Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Brian F. Kaller"'
Publikováno v:
The Journal of Organic Chemistry. 61:5498-5505
Two closely related syntheses of 5,6-O-(2-propylidene)-N-desalanyl-N-2-(trimethylsilyl)ethanesulfonyl]bactobolin (9b) from (+)-12, an intermediate previously prepared from d-glucose, are reported. In each case, the key step involves a precedented ste
Publikováno v:
The Journal of Organic Chemistry. 60:7830-7836
Autor:
Dale E. Ward, Brian F. Kaller
Publikováno v:
The Journal of Organic Chemistry. 59:4230-4238
The synthesis of 5,6-O-(2-propylidene)-N-desalanyl-N-[(4-methylphenyl)methanesulfonyl]actinobolin (37) is reported. The carbocyclic ring of 37 is constructed by a novel [3+3] annulation method involving sequential two-electron and one-electron allyla
Publikováno v:
Tetrahedron Letters. 35:3485-3488
The preparation of (-)- 16 from (+)- 3 constitutes a formal enantiospecific synthesis of (-)-bactobolin from D-glucose. The key transformation involves the diastereoselective addition of LiCHCl 2 to 7 in the presence of CeCl 3 . The synthesis of (+)-
Publikováno v:
Tetrahedron Letters. 34:8047-8050
An efficient, stereoselective synthesis of an enantiomerically pure C-ring precursor 14-S of O-cinnamoyltaxicins-I and -II has been achieved from 3-methyl-2-cyclohexen-1-ol, using a [2,3] Wittig rearrangement as the key step.
Autor:
Dale E. Ward, Brian F. Kaller
Publikováno v:
Tetrahedron Letters. 34:407-410
The carbocyclic ring of actinobolin was constructed by a [3+3] annulation of a D-galactosamine derivative with 3-phenylthio-2- (trimethylsilylmethyl)propene. Formation of the lactone and acylation with L- alanine according to literature precedent gav
Autor:
Dale E. Ward, Brian F. Kaller
Publikováno v:
ChemInform. 22
3-phenylthio-2-(trimethylsilymethyl)propene is a convenient conjunctive reagent for the preparation of methylenecyclohexanes via a [3+3] annulation. The trimethylsilyl group facilitates the Lewis acid catalyzed allylation of an aldehyde or acetal whi
Publikováno v:
ChemInform. 25
An efficient, stereoselective synthesis of an enantiomerically pure C-ring precursor 14-S of O-cinnamoyltaxicins-I and -II has been achieved from 3-methyl-2-cyclohexen-1-ol, using a [2,3] Wittig rearrangement as the key step.
Publikováno v:
ChemInform. 25
The preparation of (-)- 16 from (+)- 3 constitutes a formal enantiospecific synthesis of (-)-bactobolin from D-glucose. The key transformation involves the diastereoselective addition of LiCHCl 2 to 7 in the presence of CeCl 3 . The synthesis of (+)-
Publikováno v:
ChemInform. 27