Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brian F. Hinnebusch"'
Autor:
Moushumi Mozumder, Richard A. Hodin, J. Welles Henderson, Lee M. Ocuin, Aleem Siddique, Vincent W. Yang, Madhu S. Malo, Mario A. Abedrapo, Wenying Zhang, Brian F. Hinnebusch
Publikováno v:
Journal of Gastrointestinal Surgery. 7:1053-1061
The gut-enriched Krüppel-like factor (KLF4) and the ligand-bound thyroid hormone receptor (TR) have each been shown to play a critical role in mammalian gut development and differentiation. We investigated an interrelationship between these two pres
Autor:
Richard A. Hodin, Qing Ma, Sonia Y. Archer, Aleem Siddique, J. Welles Henderson, Brian F. Hinnebusch
Publikováno v:
Journal of Gastrointestinal Surgery. 6:403-409
Enterocytes at the tips of microvilli are more sensitive to an ischemic insult than those cells residing in the crypts, an effect thought to be due to a relative lack of collateral flow. We speculated that this increased cellular sensitivity to ische
Publikováno v:
The Journal of Nutrition. 132:1012-1017
The short-chain fatty acid (SCFA) butyrate is produced via anaerobic bacterial fermentation within the colon and is thought to be protective in regard to colon carcinogenesis. Although butyrate (C4) is considered the most potent of the SCFA, a variet
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 280:G482-G490
The role of histone hyperacetylation in regard to growth, differentiation, and apoptosis in colon cancer cells was assessed in an in vitro model system. HT-29 cells were grown in ±10% fetal bovine serum with either 5 mM sodium butyrate or 0.3 μM tr
Autor:
Mario A. Abedrapo, Aleem Siddique, Vincent W. Yang, Madhu S. Malo, J. Welles Henderson, Xin-Ming Chen, Wenying Zhang, Richard A. Hodin, Christopher P. Athaide, Brian F. Hinnebusch
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 286(1)
We have examined the role that the transcription factor gut-enriched Krüppel-like factor (KLF4 or GKLF) plays in activating the enterocyte differentiation marker gene intestinal alkaline phosphatase (IAP). A yeast one-hybrid screen was used to ident
Autor:
Wenying Zhang, J. Welles Henderson, Mario A. Abedrapo, Brian F. Hinnebusch, Madhu S. Malo, Aleem Siddique, Richard A. Hodin
Publikováno v:
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 7(2)
Enterocyte differentiation is thought to occur through the transcriptional regulation of a small subset of specific genes. A recent growing body of evidence indicates that post-translational modifications of chromatin proteins (histones) play an impo
Publikováno v:
Gastroenterology. 120:A62-A62
Publikováno v:
Journal of the American College of Surgeons. 191:S56