cellular and biochemical characteristics of human skin fibroblasts undergoing aging in vitro. In this study, we have tested whether RMHS can reduce the accumulation of

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https://doi.org/10.1023/a:1015284119308

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Recognition of Aminoacyl-tRNAs by Protein Elongation Factors

Autor: Mathias Sprinzl, Jan Barciszewski, Brian F.C. Clark, Morten Kjeldgaard

The interactive recognition of nucleic acids by proteins is a central process in the regulation of gene expression. To gain insight into such interactions requires a knowledge of appropriate three-dimensional structures and information on biochemical

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https://doi.org/10.1128/9781555818333.ch21

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The crystallization and structural determination of tRNA

Autor: Brian F.C. Clark

Publikováno v: Trends in Biochemical Sciences. 26:511-514

I thank Ray Brown, Aaron Klug, Kjeld Marcker, Daniela Rhodes and Jan Barciszewski for critical reading of the manuscript and helpful suggestions.

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https://doi.org/10.1016/s0968-0004(01)01910-7

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