Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Brian E. Eisinger"'
Autor:
Yu Gao, Minjie Shen, Jose Carlos Gonzalez, Qiping Dong, Sudharsan Kannan, Johnson T. Hoang, Brian E. Eisinger, Jyotsna Pandey, Sahar Javadi, Qiang Chang, Daifeng Wang, Linda Overstreet-Wadiche, Xinyu Zhao
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108114- (2020)
Externí odkaz:
https://doaj.org/article/15d8a0b3f45f46098c3e387d60482069
Autor:
Yue Li, Michael E. Stockton, Brian E. Eisinger, Yinghua Zhao, Jessica L. Miller, Ismat Bhuiyan, Yu Gao, Zhiping Wu, Junmin Peng, Xinyu Zhao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Loss of fragile X mental retardation protein (FMRP) leads to fragile X syndrome, associated with cognitive dysfunction. Here the authors show that mice lacking FMRP show reduced hippocampal neurogenesis and cognitive deficits, which can be rescued by
Externí odkaz:
https://doaj.org/article/26fc57d7c2ad436ca758e946a648f712
Publikováno v:
Proceedings of IMPRS. 5
Objective/Hypothesis: The apoliprotein E epsilon 4 (APOE4) variant is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD) and is associated with accelerated clinical disease. Increasing evidence suggests that the immune system
Autor:
Qiping Dong, Jose Carlos Gonzalez, Minjie Shen, Yu Gao, Jyotsna Pandey, Xinyu Zhao, Brian E. Eisinger, Daifeng Wang, Sudharsan Kannan, Johnson T. Hoang, Qiang Chang, Sahar Javadi, Linda Overstreet-Wadiche
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108114-(2020)
Cell Reports, Vol 32, Iss 5, Pp 107997-(2020)
Cell Rep
Cell reports
Cell Reports, Vol 32, Iss 5, Pp 107997-(2020)
Cell Rep
Cell reports
Summary: Voluntary running enhances adult hippocampal neurogenesis, with consequences for hippocampal-dependent learning ability and mood regulation. However, the underlying mechanism remains unclear. Here, we show that voluntary running induces uniq
Autor:
Junmin Peng, Jessica L. Miller, Zhiping Wu, Yu Gao, Brian E. Eisinger, Yinghua Zhao, Xinyu Zhao, Yue Li, Ismat Bhuiyan, Michael E. Stockton
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
Fragile X syndrome (FXS) is the most prevalent inherited intellectual disability, resulting from a loss of fragile X mental retardation protein (FMRP). Patients with FXS suffer lifelong cognitive disabilities, but the function of FMRP in the adult br
Autor:
Xinyu Zhao, Brian E. Eisinger
Publikováno v:
Cell and Tissue Research. 371:7-21
Adult hippocampal neurogenesis occurs throughout life and supports healthy brain functions. The production of new neurons decreases with age and deficiencies in adult neurogenesis are associated with neurodevelopmental and degenerative disease. The r
Publikováno v:
Frontiers in Neuroendocrinology. 42:1-17
Changes in expression of hundreds of genes occur during the production and function of the maternal brain that support a wide range of processes. In this review, we synthesize findings from four microarray studies of different maternal brain regions
Publikováno v:
Cerebral Cortex. 27:2064-2077
In mammalian hippocampus, new neurons are continuously produced from neural stem cells throughout life. This postnatal neurogenesis may contribute to information processing critical for cognition, adaptation, learning, and memory, and is implicated i
Publikováno v:
Neuroscience. 312:130-140
MicroRNAs (miRNAs) inhibit RNA targets and may contribute to postpartum central nervous system (CNS) gene expression changes, although this has never been tested. In the present study, we directly evaluated miRNA levels using RNA sequencing during re
Autor:
Jenny T. Chen, Samuel O. Poore, John W. Siebert, Corinne R. Esquibel, Kevin W. Eliceiri, Brian E. Eisinger
Publikováno v:
Plastic and reconstructive surgery. 142(3)
BACKGROUND Parry-Romberg syndrome is an enigmatic craniofacial disorder characterized by progressive facial atrophy. The pathogenesis and molecular mechanisms governing Parry-Romberg syndrome have never before been described. The purpose of the curre